| Titre : |
First cannabis sativa stem cells : nourishing microbiota |
| Type de document : |
texte imprimé |
| Auteurs : |
Oscar Expósito, Auteur ; Alejandro Guirado, Auteur ; Daniel Robustillo, Auteur ; Ana Gallego, Auteur ; Maria Mas, Auteur ; Pau Riera, Auteur ; Daniel Luna, Auteur ; Sara Laplana, Auteur ; Tarik Ruiz, Auteur ; Sandra Ruiz, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 37-40 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge:Antirides
Biomolécules actives
Cannabis et constituants
Caractérisation
Cellules souches
Clarté de la peau
Etudes cliniques
Ingrédients cosmétiques
Microbiote
Neurones sensitifs
Ocytocine
Peau -- Soins et hygiène
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The skin microbiota and the brain are connected through an existing natural pathway where the microbiota is the first step.
The new active Kannabia SensePLF (INCI name: Cannabis Sativa Callus Lysate), is the first generation of Cannabis sativaplant stem cells and introduces the concept of in situpostbiotic. Through its mechanism of action, the active modulates the skin commensal microbiota to produce a positive in situ postbiotic cocktail that ignites the synthesis of happiness related neurochemicals from the skin that connects with the brain, turning into a wellbeing response and a healthier and stronger skin. Several in vitroand in vivotrials have been carried out to demonstrate the skin well-ageing effect, positive brain activation and modulation of mood state thanks to the active ingredient. |
| Note de contenu : |
- The microbiota-skin brain axis
- The concept of in situ postbiotic
- The first cannabis sativa stem cells
- In vitro efficacy
- In vivo efficacy : In vitro 1 : Characterisation of the bacterial in situ postbiotic - In vitro 2 : Analysis of the microbiota-skin-brain axis networks - Oxytocin levels in keratinocytes (NHEK - step 4) - Oxytocin levels in sensory neurons
- In vivo efficacy : In vivo 1 : Evaluation of skin well-ageing effect - Mood wrinkles (marionette & frown lines) - Skin hydration - Skin radiance - In vivo 2 : Evaluation of the emotional modulation - Analysis of the brain activation by functional Magnetic Resonance Imaging (fMRI) - Modulation of mood state
- Fig. 1 : Microbiota-skin-brain axis
- Fig. 2 : Analysis of the microbiota-skin-brain axis networks
- Fig. 3 : Oxytocin levels in NHE
- Fig. 4 : Oxytocin levels in sensory neurons
- Fig. 5 : Clinical evaluation of wrinkles
- Fig. 6 : 3D brain model and correlation coefficient matrices
- Fig. 7 : Clinical evaluation of the brain activation by fMRI |
| En ligne : |
https://drive.google.com/file/d/1vTklSb6UDWGSLMWTqov3tT9R5ALJfD7S/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34277 |
in PERSONAL CARE EUROPE > Vol. 14, N° 3 (06/2020) . - p. 37-40
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First cannabis sativa stem cells : nourishing microbiota in PERSONAL CARE EUROPE, Vol. 14, N° 3 (06/2020)
