Bacterial skin microbiota/microbiome investigation / Fabrice Perin in PERSONAL CARE EUROPE, Vol. 12, N° 4 (09/2018)  

[article]  inPERSONAL CARE EUROPE > Vol. 12, N° 4 (09/2018) . - p. 65-68 Titre : Bacterial skin microbiota/microbiome investigation Type de document : texte imprimé Auteurs : Fabrice Perin, Auteur ; Kunyanatt Chalothorn, Auteur ; Preeyanuch Tachalerdmanee, Auteur Année de publication : 2018 Article en page(s) : p. 65-68 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Dermatologie Flore cutanée Microbiologie Microbiome cutané Microbiote Index. décimale : 668.5 Parfums et cosmétiques Résumé : We have almost reached the point where we can characterise nearly exhaustively the bacteria inhabiting the skin and microbiome research has already improved our understanding the pathogenesis of some disease. However many questions still remain. Firstly, we are not assured to really understand of what defines a healthy microbiota. Scientists have started to find associations of some skin diseases or particular skin conditions with particular microbial species but the causality relationship is often not demonstrated yet. Secondly, little is known about the persistance of bacterial populations, the causes and consequences of their time fluctuations. We know virtually nothing about most metabolites that are produced by skin bacteria in vivo, even though these are the key molecules responsible for the cross-talks between microbes and their human host. This point is of utmost importance since we have to decipher the mechanistic bases (particulary the chemical signals) for interactions between members of microbial communities and their hosts or the mechanisms that underlie associations between specific skin area and their respective microbiota. Next generation high-throughput sequencing and development of novel bioinformatics approaches will certainly help to fill these gaps in our knowledge of microbiome physiological effects. Then, we will have a chance to be able to modulate particular bacteria within the skin microbiota community, to use probiotics to modify the gut microbiome to achieve 'beauty from within' objectives, to manipulate host-microbial homeostasis without risking to create unforessen adverse outcome. Rational microbiome-based interventions using local application of selected bacteria or topical treatments modulating bacterial activity could thus become an essential tool in the field of personalised cosmetic and medical treatments. For instance, the feasibility of microbiome-based skin diagnosis has already been proven for psoriasis patients. Note de contenu : - Microbiota of healthy and diseased skin - Designing skin microbiome studies - Fig. 1 : Relative proportions of the bacteria versus human cells and the microbiome versus genes. Bacteria hosted by the body outnumber human cells by a factor of 10 and that the microbiome has 150 times more genes than the human body does - Fig. 2 : Conducting a microbiome study step by step : 1) samping of skin microbial community ; 2) extraction of DNA ; 3) amplification and sequencing using the 16S-based approach or whole genome shotgun (WGS) metagenomic sequencing ; 4) taxonomic classification, community composition and functions En ligne : https://drive.google.com/file/d/1lpFxiBUxw39cQAb5eKy2lyiH9XWjSWMH/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=31144 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
20195	-	Périodique	Bibliothèque principale	Documentaires	Disponible

L-Cystine + L-Glutathione : efficacy for an even complexion / Joël Duperray in PERSONAL CARE EUROPE, Vol. 13, N° 4 (09/2019)  

[article]  inPERSONAL CARE EUROPE > Vol. 13, N° 4 (09/2019) . - p. 49-53 Titre : L-Cystine + L-Glutathione : efficacy for an even complexion Type de document : texte imprimé Auteurs : Joël Duperray, Auteur ; Renaud Sergheraert, Auteur ; Kunyanatt Chalothorn, Auteur ; Preeyanuch Tachalerdmanee, Auteur ; Fabrice Perin, Auteur Année de publication : 2019 Article en page(s) : p. 49-53 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Agents de blanchiment Dermo-cosmétologie Etudes cliniques Evaluation Mélanogénèse Peau -- Soins et hygiène Taches pigmentaires (dermatologie) Index. décimale : 668.5 Parfums et cosmétiques Résumé : The quest for means to get a beautiful skin is endless. However, defining what is beautiful partially depends on the geographical and ethnic origins of the persons. For instance, having a white skin is an extremely important element of the women's beauty in Asian culture. The desire for white skin originally cornes from traditional Asian values and beliefs. This desire has also been reinforced by Western influences (for instance Caucasian models are often used in adverts for European or American cosmetic brands sold in Asian countries). That is the reason why whitening/lightening products are among the best-selling products in the Asian cosmetic industry and are also becoming very important in Middle East, Africa and South America. In these areas, for many people, hyperpigmentation and skin pigmentary spots are not only considered as aesthetic problems, but they are also synonymous of decreased self-esteem, premature skin ageing and may facilitate the occurrence of skin damages, exacerbated by sun exposure. Conversely, Caucasians are looking to tan their skin since many consider tanning as a marker of a healthy lifestyle. But recent global consumer surveys on the primary cosmetic concerns of women have identified uneven skin tone and age spots as major concerns relative to signs of ageing. Trying to maintain or to regain a uniform skin tone, clear of age spots, is therefore a major and shared objective to consumers worldwide. Note de contenu : - Clinical study - Anti-pigmentary spots effect - Skin lightening effect - Self-assessment - Tolerance - Fig. 1 : Simplified representation of melanin biosynthesis. The putative mechanism of the lightening action of Cysti-White is that the oral supplement accelerates the synthesis rate of pheomelanin whilst slowing down eumelanin production. - Fig. 2 : Oral supplementation with L-Cystine as a source of cysteine to increase glutathione production. - Fig. 3 : Evolution of the mean pigmentary spot size after 45 days and 90 days of daily use of the four tested oral formulations, compared to baseline. - Fig. 4 : Twice daily oral intake of L-Cystine + L-Glutatione supplement during 12 weeks visually reduce the pigmentary spot on face. - Fig. 5 : Evolution of the mean Individual Typological Angle ITA° determined on the cheek (top) and on the lower forearm (bottom) after 45 days and 90 days of daily use of the four tested oral formulations, compared to baseline. - Fig. 6 : Twice daily oral intake of Cysti-White during 12 weeks visibly lightens the facial skin. - Fig. 7 : Mean percetentages of agreements with some statements after 90 days of use of the tested oral supplements. Mechanisms regulating melanogenesis. En ligne : https://drive.google.com/file/d/15ZViNMGuXrM1RzJd1bN6BeywOmc7pCqq/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=33150 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
21143	-	Périodique	Bibliothèque principale	Documentaires	Disponible

---

1 (1 - 2 / 2)