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Melanogenesis-promoting effect of Cirsium japonicum flower extract in vitro and ex vivo / Minkyung Kim in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 6 (12/2021)
[article]
Titre : Melanogenesis-promoting effect of Cirsium japonicum flower extract in vitro and ex vivo Type de document : document électronique Auteurs : Minkyung Kim, Auteur ; Kyungeun Jeon, Auteur ; Seoungwoo Shin, Auteur ; Sohyun Yoon, Auteur ; Hayeon Kim, Auteur ; Hee Young Kang, Auteur ; Dehun Ryu, Auteur ; Deokhoon Park, Auteur ; Eunsun Jung, Auteur Année de publication : 2021 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Adénosine monophosphate cyclique L'adénosine monophosphate cyclique (ou AMP cyclique ou AMPc) est une molécule biologique qui agit souvent en tant qu'intermédiaire, dans l'action des hormones ou des neurotransmetteurs notamment. Elle fait partie des seconds messagers.
Cosmétiques
Extraits de plantes:Extraits (pharmacie)
Follicule pileux
Mélanogénèse
Peau -- Soins et hygiène
Peau reconstituée
Pigmentation de la peau
Pigmentation, Troubles de laIndex. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : In this study, we examined the effect of C. japonicum flower extract (CFE) on melanogenesis and its mechanism in vitro and ex vivo.
- Methods : The effect of CFE on melanogenesis was investigated with lightly (HEMn-LP) and moderately (HEMn-MP) pigmented normal human melanocytes, reconstituted three-dimensional skin (3D skin) model and ex vivo human hair follicles. The melanogenesis-inducing effect of CFE was evaluated using melanin content and intracellular tyrosinase activity assay. The amount and type of eumelanin and pheomelanin were analysed by using HPLC method. The mechanism involved in the effect of CFE on hyperpigmentation was explored by cyclic adenosine monophosphate (cAMP) immunoassay and western blot analysis for tyrosinase, microphthalmia-associated transcription factor (MITF) and phosphorylated CRE-binding protein (pCREB) expression. The degree of pigmentation in 3D skin and L-values were measured using a CR-300 chroma meter. The amount of dissolved melanin was measured using a spectrophotometer. The content of melanin in the hair follicles was evaluated by Fontana Masson staining.
- Results : C. japonicum flower extract significantly increased the melanin content and cellular tyrosinase activity in both HEMn-LP and HEMn-MP cells. The markers of pheomelanin and eumelanin in HEMn-LP and HEMn-MP were also increased by CFE. We observed that CFE treatment on melanocytes increased intracellular cAMP with inducing pCREB and up-regulating the protein levels of TYR and MITF. Furthermore, CFE considerably increased the melanin content in a 3D skin model and ex vivo human hair follicles.
- Conclusions : These results suggest that CFE exerts hyperpigmentation activity through cAMP signalling in human melanocytes that it can improve follicular depigmentation and vitiligo by stimulating the melanin synthesis.Note de contenu : - MATERIALS AND METHODS : Materials - Cell culture and viability assay - Melanin content and cell viability assay - Analysis of eumelanin and pheomelanin by HPLC - Cellular tyrosinase activity - Cyclic AMP immunoassay - Western blot analysis - The reconstituted three-dimensional human skin model - Ex vivo human hair follicles - Statistical analysis
- RESULTS : Effect of CFE on the melanin content of lightly and moderately pigmented human melanocytes - Analysis on markers of pheomelanin and eumelanin - Effect of CFE on cellular tyrosinase activity - Effect of CFE on cAMP signalling pathway - Melanogenic effect of CFE on 3D skin model
- Table 1 : TTCA and PTCA as specific markers in lightly and moderately pigmented melanocytesDOI : https://doi.org/10.1111/ics.12746 En ligne : https://drive.google.com/file/d/1ujuVw-VGc03qkR-B5zlcoeYHm0Vn4ygI/view?usp=shari [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37051
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 6 (12/2021)[article]N° 107 - 2015 - Formulation (Bulletin de COSMETO VEILLE) / Julien Romestant
[n° ou bulletin]
est un bulletin de COSMETO VEILLE / Julien Romestant / Chartres [France] : Cosmetic Valley Editions (2014)
Titre : N° 107 - 2015 - Formulation Type de document : texte imprimé Auteurs : Julien Romestant, Auteur Année de publication : 2015 Importance : 48 p. Présentation : ill. Format : 29 cm Langues : Multilingue (mul) Catégories : Agents de blanchiment
