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Brain Activation in Response to a Tactile stimulation : functional magnetic resonance imaging (fMRI) versus cognitive analysis / Bernard Querleux in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 21, N° 2 (04/1999)
[article]
Titre : Brain Activation in Response to a Tactile stimulation : functional magnetic resonance imaging (fMRI) versus cognitive analysis Type de document : texte imprimé Auteurs : Bernard Querleux, Auteur ; G. Gazano, Auteur ; O. Mohen-Domenech, Auteur ; J. Jacquin, Auteur ; Y. Burnod, Auteur ; P. Gaudion, Auteur ; O. Jolivet, Auteur ; J. Bittoun, Auteur ; H. Benali, Auteur Année de publication : 1999 Article en page(s) : p. 107-118 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Imagerie cérébrale' 'IRM fonctionnelle' 'Cortex somatosensoriel' 'Stimulation tactile' 'Peau humaine' Index. décimale : 668.5 Parfums et cosmétiques Résumé : The aim of this study was to compare fMRI analysis of somatosensory areas activated by passive touch, to cognitive analysis of the psychological profile of human subjects. Methods. The study was carried out on 21 females, after informed consent. Two artificial textures (smooth and rough), and two natural textures (the skin of an operator modified or not by a cosmetic product), were applied on the fingers of the subjects. A period of imagination to be touched was also included in the study. MR images of the somatosensory cortex were acquired on a 1.5T MRI system during the different behavioral conditions. Series of images were first processed to compensate for the inter-frame motions and then activation was assessed with a statistical method based on conditional analysis. After the MRI protocol, each subject was interviewed following a questionnaire from which psychological descriptors were extracted. Results. 1) Activations were quite similar for all textures in the contralateral sensory areas 2) In the ipsilateral sensory areas, activations were more important in response to a stimulation with the skin of an operator than with artificial textures. The activation was even more important after application of a cosmetic product on the skin. 3) Imagination of the tactile stimulation resulted in an activation mostly localized in the ipsilateral cortex. 4) A PLS analysis assessed that 2 psychological descriptors, rationality and sensorial reactivity, were related to an activation in the contralateral cortex, while 2 others, imagination and sensitivity, were related to ipsilateral areas activation. Conclusion. fMRI and cognitive analysis allowed us to map the physical component of the tactile perception in the contralateral cortex. This study also gave rise to a better understanding of the activation in ipsilateral areas, which was found to be mainly related to the subjective component of the stimulation. DOI : 10.1046/j.1467-2494.1999.198270.x En ligne : https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.198270.x Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26496
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 2 (04/1999) . - p. 107-118[article]Comparative topical absorption and antioxidant effectiveness of two forms of coenzyme Q10 after a single dose and after long-term supplementation in the skin of young and middle-aged subjects / Joe Vinson in IFSCC MAGAZINE, Vol. 8, N° 4 (10-11-12/2005)
[article]
Titre : Comparative topical absorption and antioxidant effectiveness of two forms of coenzyme Q10 after a single dose and after long-term supplementation in the skin of young and middle-aged subjects Type de document : texte imprimé Auteurs : Joe Vinson, Auteur ; Sunil Anamandla, Auteur Année de publication : 2005 Article en page(s) : p. 287-292 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Coenzyme Q10' 'Peau humaine' 'Péroxydes lipidiques' Antioxydants 'Stratum corneum' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Coenzyme Q10 is an endogenous antioxidant found in the skin along with vitamins A, C and E. Coenzyme Q10 is used
increasingly in cosmetic products and is advertised as a skin energizer, protector against skin aging, skin repairer, and
an anti-wrinkling agent. As the outermost layer of skin, the stratum corneum is the interface between the body and
the environment and requires antioxidants to protect it and the epidermis and dermis below it. Nutrient levels in the
stratum corneum correlate with those in the skin. Two forms of coenzyme Q10 (pure coenzyme Q10 and a yeast-based
coenzyme Q10) were investigated in a commercial vehicle. Two groups of subjects were tested aged 21-29 and 51-70,
