3D modelling of Malassezia furfur skin interaction / Valérie Borrel in GLOBAL PERSONAL CARE, Vol. 23, N° 10 (11/2022)  

[article]  inGLOBAL PERSONAL CARE > Vol. 23, N° 10 (11/2022) . - p. 51-53 Titre : 3D modelling of Malassezia furfur skin interaction Type de document : texte imprimé Auteurs : Valérie Borrel, Auteur ; Antoine Florin, Auteur ; Maëlle Garion, Auteur ; Christel Boudry, Auteur ; Michel Salmon, Auteur Année de publication : 2022 Article en page(s) : p. 51-53 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Dermatite sébhorrhéique Dermatologie Epiderme Expression génique Malassezia Marqueurs biologiques Modélisation tridimensionnelle Relations hôte-champignon Index. décimale : 668.5 Parfums et cosmétiques Résumé : Straticell illustrates in a 3D model that Malassezia furfur invades the upper layers of the reconstructed epidermis with deleterious impacts on the barrier function, inducing an effective immune and inflammatory response, at both gene and protein levels. Malassezia furfur is a lipid-dependent yeast naturally living on the skin. Despite its tolerance by the immune system under healthy condition, M. furfur overgrowth is associated with skin disorders such as dandruff. Dandruff and its more severe form seborrheic dermatitis (SD), are common chronic inflammatory conditions characterized by an abnormal shedding of the skin in seborrheic areas of the body. While dandruff is restricted to the scalp, SD also affects oily rich areas of the face, causing itching, pruritic lesions and erythema. Environmental and internal stress factors, dysregulation of the immune system and fungal colonization are amongst the main contributors to the development of SD and dandruff.1 It has been described that in dandruff, the quantity of Malassezia can increase up to 1.5 to 2 times its normal level. This huge spread of yeast highly invades the epidermis, with detrimental consequences on the skin barrier function. Because the epidermis is the principal barrier against the penetration of chemicals and pathogens, any disruption increases microbial invasion and triggers both innate and acquired immune response. Keratinocytes are playing a central role in this response by secreting key signaling molecules like antimicrobial peptides to overcome pathogenic infections, as well as various cytokines and interleukins to recruit inflammatory cells. In the case of Malassezia overgrowth, previous studies have reported the expression of some defensins and pro-inflammatory cytokines in response to infection. Note de contenu : - Colonization of RHE with M. furfur and barrier disruption - Impact on gene expression - Secretion of protein biomarkers En ligne : https://drive.google.com/file/d/1zmSouLpZxhh3o0d_hPimbYgbku4otzBA/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38707 [article]

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Anti-inflammatory and scalp care efficacy of a multi-herb extraction against malassezia furfur / Yina Lu in SOFW JOURNAL, Vol. 147, N° 11 (11/2021)  

[article]  inSOFW JOURNAL > Vol. 147, N° 11 (11/2021) . - p. 6-11 Titre : Anti-inflammatory and scalp care efficacy of a multi-herb extraction against malassezia furfur Type de document : texte imprimé Auteurs : Yina Lu, Auteur ; Jun Tian, Auteur Année de publication : 2021 Article en page(s) : p. 6-11 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Anti-inflammatoires Biomolécules actives Cosmétiques Cuir chevelu -- Soins et hygiène Dermatite sébhorrhéique Dermatites fongiques Dermo-cosmétologie Eczéma constitutionnel Essais (technologie) Malassezia Index. décimale : 668.5 Parfums et cosmétiques Résumé :  Malassezia furfur is a lipophilic and dermatological pathogenic yeast, which normally exists on human skin, and causes tinea versicolor, seborrhoeic dermatitis, and atopic dermatitis, especially on human scalp. The multi-herb extraction VGP which consists of Vitex trifolia fruit, Gentiana scabra, and Polygonum multiflorum root extract was used to study its effect of anti-inflammation, controlling sebum and dandruff on scalp care. Results showed that on the model of NHEK and THP1 cell inflammation induced by Malassezia furfur, VGP can inhibit the expression of interleukin 6 (IL-6), prostaglandin E2 (PGE-2), monocyte chemoattractant protein 1 (MCP-1) and interleukin 1β (IL-1β) in a dose-dependent manner under 0.01% to 0.125% concentration. On the inflammatory model of 3D reconstructed skin induced by H2O2, VGP significantly improved the cell viability and skin structure, and reduced the production of interleukin 8 (IL-8), PGE-2, and leukotriene B4 (LTB4). During 4 week’s treatment with test shampoo contained 0.5% VGP thrice a week on 16 subjects met with different symptom, VGP reduced the sebum content and TEWL, improved the redness, itching and dandruff on human scalp skin. Therefore, as a natural active ingredient VGP can play a role in scalp care and skin care by targeting inflammation. Note de contenu : - MATERIALS AND METHODS : VGP preparation - Maintenance of cells - Anti-inflammatory experiments on cells - Anti-inflammatory experiments on 3D reconstructed skin - Scalp care test in vivo - Statistical analysis - RESULTS : Anti-inflammatory efficacy of VGP against M. furfur on cells - VGP inhibited the inflammation and cell damage on reconstructed skin - VGP reduced the itching and redness of human scalp skin En ligne : https://drive.google.com/file/d/1fHsMXBQzG3UwovFof_wsjz_WoYMRYdbR/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=36987 [article]

