Cell-activating effects of a viniferin-enriched grapevine extract / Olaf Holtkötter in IFSCC MAGAZINE, Vol. 12, N° 2 (04-05/2009)

[article]  inIFSCC MAGAZINE > Vol. 12, N° 2 (04-05/2009) . - p.101-105 Titre : Cell-activating effects of a viniferin-enriched grapevine extract Type de document : texte imprimé Auteurs : Olaf Holtkötter, Auteur ; Claudia Jassoy, Auteur ; Andreas Bock, Auteur ; Marianne Waldmann-Laue, Auteur ; Frank JanBen, Auteur Année de publication : 2009 Article en page(s) : p.101-105 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Fibroblast  Collagen  contraction  Confocal  laser  microscopy  Resveratrol  Senescence Index. décimale : 668.5 Parfums et cosmétiques Résumé : Extracts of grapevine, especially in the fermented form of wine, are reported to exert beneficial effects to human health. Grapevine polyphenols are considered to be the main compounds responsible for this beneficial activity, and of these, resveratrol has been studied in most detail. Because of its antioxidant properties, resveratrol demonstrates cell protective characteristics, but it is also able to reduce cell proliferation and induce apoptosis, especially in cancer cells. Investigations on the effects of resveratrol on UVB irradiated primary keratinocytes and HaCats have demonstrated protective properties also in skin cells. Although grapevine extracts are routinely used as an active ingredient in skincare cosmetics, the activity of these extracts on skin, apart from that of resveratrol, is only poorly understood. Here the effects on skin cells of a grapevine extract enriched with the resveratrol dimer (epsilon)-viniferin were analyzed in vitro and in vivo. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=6099 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
011489	-	Périodique	Bibliothèque principale	Documentaires	Disponible

Cutaneous restructuration by apple seed phytosterols : from DNA chip analysis to morphological alteration / Thomas Doering in IFSCC MAGAZINE, Vol. 7, N° 4 (10-11-12/2004)

[article]  inIFSCC MAGAZINE > Vol. 7, N° 4 (10-11-12/2004) Titre : Cutaneous restructuration by apple seed phytosterols : from DNA chip analysis to morphological alteration Type de document : texte imprimé Auteurs : Thomas Doering, Auteur ; Olaf Holtkötter, Auteur ; Kordula Schlotmann, Auteur ; Claudia Jassoy, Auteur ; Dirk Petersohn, Auteur ; Armin Wadle, Auteur ; Marianne Waldmann-Laue, Auteur Année de publication : 2004 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Skin  equivalent'  'cDNA  microarray'  'hyaluronic  acid'  phytosterols  'anti-wrinkle'  'skin  elasticity' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Plant secondary metabolites such as flavonoids, isoflavones and phytosterols have been proposed as cosmetic ingredients displaying anti-aging effects. On the cellular level, however, the activity profiles of these ingredients are only partially understood. In this study we analyzed the effects of apple seed phytosterols on age-related structural and functional parameters using cell biochemical, molecular biological and bioengineering techniques. The expression of age-related genes was studied using skin equivalents and cDNA microarrays. Incubation of skin equivalents with apple seed phytosterols had significant consequences: (i) differential regulation of a set of genes associated with keratinocyte proliferation and differentiation, (ii) stimulation of hyaluronic acid synthesis, and (iii) increase of epidermal thickness. In vivo studies revealed that apple seed phytosterols improve skin elasticity and decrease skin roughness. In conclusion, apple seed phytosterols display distinct biological effects and significantly improve the structure and function of mature skin. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10481 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
003885	-	Périodique	Bibliothèque principale	Documentaires	Disponible

---

1 (1 - 2 / 2)