Antiâge
Barrière cutanée
Biomolécules actives
Cicatrisation
Commerce
Conservateurs (chimie)
Cosmétiques
Diffusion (physique)
Emulsions -- Emploi en cosmétologie
Formulation (Génie chimique)
Imagerie (technique)
Microbiologie
Peau -- Effet du rayonnement ultraviolet
Peau -- Soins et hygiène
Photovieillissement (dermatologie)
Pigmentation de la peau
Produits antisolaires
Surfactants
Texturants
Vecteurs (pharmacie)
Veille technologiqueIndex. décimale : 668.5 Parfums et cosmétiques Note de contenu : - BUSINESS : Investissement - Fusion-acquisition
- SENSORIEL - BIEN ÊTRE
- FORMULATION : Agents de texture - Agent de surface - Emulsion - Microbiologie - Conservateurs - Agents de diffusion/vecteurs
- CONNAISSANCE DE LA PEAU : Imagerie de la peau - Cicatrisation - Fonction barrière - Innocuité
- ANTI-ÂGE : Actifs anti-âge - Photo-vieillissement - Solaire
- PIGMENTATION-ECLAT : Eclat de la peau - BlanchimentPermalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=bulletin_display&id=16381 [n° ou bulletin]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 17620 - Périodique Bibliothèque principale Documentaires Disponible Natural extremolyte fights pigmentation caused by environmental stressors / Janina Kienemund in SOFW JOURNAL, Vol. 145, N° 7/8 (07-08/2019)
[article]
Titre : Natural extremolyte fights pigmentation caused by environmental stressors Type de document : texte imprimé Auteurs : Janina Kienemund, Auteur Année de publication : 2019 Article en page(s) : p. 32-35 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Agents de blanchiment
Antioxydants
Biomolécules actives
Cosmétiques
Lumière bleue
Peau -- Effets de la pollution atmosphérique
Peau -- Soins et hygiène
Pigmentation de la peau
Protection cutanéeIndex. décimale : 668.5 Parfums et cosmétiques Résumé : The natural extremolyte bitop Ectoin® natural shows comprehensive skin protection efficacy against multiple external stress factors initiating pigmentation, in this case particulate matter and blue light irradiation. It effectively reduces pollution induced POMC gene expression and is capable to protect skin and skin cells from the whole spectrum of air pollution including PAHs, heavy metals as well as PM of all particle sizes. bitop Ectoin® natural also prevents blue light induced pigmentation and oxidative stress and additionally supports gentle skin lightening during long-term application. Furthermore, the natural active ingredient is supported by more than 15 years of published clinical data, proving its safety and efficacy for various applications including its therapeutic use in medical products. Note de contenu : - Protection against pollution induced pigmentation
- Protection against blue light induced pigmentation
- Whitening and lightening efficacy
- Fig. 1 : Up-regulation of POMC mRNA expression in primary human keratinocytes (Asian and Caucasian) by ultrafine (Printex90) and fine (Huber990) carbon black particles and by two different types of exhaust particulates (SRM1650, SRM2975)
- Fig. 2 : MC1R immunostaining of the negative control, placebo and 1% bitop Ectoin® natural pre-treatment batch with and without visible light irradiation
- Table 1 : Depigmenting effect and skin lightening
- Table 2 : Reduction of different pigmentationsEn ligne : https://drive.google.com/file/d/1pcDCxfhlrjkg8EkGcCTUC5oGK8XEopTh/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=32960
in SOFW JOURNAL > Vol. 145, N° 7/8 (07-08/2019) . - p. 32-35[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 21165 - Périodique Bibliothèque principale Documentaires Disponible New melanobreaker strategy for skin whitening / Eve Bosseboeuf in PERSONAL CARE EUROPE, Vol. 14, N° 3 (06/2020)
[article]
Titre : New melanobreaker strategy for skin whitening Type de document : texte imprimé Auteurs : Eve Bosseboeuf, Auteur ; Gabrielle Moro, Auteur ; Pierre-Yves Morvan, Auteur Année de publication : 2020 Article en page(s) : p. 43-46 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Agents de blanchiment
Chromophycophytes
Dermo-cosmétologie
Extraits de plantes:Extraits (pharmacie)
Ingrédients cosmétiques
Peau -- Soins et hygiène
Pigmentation de la peau
Taches pigmentaires (dermatologie)Index. décimale : 668.5 Parfums et cosmétiques Résumé : Science and new technology have made molecular data accessible and it is thanks to this informational context that we are able to identify the main players involved in the skin pigmentation process.