respectively. Coenzyme Q10 absorption in the stratum corneum was determined after a 1-hour application and ethanol
extraction. Significantly more yeast coenzyme Q10 was absorbed than the pure coenzyme Q10 and the middle-aged
subjects absorbed about twice as much coenzyme Q10 as did the younger subjects. Skin antioxidants were significantly
increased by yeast coenzyme Q10 but not by pure coenzyme Q10. Peroxides declined in the stratum corneum
after twice daily application of coenzyme Q10 with both forms but the decrease was greater with the yeast form. The
older subjects had significantly higher baseline levels of lipid peroxides than did the younger group, indicating an increase
in skin oxidative damage with age. The yeast coenzyme Q10 is the superior form of coenzyme Q10 for human
skin application.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10451
in IFSCC MAGAZINE > Vol. 8, N° 4 (10-11-12/2005) . - p. 287-292[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003889 - Périodique Bibliothèque principale Documentaires Disponible A comparison of the in vitro permeation of 3-O-ethyl-l-ascorbic acid in human skin and in a living skin equivalent (LabSkin™) / Fotis Iliopoulos in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 1 (02/2021)
[article]
Titre : A comparison of the in vitro permeation of 3-O-ethyl-l-ascorbic acid in human skin and in a living skin equivalent (LabSkin™) Type de document : document électronique Auteurs : Fotis Iliopoulos, Auteur ; Alex Chapman, Auteur ; Majella E. Lane, Auteur Année de publication : 2021 Article en page(s) : p. 107-112 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Barrière cutanée
Vitamine CTags : 'Acide 3-O-éthyl-l-ascorbique' 'Equivalent peau humaine' LabSkin ™ 'Barrière cutanée' 'Livraison de la peau' Perméation 'Absorption Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objectives : The safety assessment of personal care products often entails determining dermal absorption of their ingredients. Such experiments are typically performed in human or animal skin in vitro; however, ethical and safety considerations are associated with obtaining these tissues. Several human skin equivalent models (HSEs) have been developed as alternatives to human tissue. The barrier function of such models however, is normally less developed than human skin. Here, we examine the permeability of the HSE LabSkinTM to a model compound, 3-O-ethyl-l-ascorbic acid (EA) compared with human skin.
- Methods : Skin uptake and permeation of EA was investigated in vitro using heat-separated human epidermis and LabSkinTM. Finite dose (5 μL cm-2) Franz-diffusion studies were conducted using 2 % (w/w) EA in a ternary solvent mixture comprising propylene glycol (PG), propylene glycol monolaurate (PGML), and isopropyl myristate (IPM). These excipients are commonly used in cosmetic products and they have been reported to promote permeation of EA in a different model, namely porcine skin.
- Results : Permeation of EA through LabSkinTM was evident from 2 h ; however, EA permeation in human skin was not detected until 5 h. Similar amounts of EA permeated through the two membranes at time points 8, 10, 12 and 24 h (p > 0.05). The cumulative amounts of EA delivered through LabSkinTM at 24 h were 41.3 ± 2.0 µg cm−2, corresponding to 55.1 ± 1.8 % of the applied dose. Similar amounts permeated across human skin, 49.4 ± 4.1 µg cm−2, accounting for 58.0 ± 4.2 % of the dose applied (p > 0.05).
- Conclusion : The permeation of EA in LabSkinTM compared well with results for human epidermis in terms of the permeation profiles and the cumulative amounts of EA that permeated. The data suggest that the skin barrier of the two models was similar with regard to their overall permeability to the hydrophilic active EA. The findings are promising for the use of LabSkinTM as a surrogate for human skin in permeability testing. Future studies will focus on exploring the reproducibility and robustness of LabSkinTM for delivery of other actives that span a range of physicochemical properties.DOI : https://doi.org/10.1111/ics.12675 En ligne : https://drive.google.com/file/d/18D4sVi7kxi_s1HySIKy3cou71CIz_-RM/view?usp=shari [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35449
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 1 (02/2021) . - p. 107-112[article]Multicenter study on measurement of the natural pH of the skin surface / Doerte Segger in IFSCC MAGAZINE, Vol. 10, N° 2 (04-05/2007)
[article]
