Catering to the skin of generation Z / Harald van der Hoeven in PERSONAL CARE EUROPE, Vol. 14, N° 3 (06/2020)  

[article]  inPERSONAL CARE EUROPE > Vol. 14, N° 3 (06/2020) . - p. 48-51 Titre : Catering to the skin of generation Z Type de document : texte imprimé Auteurs : Harald van der Hoeven, Auteur ; Heiko Prade, Auteur Année de publication : 2020 Article en page(s) : p. 48-51 Langues : Anglais (eng) Catégories : Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons. Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique... Antipelliculaires Dermo-cosmétologie Ingrédients cosmétiques Peau -- Soins et hygiène Pellicules (dermatologie) Prurits Séborrhée Tests d'efficacité Index. décimale : 668.5 Parfums et cosmétiques Résumé : Catering to the skin of Generation Z is complex, but possible when done right. CutiBiome CLR (MPM Complex) underwent multiple efficacy studies and was clearly shown to have potent effects on the most important dermatological features of sebum-related skin problems. It importantly reduces the likelihood of the formation of acne lesions and it was shown to have potent effects on the reduction of the oiliness of both skin in the face and the scalp. These effects were not just determined scientifically, they were also perceived by the volunteers in the studies. Similarly, MPM Complex was able to reduce the number of acne lesions and dandruff, both perceivably and proven by an expert grader. MPM Complex is a Cosmos approved active ingredient, meaning it is natural. Added to that, it is safe and leaves skin and scalp with a pleasant and comfortable feel. It solves problems which are common to Generation Z consumers. 80% of the volunteers in the dandruff study reported that they were inclined to buy the product with MPM Complex which they had been using in the past 4 weeks. This percentage was significantly lower for those volunteers who had been using the same formulation, but containing a benchmark ingredient and not MPM Complex. 80% reported a reduction of itching, a type of skin discomfort common to the skin and scalp of the generation Z consumer. MPM Complex caters to the skin of Gen Z’ers and shows perceivable and satisfactory results. It further ‘ticks all boxes’ which are important to them. It is our belief that MPM Complex leads to a satisfied Generation Z consumer, who will be loyal to the product and brand it is contained in. Note de contenu : - Anticipating changes in skin is a complex undertaking - Efficacy studies - in vivo assays - Dandruff - Fig. 1 : Increased sebum production is beneficial for virulent phylotypes of C. acnes - Fig. 2 : Virulent C. acnes phylotypes form a biofilm which clogs pores - Fig. 3 : Initiation of a vicious circle leading to acnes lesions - Fig. 4 : The development of acnes lesions - Fig. 5 : Effect on sebum production as determined with sebumeter - Fig. 6 : Effect on skin oiliness in the perception of the volunteers - Fig. 7 : Effect on number of papules, comedones and pustules - Fig. 8 : Effect on typical features associated with acne as perceived by the volunteers. - Fig. 9 : Assessment of reduction of dandruff on 3 volunteers with micro-camera (1.5% MPM Complex) - Fig. 10 : Results obtained with assessment of reduction of dandruff with micro-camera - Fig. 11 : Perceived reduction of scalp itchiness - Fig. 12 : Percentage of volunteers who would buy the tested product En ligne : https://drive.google.com/file/d/1bW1lQ_7Qjb66685tWUqNCkzsPRV0YUy1/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34279 [article]