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Enhanced piroctone olamine retention from shampoo for superior anti-dandruff efficacy / Eric S. Johnson in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° 2 (03-04/2023)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° 2 (03-04/2023) . - p. 236-245 Titre : Enhanced piroctone olamine retention from shampoo for superior anti-dandruff efficacy Type de document : document électronique Auteurs : Eric S. Johnson, Auteur ; Debora W. Chang, Auteur ; James R. Schwartz, Auteur ; Ulrike Blume-Peytavi, Auteur ; James P. Henry, Auteur ; Tamara L. Caterino, Auteur ; Allison L. Talley, Auteur Année de publication : 2023 Article en page(s) : p. 236-245 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antifongiques Antipelliculaires Cheveux -- Soins et hygiène Cosmétiques Cuir chevelu Dermatite sébhorrhéique Desquamation Etudes cliniques Pellicules (dermatologie) Piroctone olamine Produits capillaires shampooings Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Background : Dandruff is a pervasive chronic condition which negatively impacts quality of life. Effective treatment requires efficient delivery of scalp benefit agents that control commensal scalp Malassezia levels. Delivery of benefit agents from shampoos requires balancing many technical parameters to achieve the desired outcome without sacrificing secondary parameters, such as cosmetic attributes. - Objectives : To develop formulation technologies that increase the shampoo delivery efficiency of the scalp benefit agent piroctone olamine (PO). Increased delivery should result in increased anti-dandruff efficacy. - Methods : Micellar Stability and Association parameters were quantified via dynamic surface tension and nuclear magnetic resonance (NMR) diffusion parameters, respectively. PO delivery has been assessed in vivo both on the scalp surface and follicular infindibula using extraction procedures and analytical analysis. Clinical anti-dandruff efficacy was assessed for an advanced delivery technology prototype in comparison to standard delivery technology. - Results : Shampoo prototypes have been developed that increase the delivery efficiency of PO. Both surfactant and polymer coacervate-based approaches have been developed. Decreased micellar stability results in weaker association between PO and micelles, resulting in more efficient PO retention on the scalp surface and delivery to the infundibula. Increased charge density of cationic polymers optimizes coacervation enabling improved PO delivery as well. Increased PO delivery has been shown clinically to result in higher anti-dandruff efficacy as measured by both visible flakes and underlying biomarkers. - Conclusion : Increased efficiency PO delivery shampoos have been developed by optimization of both surfactant and coacervate parameters. The increased deposition efficiency results in significantly more products with significantly greater anti-dandruff efficacy. Note de contenu : - MATERIALS AND METHODS : Shampoo products and compositions evaluated - Measurement of Micellar Stability parameter (θ) - Measurement of Micellar Association parameter (Ds/Da) - Measurement of scalp surface retention of piroctone olamine in vivo - Measurement of infundibular delivery of piroctone olamine in vivo - Clinical efficacy study design - Assessment of flaking severity - Assessment of histamine and ratio of IL1ra/IL-1α from scalp surface - Test products - Statistical analysis - RESULTS : Micellar Stability parameter evaluations - Micellar Association parameter (Ds/Da) - Scalp surface retention of piroctone olamine in vivo - Infundibular delivery of piroctone olamine in vivo - Evaluation of Anti-Dandruff clinical efficacy - Table 1 : Summary of shampoo compositions evaluated - Table 2 : Summary of Micellar Stability parameter and Micellar Association parameter data - Table 3 : Summary of Micellar Association data and PO retention - Table 4 : Summary of piroctone olamine scalp retention data - Table 5 : Summary of anti-dandruff clinical evaluation DOI : https://doi.org/10.1111/ics.12835 En ligne : https://drive.google.com/file/d/15x6UeCPskFUzXhclO36lFCI1b11GE8SC/view?usp=share [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39173 [article]

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Infant skin conditions - treatments and products / Danny McCamlie in PERSONAL CARE EUROPE, Vol. 7, N° 5 (09/2014)  

[article]  inPERSONAL CARE EUROPE > Vol. 7, N° 5 (09/2014) . - p. 92-93 Titre : Infant skin conditions - treatments and products Type de document : texte imprimé Auteurs : Danny McCamlie, Auteur Année de publication : 2014 Article en page(s) : p. 92-93 Langues : Anglais (eng) Catégories : Dermatite sébhorrhéique Erythèmes Nourrissons Peau -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : Infant skin has been consistently shown to be of higher sensitivity and of lower tolerance of irritants. It shows lower barrier functionality and is therefore more susceptible to external influences, affected by a variety of unique situations and conditions which can upset and disrupt the infant's comfort. Industry trends which can be monitored by Aspen Clinical show that the trend is for better prevention in the development of conditions specific to an infant's situations. En ligne : https://drive.google.com/file/d/1AdLFC-n1OQv5zSlCxz2-pmtW-myCKoIS/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=22031 [article]

