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A novel system of removing décorin, a minor proteoglycan of bovine hides, to improve the quality of leather / Mila Aldema-Ramos in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA), Vol. CV, N° 7 (07/2010)
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Titre : A novel system of removing décorin, a minor proteoglycan of bovine hides, to improve the quality of leather Type de document : texte imprimé Auteurs : Mila Aldema-Ramos, Auteur ; Cheng-Kung Liu, Auteur Année de publication : 2010 Article en page(s) : p. 222-228 Note générale : Bibliogr. Langues : Américain (ame) Tags : Décorine Protéoglycane 'Enzymes protéolytiques' 'Dépilage oxydant' 'Hydroxyde de sodium' Percarbonate Index. décimale : 675 Technologie du cuir et de la fourrure Résumé : Décorin is a minor proteoglycan (part protein and part carbohydrate) of the skin that is among the key components that undergo changes and removal during conversion of hides to leather. The majority of décorin removal takes place during the dehairing of hides, either traditionally with sodium sulfide or by an alternative oxidative dehairing procedure. The oxidative dehairing method using sodium hydroxide and percarbonate, developed by Marmer and Dudley, was utilized. Further removal of décorin by exposure to proteolytic enzymes during pretanning was explored to study the effects on the quality of leather. Additional removal of décorin was observed when an alkaline protease was added during the reliming stage and pepsin was added during the pickling stage in the pretanning treatments of the hides. More pronounced improvement in leather quality, due to more decorin removed, was observed in oxidatively dehaired hides than those dehaired traditionally with sulfides. As the décorin content decreased, the leather product became softer, more stretchable, and tougher than the control leather tanned without adding proteolytic enzymes. Employing the alternative oxidative dehairing process can solve the problem of sulfide toxicity to the environment while at the same time improving the quality of leather if co-treated with proteolytic enzymes. En ligne : https://drive.google.com/file/d/14VZuMQ8i3iqZCzOoCDlZAS4yC_aiNJQp/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=9721
in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA) > Vol. CV, N° 7 (07/2010) . - p. 222-228[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 012329 - Périodique Bibliothèque principale Documentaires Disponible Versican expression by dermal papilla-regenerated hair follicles – a promising tool for hair-regrowth products / Jiro Kishimoto in IFSCC MAGAZINE, Vol. 7, N° 1 (01-02-03/2004)
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Titre : Versican expression by dermal papilla-regenerated hair follicles – a promising tool for hair-regrowth products Type de document : texte imprimé Auteurs : Jiro Kishimoto, Auteur ; Tsutomu Soma, Auteur ; Robert Burgeson, Auteur ; Toshihiko Hibino, Auteur Année de publication : 2004 Article en page(s) : p. 21-28 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Follicule pileux' Protéoglycane Versicane Régéneration Index. décimale : 668.5 Parfums et cosmétiques Résumé : Hair follicle stem cells and dermal papilla cells play essential roles in the cyclical hair regeneration process. However, compared with the recent progress of follicular stem cell research, detailed analysis of dermal papilla cells is virtually unknown. We have focused on a large chondroitin sulfate proteoglycan molecule, versican, and prove its pivotal role in hair follicle induction both in vitro and in vivo. First, we examined versican expression with hair cycling by in situ hybridization (mRNA) and immunohistochemistry (protein). Results clearly showed specific versican expression in anagen onset of dermal papilla cells implying a function role of versican in hair induction. We then generated transgenic lines with LacZ or green fluorescent protein reporter genes under a versican regulatory element (promoter) control, and confirmed dermal papilla-specific activation of the reporter. These transgenic lines were utilized to isolate the dermal papilla cell population by means of a fluorescent activated cell sorter.
While freshly isolated dermal papilla cells were able to induce hair growth in a skin reconstitution assay when grafted with undifferentiated epidermal cells, this ability and versican expression were rapidly lost during passages in culture. In order to examine the functional role of versican in hair growth induction, versican full-length cDNAs were transfected into inactive passaged dermal papilla cells. Impressively, this forced expression of versican molecules partially restored hair inductivity of dermal papilla cells in a skin reconstitution assay. These results demonstrated the pivotal role of versican in hair induction both in vitro and in vivo and will connect the missing link between the signal from dermal papilla cells to follicular stem cells, and initiation of hair regeneration. We have also shown that the hair growth-promoting compound, cyclosporin A, can upregulate versican expression implying the application of a novel screening approach for hair growth-promoting compounds by monitoring versican expression as an indicator.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10542
in IFSCC MAGAZINE > Vol. 7, N° 1 (01-02-03/2004) . - p. 21-28[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003882 - Périodique Bibliothèque principale Documentaires Disponible