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What is the most suitable strategy for stress proteins in cosmetics? / Christine Jeanmaire in IFSCC MAGAZINE, Vol. 6, N° 3 (07-08-09/2003)
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Titre : What is the most suitable strategy for stress proteins in cosmetics? Type de document : texte imprimé Auteurs : Christine Jeanmaire, Auteur ; Vincent Bardey, Auteur ; Louis Danoux, Auteur ; Philippe Moser, Auteur ; Philippe Moussou, Auteur ; Gilles Pauly, Auteur Année de publication : 2003 Article en page(s) : p. 221-226 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Cytoprotection 'Heat shock proteins' Pollution Skin 'Skin defense' Stress UV Index. décimale : 668.5 Parfums et cosmétiques Résumé : Under various stress conditions, heat shock protein expression is enhanced in cells. Working on skin pieces, two of the major skin-expressed heat shock proteins, HSP72 and HSP27, were visualized by immunohistochemistry after several stress conditions (UV, pollutants, thermal shocks) and the heat shock protein expression quantified in the epidermis. A strong increase of the epidermal heat shock protein expression, due to these different stresses, was observed. The most suitable cosmetic strategy is discussed: does one need to prevent or to favor heat shock protein induction in cutaneous cells?
A prevention strategy is suitable in the case of acute stress, such as severe UV exposure that provokes cell damage and a strong induction of heat shock proteins. It is demonstrated that, using a photoprotective active ingredient Sunactyl®, suppression of the heat shock protein expression of cells is linked to a protection of the cells against UV induced damages.
An induction strategy is appropriate for chronic daily stress from various sources. Seeing that a small and controlled induction of heat shock proteins in the skin speeds up the response and enhances the cellular resistance to further stress, HSP-Balance® was developed, which boosts the heat shock protein induction in the skin under stress conditions.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10584
in IFSCC MAGAZINE > Vol. 6, N° 3 (07-08-09/2003) . - p. 221-226[article]Réservation
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