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Innovative approach to control acne-prone skin / M.L. Và zquez-Gonzà lez in PERSONAL CARE EUROPE, Vol. 12, N° 2 (04/2018)
[article]
Titre : Innovative approach to control acne-prone skin Type de document : texte imprimé Auteurs : M.L. Và zquez-Gonzà lez, Auteur ; M. Cócerra, Auteur ; J. Nestor, Auteur ; G. RodrÃguez, Auteur ; R. Saldaña, Auteur ; Lucyanna Barbosa-Barros, Auteur ; O. López, Auteur Année de publication : 2018 Article en page(s) : p. 153-156 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons.
Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique...
Cosmétiques
Dermo-cosmétologie
Etude in vivo
Evaluation
Evaluation visuelle
Peau -- Soins et hygiène
StatistiquesIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Excessive sebum production can give rise to oily skin, shiny appearance, enlarged pores and favour the development of acne lesions. The care of acne-prone skin involves the use of harsh molecules, wash out and multi-step products that irritate the skin and limit user compliance. This study describes the development of a bicosome system that targets the epidermis and follicles to effectively deliver a sebostatic active compound and potentiate its effects on sebum production and acne lesion prevention. This is an alternative approach to that offered by current products, which can be included in the daily care of acne-prone skin. Note de contenu : - METHODOLOGY : Skin penetration studies - In vivo studies - Instrumental evaluation - Clinical evaluation - Statistical studies
- RESULTS AND DISCUSSIONS : Skin penetration studies - In vivo studies: assessment of sebum excretion - Prevention of acne lesions - Clinical evaluation: prevention of new acne lesions - Visual evaluation of the volunteers by the dermatologist - Tolerance study
- FIGURES : 1. Cryo-TEM (Transmission Electron Microscopy) image of a Bicosome showing internal disc structures and the surrounding vesicle. Bar ) 200nm - 2. Microscope images from skin samples treated with a control solution of niacimide labelled with fluorescein and skin samples treated with the bicomide system labelled with fluorescein - 3. Average sebum amount ± SE at different experimental days (0,15 and 30) during the treatment with bicomide - 4. Visiopor photographs of the skin under UV light from different volunteers before and after the treatment with bicomide - 5. Decreases of the average % area covered by porphyrins ± SE at different experimental times during the treatment with bicomide - 6. Reduction of acne lesions after 30 days using bicomide - 7. Evaluation of the level of acne evaluated by the dermatologist (n=20) - 8. Visioface macrophotographs of volunteers showing the evolution of relevant acne lesions before and after the use of bicomideEn ligne : https://drive.google.com/file/d/1LeQIgcjUyNV75AmoiPo2UdLbbDCOwDAz/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30468
in PERSONAL CARE EUROPE > Vol. 12, N° 2 (04/2018) . - p. 153-156[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 19931 - Périodique Bibliothèque principale Documentaires Disponible Multi-target delivery to eliminate dark spots / Mercedes Cócera in PERSONAL CARE EUROPE, Vol. 11, N° 2 (04/2017)
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Titre : Multi-target delivery to eliminate dark spots Type de document : texte imprimé Auteurs : Mercedes Cócera, Auteur ; R. Saldaña, Auteur ; Lucyanna Barbosa-Barros, Auteur ; Olga López, Auteur Année de publication : 2017 Article en page(s) : p. 137-142 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Agents de blanchiment
Evaluation
Peau -- Soins et hygiène
Pigmentation, Troubles de la
Tests d'efficacitéIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Bicowhite complex is a sophisticated Bicosome system that works by blocking the main processes involved in the formation of dark spots. The in vitro studies demonstrated that this product is able to decrease melanin content without damaging the skin structure. This effect is explained by the interaction between the innovative Bicosome mechanism and the skin, which allows for adequate delivery and protection of the skin structure. Bicowhite has been proven effective in decreasing skin melanin content even when skin is submitted to UV radiation, which indicates that treatment with this product could a lso be carried out in sunny seasons. The in vivo studies demonstrated that Bicowhite is highly effective and specific in depigmenting dark spots, whitening, brightening, unifying skin tone and also improving the appearance of wrinkles and fine lines. The proposed multi-target delivery strategy opens up new possibilities for treatment and resolves some of the most important limitations of whitening treatments, such as lack of active penetration, disruption of skin structures, irritation, non-specificity, seasonality of treatments and, finally, insufficient efficacy. All results considered, we conclude Bicowhite is an effective and advanced whitening/brightening active ingredient to be used in all seasons. Note de contenu : - Multi-target delivery strategy
- In vitro efficacy studies
- Protective effect on the skin structure
- Whitening activity in skin exposed to UV radiation
- In vivo efficacy studies
- Clinical evaluationEn ligne : https://drive.google.com/file/d/1G64ydHkomIuR0kiS6hdeDHTexFyiVlYx/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28352
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Code-barres Cote Support Localisation Section Disponibilité 18819 - Périodique Bibliothèque principale Documentaires Disponible