The influence of age, gender and race/ethnicity of the composition of the human axillary microbiome / M. Li in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 41, N° 4 (08/2019)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 41, N° 4 (08/2019) . - p. 371-377 Titre : The influence of age, gender and race/ethnicity of the composition of the human axillary microbiome Type de document : texte imprimé Auteurs : M. Li, Auteur ; A. E. Budding, Auteur ; M. van der Lugt-Degen, Auteur ; L. Du-Thumm, Auteur ; M. Vandeven, Auteur ; Aixing Fan, Auteur Année de publication : 2019 Article en page(s) : p. 371-377 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Âge Aisselles Femmes Groupe ethnique Hommes Microbiome cutané Transpiration Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The microbial community plays an important role in the generation of human axillary odour by transforming odourless natural secretions into volatile odorous molecules. A limited number of traditional culturing methods and molecular based research have been performed to characterize the human axillary microbiome in small collection sample sizes. Moreover, only a few have considered the interpersonal variations across age, gender or race/ethnicity, and none have included all three variables within one single study. The aim of this study was to characterize the axillary microbiome of healthy subjects across different age groups, genders and races/ethnicities in a large sample size. - Methods : The underarm skin swab samples were collected from 169 healthy subjects. The axillary microbiome was analysed by IS‐pro, a clinically validated high‐throughput DNA fingerprinting technique. - Results : The results indicate that the senior subjects (55+) tend to have a higher number of total bacterial than younger adults (of a defined age). The diversity of odour causing bacteria, e.g. corynebacteria, increases with age. Among the three races/ethnicities studied, East Asians have a unique microbial composition compared to Caucasians and Hispanics, which may contribute to the different odour profiles observed among the races/ethnicities studied. - Conclusion : Human axillary microbiome varies by age, gender and race/ethnicity. This study has provided an unprecedented fundamental knowledge about the axillary microbiota as a function of age, gender and race/ethnicity. Note de contenu : - MATERIALS AND METHODS : Subject recruitment - Sample collection - IS-profiling of axillary microbiota and data analysis - RESULTS : Overall diversity of human axillary microbiome - Age effect on human axillary microbiome - Gender effect on the human axillary microbiome - Race/ethnicity effect on the human axillary microbiome DOI : 10.1111/ics.12549 En ligne : https://drive.google.com/file/d/1HL6JX5m_QbjAPdK9oHUZ0x88HyxQ7USd/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=33116 [article]

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The potential prebiotic effect of 2-Butyloctanol on the human axillary microbiome / Min Li in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 6 (12/2021)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 6 (12/2021) . - p. 627-635 Titre : The potential prebiotic effect of 2-Butyloctanol on the human axillary microbiome Type de document : document électronique Auteurs : Min Li, Auteur ; Katie Truong, Auteur ; Shyamala Pillai, Auteur ; Thomas Boyd, Auteur ; Aixing Fan, Auteur Année de publication : 2021 Article en page(s) : p. 627-635 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : 2-butyloctanol Aisselles -- Soins et hygiène Corynébactéries Cosmétiques Déodorants Microbiote Prébiotiques Staphylocoques Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The human axilla is colonized by a wide array of microorganisms that contribute to the generation of body odour. Traditional antiperspirant/deodorant products are used to reduce perspiration in the axillary region and to treat or prevent the growth of bacteria in this region, thereby reducing or eliminating body odour. However, they may also compromise the axillary microbiome balance. The personal care industry has been seeking new ingredients, such as prebiotics or probiotics, to maintain a healthy balance of the skin microbiome by inhibiting odour-causing bacteria, whilst maintaining and promoting the growth of good bacteria. The aim of this study was to investigate the prebiotic effect of a skin-care ingredient, 2-butyloctanol, on the human axillary microbiome. - Methods : An in vitro growth inhibition/promotion assay was performed to test whether 2-butyloctanol inhibited or promoted skin bacterial growth. The impact of 2-butyloctanol on the axillary microbiome was also investigated in a human clinical study using 16S rRNA gene sequencing. - Results : In-vitro testing showed that 2-butyloctanol significantly inhibited the growth of corynebacteria at concentrations of 0.64%, 2.56% and 5.12%, whilst the growth of Staphylococcus epidermidis was maintained at the same concentrations. The impact of 2-butyloctanol on the axillary microbiome was also validated in a human clinical study. A deodorant roll-on product containing 3% of 2-butyloctanol significantly reduced the relative abundance of corynebacteria, whilst increasing the relative abundance of Staphylococcus and the ratio of Staphylococcus to corynebacteria after four weeks of application, whilst the placebo showed no significant change. Conclusion : For the first time, it was demonstrated that 2-butyloctanol had a potential prebiotic effect on the human underarm microbiome in inhibiting odour-causing Corynebacterium, whilst maintaining and promoting skin-friendly Staphylococcus in both in-vitro and in-vivo studies. Therefore, 2-butyloctanol could be used as a potential prebiotic ingredient in personal care products for underarm microbiome protection. Note de contenu : - MATERIALS AND METHODS : Growth inhibition/promotion assay - Clinical study design - Bacterial qPCR - 16S rRNA gene sequencing - 16S rRNA gene sequencing data analysis - Statistical analysis - RESULTS : Growth inhibition/promotion assay - Bacterial qPCR - 16S rRNA gene sequencing DOI : https://doi.org/10.1111/ics.12738 En ligne : https://drive.google.com/file/d/1B3bWhmhY8M52miG0w0DfH_eg9fXsPUHA/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37045 [article]

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