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Testing the Discriminative Capacity of Compartmental Modeling for the Analysis of the In-Vivo Epidermal Water Content Changes Following Topical Application under Occlusion / Pedro Contreiras Pinto in IFSCC MAGAZINE, Vol. 5, N° 2 (04-05-06/2002)
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Titre : Testing the Discriminative Capacity of Compartmental Modeling for the Analysis of the In-Vivo Epidermal Water Content Changes Following Topical Application under Occlusion Type de document : texte imprimé Auteurs : Pedro Contreiras Pinto, Auteur ; Luis Marcelo Pereira, Auteur ; Rui Minhos, Auteur ; Luis Monteiro Rodrigues, Auteur Année de publication : 2002 Article en page(s) : p. 87-92 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Skin hydration' 'efficacy testing' 'mthematical modeling' POST 'in-vivo measurement' evaporation 'dynamic water loss' TEWL Index. décimale : 668.5 Parfums et cosmétiques Résumé : Mathematical modeling of cutaneous variables is an attratictive strategy to meet the compex nature of in-vivo skin, especially in the presence of an external stimulus such as a topical product. Despite the oversimplification implied, meeting the conceptualization of the model with the representative (physiological) variables is still a major difficulty, often impairing the model validity.
Once achieved, however, its applicability will mostly depend on the demonstration of the accuracy and practicability of the model. In previous works, the authors developed a bi-compartmental model designed to dynamically describe the Trans-epidermal water loss(TEWL) curves obtained in-vivo from the Plastic Occlusion Stress Test (POST) methodology. Occlusion was performed in healthy human volunteers (n=10) occluded with either 10% glycerin in water solution or water alone. Desorption curves allowed to obtain kinetic parameters such as k(evap)(the water evaporation rate at skin surface), t1/2 evap(the evaporation half-life), and DWM (the dynamic water mass) allowing a detailed quantitative description of the hydration process. Results demonstrate that the proposed model is adequate to identify significant differences (p<0.05) between the curve profiles, revealing the different hydration mechanisms involved, and suggesting an interesting application potential for the substantiation and efficacy testing of cosmectics.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10649
in IFSCC MAGAZINE > Vol. 5, N° 2 (04-05-06/2002) . - p. 87-92[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003874 - Périodique Bibliothèque principale Documentaires Disponible Bring back the steel ? The growth of plastics in automotive applications / Rose Ann Ryntz in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol. 3, N° 1 (01/2006)
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Titre : Bring back the steel ? The growth of plastics in automotive applications Type de document : texte imprimé Auteurs : Rose Ann Ryntz, Auteur Année de publication : 2006 Article en page(s) : p. 3-14 Note générale : Bibliogr. Langues : Américain (ame) Tags : 'Flow agents' 'Dynamic mechanical properties' Fluorescence Hardness 'Scratch resistance' 'UV spectroscopy' Photodegradation Polyacrylics Isocyanates 'Melamine-formaldehyde resins' Photostabilizers Polyurethanes Solventborne 'UV, EB radiation cure' Waterborne 'Service life prediction' Weatherability Automotive-OEM High-solids Latex PARP Index. décimale : 667.9 Revêtements et enduits Résumé : The development of plastics has evolved from the use of natural materials to the use of chemically modified natural materials and, finally, to completely man-made molecules. Plastics continue to improve, to afford flexibility, high-impact, and strength. In automotive applications, plastics have increased in utilization to comprise approximately 10% of the total vehicle weight. They offer increased ductility, freedom from corrosion, and increased styling capability. Although plastics have had a remarkable impact on our culture, it is obvious that there is a price to be paid for their use. Plastics are almost too good, as they are durable when processed correctly, but easily damaged when utilized in the incorrect application. Plastics also degrade very slowly, making recycling mandatory. And finally, while plastics consume only 4% of the world's oil production (petroleum is the raw material that is chemically altered to form commercial plastics), their cost hinges on the cost of petroleum. As petroleum prices increase, so too will the cost of plastic. In 2004, the higher price of plastic forced many plastic manufacturers out of business, and forced many automotive suppliers to look into alternative replacements. With publications such as USA Today reporting that current oil reserves will only last 40 years, scientists continue to seek cheaper alternatives to plastic. This article summarizes the history of commercial plastic development, with a focus on utilization of the materials in automotive applications. Damage criteria of plastic components, namely scratch, oxidative degradation, and impact, are discussed in relation to coatings and processing robustness. Environmental regulations, particularly in relation to recycling mandates, are explained. And finally, trends in alternative material development, including bioplastics, films, ceramic coatings, and nano-composites, are formulated. DOI : 10.1007/s11998-006-0002-9 En ligne : https://link.springer.com/content/pdf/10.1007%2Fs11998-006-0002-9.pdf Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=3708
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Code-barres Cote Support Localisation Section Disponibilité 003762 - Périodique Bibliothèque principale Documentaires Disponible