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Une première étape vers le lean dans les entreprises de sous-traitance mécanique (retour sur 7 ans de pratique) / Romain Real in REVUE FRANCAISE DE GESTION INDUSTRIELLE, Vol. 29, N° 1/2010 (03/2010)
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Titre : Une première étape vers le lean dans les entreprises de sous-traitance mécanique (retour sur 7 ans de pratique) Type de document : texte imprimé Auteurs : Romain Real, Auteur ; Magali Pralus, Auteur ; Maurice Pillet, Auteur ; Ludovic Guizzi, Auteur Année de publication : 2010 Article en page(s) : p. 71-86 Note générale : Bibliogr. Langues : Français (fre) Catégories : Efficience dans l'industrie
Production -- Contrôle
Production -- GestionTags : Lean 'Toyota Production System' 'Amélioration continue' Accompagnement 'PME du décolletage' Index. décimale : 338.06 Efficacité de la production Résumé : Les exigences de compétitivité croissantes conduisent les entreprises à revoir leurs systèmes de production. Un nombre important d'entreprises se tourne alors vers le Toyota Production System et le Lean. Ces approches novatrices conduisent à des résultats impressionnants en recherchant autant l'élimination des gaspillages que l'amélioration continue. Nous présentons dans cet article la première partie d'une étude de sept années d'accompagnement collectif basé sur le Lean dans les PME de la Vallée de l'Arve, spécialisées dans le décolletage. Malgré la simplicité apparente des principes du Lean, l'étude montre la difficulté d'arriver à des résultats durables pour les entreprises ciblées. Nous faisons ici une analyse critique des résultats obtenus et discutons des premières solutions. DOI : https://doi.org/10.53102/2010.29.01.619 Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=9659
in REVUE FRANCAISE DE GESTION INDUSTRIELLE > Vol. 29, N° 1/2010 (03/2010) . - p. 71-86[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 012267 - Périodique Bibliothèque principale Documentaires Disponible Development and application of intelligent drug delivery systems in dermatology and cosmetics / Sylvia Marton in IFSCC MAGAZINE, Vol. 6, N° 1 (01-02-03/2003)
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Titre : Development and application of intelligent drug delivery systems in dermatology and cosmetics Type de document : document électronique Auteurs : Sylvia Marton, Auteur ; Gabriella Csoka, Auteur ; Istvan Racz, Auteur Année de publication : 2003 Article en page(s) : p. 29-36 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques
Dermatologie
Dermo-cosmétologie
Diffusion (physique)Tags : 'Cholesteryl oleyl carbonate' 'Intelligent drug delivery system' Melotose 'Pulsatile 'Responsive Thermoresponsability 'TTS patch' Index. décimale : 668.5 Parfums et cosmétiques Résumé : The development of new intelligent drug delivery systems is a relatively recent technology. Sometimes, it is a requirement to liberate the active material while symptoms develop and continue to exist. For such purposes self-regulated, responsive, pulsatile systems are ideal. Several new polymeric auxiliary materials have appeared and in this article new manufacturing processes are presented to produce thermoresponsive intelligent drug delivery systems using these materials. The types, the development and application of devices in dermatology and cosmetics are discussed with special attention to the production, characterization and testing of some types of transdermal therapeutic soft-patch systems (membrane-controlled, matrix-controlled). The matrix and the film were produced from Metolose, a cellulose derivative, whereas the thermoresponsive property was achieved via the use of cholesteryl oleyl carbonate (COC).