Titre : Multicenter study on measurement of the natural pH of the skin surface Type de document : texte imprimé Auteurs : Doerte Segger, Auteur ; Uwe Aßmus, Auteur ; Michael Brock, Auteur ; Jessica Erasmy, Auteur ; P. Finkel, Auteur ; Andreas Fitzner, Auteur ; Helgard Heuss, Auteur ; Uta Kortemeier, Auteur ; Sven Munke, Auteur ; Thomas Rheinländer, Auteur ; H. Schmidt-Lewerkuhne, Auteur ; Werner Schneider, Auteur ; Gabriele Weser, Auteur Année de publication : 2007 Article en page(s) : p. 107-110 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'pH naturel 'Peau humaine' 'Avant-bras' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Characterization of the skin's natural state is very important for understanding skin functions and describing disturbances of skin function. In the field of cosmetics and dermatologicals the natural pH of the skin surface plays an important role in the development of products with a skin neutral pH. In a multicenter study the natural pH of the skin surface (exception of underarm and genital areas), was to be measured. It was to be determined whether gender-specific differences in the pH occur. The skin surface pH was measured on the inside of the forearms in 222 volunteers (147 female, 75 male) using the skin pH meters of the respective institutes. The pH was measured in triplicate on adjacent areas 24 h after the last contact of the measuring site with water, topical applications and an intensive washing procedure. The values of the skin surface pH were 4.9 (arithmetic mean). The 95% interval was between 4.1 and 5.8. The pH on the forearm of the male volunteers was slightly lower than that of the females. The difference was statistically significant (p < 0.01; 4.8 to 5.0). The authors suggest that the GDCh recommendations for the claims »skin neutral pH«, »ideal pH« or »skin-friendly pH« should be revised and propose a pH range of 4.1 to 5.8 for the main body areas excluding the underarm and genital areas. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10419
in IFSCC MAGAZINE > Vol. 10, N° 2 (04-05/2007) . - p. 107-110[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 007989 - Périodique Bibliothèque principale Documentaires Disponible N° 266 - 01/2015 - Les grandes questions de notre temps (Bulletin de SCIENCES HUMAINES) / Héloïse Lhérété
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Titre : N° 266 - 01/2015 - Les grandes questions de notre temps Type de document : texte imprimé Auteurs : Héloïse Lhérété, Directeur de publication, rédacteur en chef Année de publication : 2015 Importance : 94 p. Présentation : ill. Format : 29 cm Prix : 6,90 E Tags : Monde Gouvernance Mondialisation Guerres 'Extrémisme religieux' Démocratie Santé Energie 'Croyance religieuse' Bonheur 'Développement personnel' Sport Travail Identité Société Inégalités Institutions Education Famille Ecole Solidarité 'Vie professionnelle' 'Cause animale' Technologies Internet Neurosciences Culture 'Evolution humaine' Idéologie Index. décimale : 301 Sociologie : Classer ici les ouvrages d'ensemble sur la société, L'anthropologie sociale et culturelle à 306, physique à 573 Note de contenu : - MONDE : Qui gouverne le monde ? - Vers un nouvel âge de la globalisation ? - A quoi ressemblent les nouvelles guerres ? - Qu'est-ce que le jihad ? - La démocratie survivra-t-elle au 21e siècle ? - Faut-il ouvrir les frontières ? - Santé : le tournant global ? - Quelle énergie pour demain ?
- SOCIETE : Comment construire une société de confiance ? - Pourquoi les inégalités augmentent-elles ? - Une France coupée en deux ? - Faut-il craindre le gouvernement des juges ? - A quoi sert l'école ? - Pourquoi la famille est-elle redevenue aimable ? - Peut-on se passer d'autorité ? - Travail : l'âge du faire ? - L'économie de partage, une alternative au capitalisme ? - Vie professionnelle, vie privée : le brouillage ? - Quelle éthique pour les animaux
- INDIVIDUS : Peut-on vivre sans Dieu ? - Que faire de nos vulnérabilités - Le bonheur, une valeur sûre ? - Développement personnel : pourquoi un tel succès ? - Le sport, un exercice spirituel ? - S'épanouir au travail : une utopie ? - Peut-on choisir son identité sexuelle
- SCIENCES ET CULTURE : Les algorithmes ont-ils pris le pouvoir ? - Quelle régulation pour le web ? - Les objets connectés vont-ils révolutionner la médecine ? - Les neurosciences expliquent-elles tout ? Les séries télévisées nous rendent-elles meilleurs ? - Quelle évolution pour Homo sapiens ? - Quel humanisme pour notre temps ?Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=bulletin_display&id=15522 [n° ou bulletin]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 16708 - Périodique Bibliothèque principale Documentaires Disponible