[article]
| Titre : |
Androgenetic alopecia : Microbiota landscape and role of lindera strychnifolia roots extract as a natural solution for hair loss |
| Type de document : |
texte imprimé |
| Auteurs : |
Edith Filaire, Auteur ; A. Dreux, Auteur ; Carine Boutot, Auteur ; F. Volat, Auteur ; Edwige Ranouille, Auteur ; Justine Demangeon, Auteur ; Jean-Yves Berthon, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 16-22 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Alopécie
Champignons microscopiques
Cheveux -- Croissance
Cheveux -- Soins et hygiène
Cosmétiques
Cuir chevelu -- Soins et hygiène
Extraits de plantes:Extraits (pharmacie)
Microbiote
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The human scalp harbors a vast community of microbiotal mutualists. Androgenetic alopecia (AGA), a most common form of hair loss in males, is a multifactorial condition involving genetic predisposition and hormonal changes. The role of microflora during hair loss remains to be understood. Here, we investigated bacterial communities in 12 healthy and 12 AGA subjects at baseline and after 84 days of treatment by Lindera strychnifolia roots extract (LsR). Using a phototrichogram, we also compared hair density and total hair counts in 17 subjects receiving LsR treatment at baseline and after 83 days of treatment.
The analysis of bacterial distribution at the genus level showed no modifications between healthy and AGA groups. Higher C. acnes/S. epidermidis ratio in AGA subjects compared to control ones was noted. Concerning the mycobiota environment, lower abundance of Basidiomycota and higher proportion of Ascomycota, associated with lower proportion of Malassezia genus and increase of other fungal genus (Wallemia, Eurotium), implicated in the hair loss process, were observed in AGA scalp. Finally, lower proportion of M. globosa and M. restricta were observed. Therefore, data from sequencing profiling of the scalp microbiota strongly support a different microbial composition between normal and AGA affected the scalp. 84 days treatment with LsR extract rebalances bacteriota and mycobiota for a healthy scalp. A significant increase in hair number that reach +6.9 % compared to Day 0 (p=0.002) was observed in the 17 subjects. At this time point, 71 % of men had an improvement of hair density. Based on these results, we conclude that the LsR extract is a promising remedy for preventing hair loss and promoting hair growth. |
| Note de contenu : |
- MATERIALS AND METHODS : Preparation of extract - Subjects recruitment - Treatment
- RESULTS : Identification of bacteria communities - Identification of fungal communities - Effect of LsR extract treatment on microbiome - Phototrichogram test - Self-assessment
- Fig. 1 : Distribution of the bacterial genus present in the samples corresponding to healthy and hair loss/chronic alopecia subjects
- Fig. 2 : Ratio C. acnes/S. epidermidis at D0 in healthy and hair loss scalp
- Fig. 3 : Distribution of the fungal phyla and genus present in the samples corresponding to healthy and hair loss/chronic alopecia subjects
- Fig. 4 : Effect of LsR extract on the ratio C. acnes/S. epidermidis
- Fig. 5 : Mean variation of hair number in type III alopecia after application of LsR extract. *** p=0.002 vs D0
- Fig. 6 : Effect of LsR extract on the ratio C. acnes/S. epidermidis |
| En ligne : |
https://drive.google.com/file/d/1r-WpGzzf4nBlANwlX7oEnNP2Bd-st9KO/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34063 |
in SOFW JOURNAL > Vol. 146, N° 5 (05/2020) . - p. 16-22
[article]
|
Aller sur edunet
Accueil
Ajouter le résultat dans votre panier Affiner la rechercheAméliorer la flore cutanée avec des bactéries d'origine végétale in EXPRESSION COSMETIQUE, N° Hors-série (12/2021)
