[article]
| Titre : |
Nano or non-nano the key aspect of the measurement method |
| Type de document : |
texte imprimé |
| Auteurs : |
Myriam Sohn, Auteur ; Wendel Wohlleben, Auteur ; Philipp Müller, Auteur ; Denis Botin, Auteur ; Marcel Schnyder, Auteur ; Stanislaw Krus, Auteur ; Stephanie Acker, Auteur ; Bernd Herzog, Auteur |
| Année de publication : |
2022 |
| Article en page(s) : |
p. 2-9 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cosmétiques
Dioxyde de titane
Formulation (Génie chimique)
Granulométrie
Ingrédients cosmétiques
Mesure
Microscopie électronique en transmission
Nanoparticules
Oxyde de zinc
Produits antisolaires
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Despite the UV performance benefits of particulate UV filters, concerns have been raised over their potential percutaneous permeation leading to the requirement of a specific approval for all nano UV filters in Europe. Under the legally binding definition of the Cosmetic regulation No. 1223/2009, nanomaterial means […] a material […] on the scale from 1 to 100 nm. The recommendation of the European Commission (2011/696/EU) revised 10 of June 2022 (2022/C229/01) further specifies that a material is nano when at least 50% of the number size distribution of the constituent particles is comprised between 1 and 100 nm. The situation for Titanium Dioxide and Zinc Oxide is confusing since the constituent particles are often part of agglomerates. Some suppliers clearly specify the nano feature of their material, while others declare the non-nano property of their inorganic products. The objective of this study was, therefore, to measure the number-based particle size distribution of three marketed Titanium Dioxide and Zinc Oxide grades using the decision support flow scheme devised by the NanoDefine project. This group was created to support the identification of nanomaterials as required by the European legislation. We employed the tier 1 method asymmetrical flow field-flow fractionation (AF4) coupled with UV and IC-PMS (inductively coupled plasma mass spectroscopy) detectors and tier 2 method transmission electron microscopy (TEM). The study clearly taught that the samples that appeared to be non-nanomaterials with AF4-IC-PMS measurements were finally proven to be nanomaterials using the TEM tier 2 method. Relying only on tier 1 methodologies such as AF4, X-Ray Disc Centrifuge or Dynamic Light Scattering to determine the non-nano property of a material is insufficient, since tier 1 methods are not able to detect constituent particles as part of agglomerates, which is often the case for Titanium Dioxide and Zinc Oxide. The status of being a non-nanomaterial can, in this case, only be certified with a tier 2 technique, particularly electron microscopy. |
| Note de contenu : |
- MATERIALS AND METHODS : Samples of inorganic UV filters - Sunscreen market product - Particle size measurement methods
- RESULTS : Asymmetrical flow field-flow fractionation - Transmission Electron MIcroscopy |
| En ligne : |
https://drive.google.com/file/d/1cR6X6diZiXzgjg00_rZyAvVldN9PMu8l/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37924 |
in SOFW JOURNAL > Vol. 148, N° 7/8 (07-08/2022) . - p. 2-9
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