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Irritated, itchy, scaly, seborrheic scalp / Liki von Oppen-Bezalel in SOFW JOURNAL, Vol. 148, N° 7/8 (07-08/2022)  

[article]  inSOFW JOURNAL > Vol. 148, N° 7/8 (07-08/2022) . - p. 24-29 Titre : Irritated, itchy, scaly, seborrheic scalp : Causes and relief with a proprietary, cold-pressed nigella sativa (black seed) oil, standardized to 3% thymoquinone Type de document : texte imprimé Auteurs : Liki von Oppen-Bezalel, Auteur ; Julie S. Jurenka, Auteur Année de publication : 2022 Article en page(s) : p. 24-29 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antimicrobiens Cuir chevelu -- Soins et hygiène Dermatite sébhorrhéique Dermo-cosmétologie Huiles et graisses végétales Ingrédients cosmétiques Nigella sativa et constituants La nigelle cultivée (Nigella sativa L. 1753) ou cumin noir est une espèce de plante annuelle de la famille des Renonculacées originaire du sud-ouest de l'Asie. Les graines sont utilisées comme remède traditionnel ou comme épice dans de nombreux pays du monde - Synonymes : Herbe aux épices, Cheveux de Vénus, Barbe des Capucins, Patte d'Araignée, Barbiche, Cheveux d'Ange. Les graines de cumin noir sont aussi appelée "poivrette". - Composition chimique : Les graines de nigelle cultivée contiennent des lipides, protéines, acides aminés, glucides (ou extrait non azoté, ENA), et des métabolites secondaires en quantité bien moins grande : terpénoïdes, polyphénols, alcaloïdes, acides organiques, tanins, des saponines, mucilage, des fibres et des vitamines. Les graines de cumin noir contiennent une forte teneur en huile grasse (31 %) constituée d'ester du glycérol des acides linoléique, oléique et palmitique. Avec en outre, des phospholipides, glycolipides, tocophérols, stérols et surtout les dérivés phénoliques actifs que sont la thymoquinone, la thymohydroquinone, et le thymol. La nigella sativa contient des saponosides, des composés phénoliques et des alcaloïdes. On obtient également de l'huile essentielle de nigelle par distillation à la vapeur d'eau de l'huile végétale obtenue par première pression à froid. - Activités pharmacologiques : Elle possède des composés antioxydants, anti-inflammatoires, sédatifs, contre l'hypertension, antivirales, contre la covid-19, contre l'obésité, le diabète de type 2, des propriétés antitumorales, antibactériennes et antifongiques. - Toxicologie : La toxicité de la nigelle est pratiquement nulle en ce qui concerne la consommation des graines, de l'huile ou de l'extrait aqueux.Seules la thymoquinone et l'huile essentielle possèdent une toxicité chez la souris en injection intrapéritonéale. Cependant, il manque encore des études sur la tolérance cutanée, la mutagénicité et le potentiel de toxicité de l'huile essentielle lorsqu'elle est absorbée par voie orale. (Wikipedia) Index. décimale : 668.5 Parfums et cosmétiques Résumé : Medicinal herbs have been used as natural healing and cosmetic remedies since ancient times. The annual flowering plant, Nigella sativa, its black seeds and oil derived from them were used for medicinal and beauty routines since the ancient Egyptian pharaohs and queens. It has been studied more recently for its many health and cosmetic, anti-inflammatory, antioxidant, and antifungal benefits. To harness the power of the Nigella sativa (black seed) oil (BSO), its active constituent, thymoquinone, and their demonstrated benefits, a patent pending, cold-pressed, full-spectrum black seed oil, standardized to 3% thymoquinone and very low FFAs was developed. Branded as B’utyQuinâ„¢ for cosmetic use, BSO has been studied in vitro to determine the mechanisms responsible for skin disorders such as, irritated, itchy, scaly skin and scalp and seborrheic dermatitis. The studies included BSO’s antimicrobial effects on microorganisms such as Malassezia furfur, Candida albicans and Staphylococcus aureus, often associated with such disorders. This has been followed by clinical research to establish efficacy, safety and compatibility of BSO as a topical active ingredient for the scalp. BSO’s ability to positively impact the irritated, itchy, scaly scalp associated with seborrheic dermatitis has been revealed. In a blinded, controlled clinical trial in subjects with mild to moderate seborrheic dermatitis, topical application of scalp serum with 5% B’utyQuin for 28 days resulted in significant improvements in scalp oiliness, irritation, itchiness, scaling, and overall health of the scalp as compared to baseline. Note de contenu : - Seborrheic dermatitis - Black seed oil - In vitro research - Clinical research study - Clinical results discussion - Table BSO compositions for antimicrobial benefits En ligne : https://drive.google.com/file/d/1l7mbrFJWpNjACp412L3XnrE5FEQ41Yoe/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37927 [article]

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A novel ingredient with 3R effect targeting impure skin in SOFW JOURNAL, Vol. 142, N° 5 (05/2016)  

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