The « on-off » state-realized by the sol-gel transition or smetic to cholesteric, cholesteric-isotropic liquid phases changes –was tested by static and dynamic methods by changing the temperature. Attention was given to the fact that the presence of inappropriate auxiliary material may destroy and cancel pulsatile drug delivery due to absorption or incompability.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10615
in IFSCC MAGAZINE > Vol. 6, N° 1 (01-02-03/2003) . - p. 29-36[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003878 - Périodique Bibliothèque principale Documentaires Disponible Polymeric ester technology - an effective delivery concept for sun and skin care / D. Smith in IFSCC MAGAZINE, Vol. 3, N° 3 (07-08-09/2000)
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Titre : Polymeric ester technology - an effective delivery concept for sun and skin care Type de document : texte imprimé Auteurs : D. Smith, Auteur ; A. O'Connor, Auteur ; D. Young, Auteur ; R. Siegfried, Auteur Année de publication : 2000 Article en page(s) : p. 21-30 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques
Polyesters
Produits antisolairesTags : 'Alpha hydroxy acids' Desquamation 'Gas chromatography' Sunscreens 'Topical delivery system' Dihydroxyacetone 'Skin whiteners' Hydroquinone 'Lactic acid' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Several years ago we discovered that polyesters mitigate skin penetration of organic UV absorbers. Our initial research explored the effect of polyester structure on its’ ability to focus and maintain organic UV absorbers in the outer stratum corneum (SC) of skin. Delivery technologies that can mitigate skin penetration of UV absorbers, as polyester technology has been proven to do, are of interest to formulators and marketers of sunscreens. Current market trends favor products with SPF ratings above 15 and the inclusion of UV absorbers in “daily-wear” products, increasing both the level and duration of exposure to UV absorbers. Clinical studies that the Personal Care Application Group had commissioned with sunscreen actives, indicated that polyesters facilitate retention of up to 95% of applied organic UV absorbers in-vivo. Polyesters have also been shown to increase the solubility of oxybenzone, improve coupling of actives, and enhance SPF efficiency and effectiveness. Through our research, we were able to gain a better understanding of the relationship between polyester structure and skin penetration. With this knowledge, we gained ability to design and synthesize polyesters into which specific polarity actives could partition.
The next phase of our research focused on screening and optimizing polyesters to maximize benefits derived from the application of water-soluble active ingredients, such as alpha hydroxy acids. Hydroxy acids are generally thought to improve the appearance of skin via reduction in corneocyte adhesion leading to accelerated exfoliation and an increase rate of SC cell renewal. Effectiveness of hydroxyl acids could be maximized if distributed and maintained throughout the entire SC. By maintaining hydroxyl acids in the SC, contact with viable cells in the dermis is minimized, thereby reducing their potential for sensory stinging and irritation. We found that with the incorporation of polyesters, a reduced level of AHA can be utilized with efficacy of the hydroxyl acid maintained, thereby lowering the irritation potential attributed by the hydroxy acid.
For the AHA research, a series of polyesters with varied structural characteristics were formulated in emulsions containing the hydroxy acid, lactic acid. The effect of these formulations on human skin was examined in-vivo using a comparative cytology method determining the change in squamous cell size at weekly intervals over twenty-eight days. Results indicate specific polyesters are useful in optimizing and sustaining delivery of lactic acid. Preliminary panels studies suggest that polyesters also reduce the potential for lactic acid to sting and cause irritation.
Other hydrophilic actives were our polyester technology. A preliminary investigation was also conducted on the ability of polyesters to enhance delivery to dihydroxyacetone ( DHA), which is the most widely used sunless tanning ingredient. These experiments suggest that the color persistence and color intensity attributed to DHA is enhanced when used in combination with specific, select polyesters. Hydrophilic skin whitening activities are a popular market trend, and were also investigated with our polyester technology. The two skin whitening actives utilized for our studies were hydroquinone and lactic acid. Lactic acid has been found to elicit a skin whitening response. Clinical in-vivo panel tests were conducted to access the ability of the polyesters to enhance the performance attributed by these skin-whitening agents.
Based on the results of the AHA, DHA, and skin whitening experiments, coupled with the ability to synthesize polyesters with regard to an active ingredient’s solubility parameters, polyesters have proven to be effective controlled delivery systems for hydrophilic as well as lipophilic actives.
Note de contenu : - EXPERIMENTAL - MATERIALS AND METHODS : Evaluation of lipophilic sunscreen actives with polyesters - Evaluation of hydrophilic actives with polyesters - Formulas used in comparative cytology method for AHA performance criteria - Conduct of panel for comparative cytology study - Test formulations used in dihydroxyacetone (DHA) study - Skin whitening test formulations - Hydroquinone test formulation - Lactic acid skin whitening formulation - Conduct of hydroquinone skin whitening study.
- RESULTS : Polyesters with lipophilic organic sunscreen actives - Polyesters with hydrophilic actives - Skin whitening study with hydroquinone - Skin lightening with lactic acid.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10806
in IFSCC MAGAZINE > Vol. 3, N° 3 (07-08-09/2000) . - p. 21-30[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 004649 - Périodique Bibliothèque principale Documentaires Disponible