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Heat shock response and UV protection / Friedhelm Steckel in IFSCC MAGAZINE, Vol. 2, N° 1 (01-02-03/1999)
[article]
Titre : Heat shock response and UV protection : a study of heat shock proteins in cultured human skin cells Type de document : texte imprimé Auteurs : Friedhelm Steckel, Auteur ; Dieter Pollet, Auteur ; Ramon Gieseler, Auteur ; U. Hoppe, Auteur Année de publication : 1999 Article en page(s) : p. 17-22 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Heat shock proteins' 'UV radiation' Photodamage 'DNA damage' protection' Index. décimale : 668.5 Parfums et cosmétiques Résumé : In the studies presented here, the induction of heat shock proteins (HSP) in cultured human skin cells were investigated. Furthermore, the protective effect of a heat shock response towards the damaging action of UV irradiation on fibroblasts was examined. Intracellular HSP72 protein levels were quantified using a flow-c ytometer after immunostaining and damaged cells were identified 24h post UV-exposure by their nuclear fluorescence after staining with propidium iodide. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10851
in IFSCC MAGAZINE > Vol. 2, N° 1 (01-02-03/1999) . - p. 17-22[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 008184 - Périodique Bibliothèque principale Documentaires Disponible What is the most suitable strategy for stress proteins in cosmetics? / Christine Jeanmaire in IFSCC MAGAZINE, Vol. 6, N° 3 (07-08-09/2003)
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Titre : What is the most suitable strategy for stress proteins in cosmetics? Type de document : texte imprimé Auteurs : Christine Jeanmaire, Auteur ; Vincent Bardey, Auteur ; Louis Danoux, Auteur ; Philippe Moser, Auteur ; Philippe Moussou, Auteur ; Gilles Pauly, Auteur Année de publication : 2003 Article en page(s) : p. 221-226 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Cytoprotection 'Heat shock proteins' Pollution Skin 'Skin defense' Stress UV Index. décimale : 668.5 Parfums et cosmétiques Résumé : Under various stress conditions, heat shock protein expression is enhanced in cells. Working on skin pieces, two of the major skin-expressed heat shock proteins, HSP72 and HSP27, were visualized by immunohistochemistry after several stress conditions (UV, pollutants, thermal shocks) and the heat shock protein expression quantified in the epidermis. A strong increase of the epidermal heat shock protein expression, due to these different stresses, was observed. The most suitable cosmetic strategy is discussed: does one need to prevent or to favor heat shock protein induction in cutaneous cells?
A prevention strategy is suitable in the case of acute stress, such as severe UV exposure that provokes cell damage and a strong induction of heat shock proteins. It is demonstrated that, using a photoprotective active ingredient Sunactyl®, suppression of the heat shock protein expression of cells is linked to a protection of the cells against UV induced damages.
An induction strategy is appropriate for chronic daily stress from various sources. Seeing that a small and controlled induction of heat shock proteins in the skin speeds up the response and enhances the cellular resistance to further stress, HSP-Balance® was developed, which boosts the heat shock protein induction in the skin under stress conditions.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10584
in IFSCC MAGAZINE > Vol. 6, N° 3 (07-08-09/2003) . - p. 221-226[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003880 - Périodique Bibliothèque principale Documentaires Disponible