| Titre : |
A critical review of techniques and technology of tablet coating |
| Type de document : |
texte imprimé |
| Auteurs : |
Nana Satpute, Auteur ; Ganesh Zade, Auteur |
| Année de publication : |
2022 |
| Article en page(s) : |
p. 70-77 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Comprimés
Enrobage (technologie)
Enrobage pharmaceutique
Evaluation
Fluidisation
Liants
Pigments
Plastifiants
Polymères
Revêtements organiques
solvants
|
| Index. décimale : |
667.9 Revêtements et enduits |
| Résumé : |
Pharmaceutical drug coatings are highly advantageous and considerable development has recently happened to enhance the quality of the tablet. Tablet coating is carried out for the purposes such as decoration and protection of tablets along with some functional properties. The coating is a homogeneous mixture of polymeric material ; a very thin layer is applied on a substrate of the drug by using various techniques. These coatings techniques are either manually operated or fully automated. The automatic process gives coating with more uniform film properties at a high production rate. The coating is the last unit operation in the manufacturing of drugs in the pharmaceutical industries. Tablet coating involves the use of various binders, colour forming agents (colorants), organic solvents and plasticizers to get the required characteristics. Coating a tablet is always a great challenge to coating a formulator as it involves various statutory requirements to qualify as well as technically it also performs well against various environmental changes. Coating plays a key role in the pharma industry to protect the drugs from different environmental challenges like changes in humidity, light, heat etc. Now a days in coating application industries various new coating techniques are available like spray and fluidised bed methods that are developed to overcome the limitations of old techniques. This review paper focuses on the various aspects of various raw materials, types of tablet coating, processes of tablet coatings, defects and remedies of tablet coatings etc. |
| Note de contenu : |
- PURPOSE OF COATING THE TABLET
- TABLET COATING MECHANISM : Types of coatings - Sugar coating
- FILM COATING
- RESIN
- PIGMENTS : Requirements of good pigment
- PLASTICIZER
- SOLVENT : Requirements of good solvent - Advantages of film coating over sugar coatings - Tablet coating defects and remedies - Colour variation - Orange peel - Blooming - Twinning - BListering/pinholes - Cracking - Chipping
- EVALUATION OF TABLET COATING
- ASPECTS OF TABLE COATING CHARACTERISATION
- Fig. 1 : Electrostatic dry coating system
- Fig. 2 : Classification of pigments
- Fig. 3 : Film coating process flow diagram |
| En ligne : |
https://drive.google.com/file/d/10h7iu-swNzc7oRVBjKC-cWyRuyx732mn/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38539 |
in PAINTINDIA > Vol. LXXII, N° 10 (10/2022) . - p. 70-77
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