Genes that use signalling pathways are this study's ideal targets for assessing the efficacy of the main active agents to be developed. In the laboratory, a new brown algae extract has been revealed to us with potential implications for regulating the expression of genes participating in melanogenesis. The results have indeed come to show that the extract is able to inhibit the expression of those genes responsible for melanin synthesis activation, as well as to activate the genes responsible for their degradation. In addition to possessing uncommon properties by virtue of the alga’s iridescence, this extract, called CyWhite, helps to naturally rebalance skin pigmentation.Note de contenu : - Melanogenesis : how does skin get its colour ?
- Genes involved in skin pigmentation regulation : ideal targets
- In vivo efficacy : overall assessment of homogeneity and lightening effect
- Fig. 1 : The rainbow algae in its natural environment and its hand harvesting
- Fig. 2 : Regulatory genes involved in pigment synthesis pathways in the keratinocytes and melanocytes
- Fig. 3 : Expression of POMC and CSTE in reconstituted epidermis models treated or not with CyWhite
- Fig. 4 : Expression of AGRP, DKKA and CTSL2 in reconstituted epidermis model treated or not with CyWhite
- Fig. 5 : Effect of CyWhite on ITA° of pigmentation spots of the face after 8 weeks of application compared to the placebo
- Fig. 6 : Effect of CyWhite on the colour difference ΔE between a pigmentation spot and the "normal" skin of the face
- Fig. 7 : Extract from responses by volunteers to the self-assessment questionnaireEn ligne : https://drive.google.com/file/d/1X9VZNUNaCJanOJPJelsJq4zB54oRWEri/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34278
in PERSONAL CARE EUROPE > Vol. 14, N° 3 (06/2020) . - p. 43-46[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 21749 - Périodique Bibliothèque principale Documentaires Disponible Novel pentapeptide enhances skin's natural, healthy glow by boosting MC1R / Dominik Imfeld in SOFW JOURNAL, Vol. 146, N° 10 (10/2020)
[article]
Titre : Novel pentapeptide enhances skin's natural, healthy glow by boosting MC1R Type de document : texte imprimé Auteurs : Dominik Imfeld, Auteur ; Francesca Pascucci, Auteur Année de publication : 2020 Article en page(s) : p. 50-55 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Biomolécules actives
Cosmétiques
Peau -- Soins et hygiène
Peptides
Pigmentation de la peauIndex. décimale : 668.5 Parfums et cosmétiques Résumé : To address an identified consumer demand for skin care products that can create a natural-looking, lightly suntanned complexion all year round, DSM has been investigating safe means of stimulating skin pigmentation. Its novel pentapeptide Benzoyl Dipeptide-18 D-Phenylalanyl Arginyl D-Tryptophan Diproylamide Mesylate (trading under the name SYN-GLOWâ„¢) has been designed and synthesized to act as a melanocortin 1 receptor (MC1R) agonist. Its efficacy has been tested in ex-vivo and in-vivo studies which have demonstrated its potential to initiate and enhance skin pigmentation, with long-lasting results. The findings are presented here. Note de contenu : - A lightly tanned complexion is desirable to many consumers
- Could activating MC1R with a synthetic peptide offer a safe, sustainable answer ?
- Ex-vivo investigation and findings
- Study findings confirm enhanced and long-lasting pigmentation in-vivo
- Consumer perceptions from facial application of pentapeptideEn ligne : https://drive.google.com/file/d/1EzntfHqHMXOx3hhD8Xu0ivOLavs7XPaQ/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34600
in SOFW JOURNAL > Vol. 146, N° 10 (10/2020) . - p. 50-55[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 22345 - Périodique Bibliothèque principale Documentaires Disponible Oxidative stress in the skin : Impact and related protection / Juanjuan Chen in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 5 (10/2021)
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