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Epidermal overexpression of stratum corneum chymotryptic enzyme, skin inflammation, and itch / Lennart Hansson in IFSCC MAGAZINE, Vol. 5, N° 4 (10-11-12/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 4 (10-11-12/2002) . - p. 279-283 Titre : Epidermal overexpression of stratum corneum chymotryptic enzyme, skin inflammation, and itch Type de document : texte imprimé Auteurs : Lennart Hansson, Auteur ; Anders Bergman, Auteur ; Annelii Ny, Auteur ; Elisabeth Ekholm, Auteur ; Torbjorn Egelrud, Auteur Année de publication : 2002 Article en page(s) : p. 279-283 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Couche cornée Eczéma constitutionnel Peau -- Inflammation Peau -- Maladies Peptidases Prurits Psoriasis Index. décimale : 668.5 Parfums et cosmétiques Résumé : Identification of tissue-specific mechanisms involved in the pathophysiology of inflammatory skin diseases could offer new possibilities to develop effective therapies with fewer systemic effects. One of the major unmet dermatological problems is itch, which is poorly understood and often difficult to threat. Understanding skin specific targets to identify new technology to ameliorate inflammation and itching is an under researched area but should represent a major market opportunity for both the cosmetic and dermatological industries. Stratum corneum chymotryptic enzyme (SCCE) is a serine protease, which is involved in the proteolytic degradation of corneodesmosomes during desquamation and possibly the activation of pro-inflammatory cytokines such as interleukin-1beta. SCCE is preferentially expressed in cornifying epithelia. It is synthesised by keratinocytes, packaged into the lamellar granules and extruded into the intercellular spaces in the stratum corneum together with the barrier lipids. Here we report on increased epidermal expression of SCCE in psoriasis and atopic dermatitis ; two major chronic inflammatory diseases. In atopic dermatitis, which is often associated with allergic diseases such as rhinoconjunctivitis and asthma, itch is a major symptom. We also pretent our findings on transgenic mice expressing human SCCE in suprabasal epidermal keratinocytes that developed pathologic skin changes similar to the human inflammatory diseases with increased epidermal thickness, hyperkeratosis, dermal inflammtion, impaired barrier function and severe pruritus. These findings indicate that SCCE may be involved in the pathogenesis of inflammatory skin diseases and itch, and that it should be evaluated as potential targets for new therapies. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10628 [article]

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Next generation soothing agent for sensitive skin / Martina Herrmann in SOFW JOURNAL, Vol. 150, N° 5 (05/2024)

[article]  inSOFW JOURNAL > Vol. 150, N° 5 (05/2024) . - p. 14-19 Titre : Next generation soothing agent for sensitive skin Type de document : texte imprimé Auteurs : Martina Herrmann, Auteur ; Maria Reichenbach, Auteur ; Lili Baraton, Auteur ; Nathalie Chevrot, Auteur Année de publication : 2024 Article en page(s) : p. 14-19 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Anti-inflammatoires Avoine et constituants Cosmétiques Dermo-cosmétologie Extraits de plantes:Extraits (pharmacie) Peau -- Soins et hygiène Produits hydratants Prurits Sensibilité cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : Sensitive skin and accompanying multiple sensory skin symptoms such as itching, burning, tightness, and stinging are a globally relevant consumer issue that is still on the rise. In this article, we will discuss SymCalmin® Avena [INCI: Maltodextrin, Avena Sativa (Oat) Kernel Extract], a modern natural, COSMOS certified, skin microbiome-friendly, enriched oat extract standardized to 200-250 ppm of avenanthramides and its benefits to soothe sensitive skin by prevention of itch and improvement of skin comfort and hydration. Note de contenu : - MATERIALS AND METHODS : Preventions of Neurokinin-1 (NK-1) receptor activation in vitro - Instant itch relief in vivo - Skin soothing efficacy in vivo & visible skin redness reduction in vivo - Long-term dryness prevention in vivo - Long-term skin microbiome in vivo study - RESULTS : Prevention of Neurokinin-1 (NK-1) receptor activation in vitro and instant itch relief in vivo study - Skin soothing efficacy in vivo - Visible skin redness reduction in vivo - Long-term dryness prevention in vivo - Long-term skin microbiome in vivo study Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=41206 [article]

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Scalp soothing properties of Portulaca oleracea / Claudia Zappelli in GLOBAL PERSONAL CARE, Vol. 24, N° 1 (01/2023)  

[article]  inGLOBAL PERSONAL CARE > Vol. 24, N° 1 (01/2023) . - p. 39-43 Titre : Scalp soothing properties of Portulaca oleracea Type de document : texte imprimé Auteurs : Claudia Zappelli, Auteur ; Annalisa Tito, Auteur ; Marida Bimonte, Auteur ; Antonio Colantuono, Auteur Année de publication : 2023 Article en page(s) : p. 39-43 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiradicalaire Biomolécules actives Cuir chevelu -- Soins et hygiène Homéostasie L'homéostasie (du grec "hómoios", "similaire", et "stásis", "stabilité, action de se tenir debout") est la capacité que peut avoir un système quelconque (ouvert ou fermé) à conserver son équilibre de fonctionnement en dépit des contraintes qui lui sont extérieures. L'homéostasie est la maintenance de l'ensemble des paramètres physico-chimiques de l'organisme qui doivent rester relativement constants (glycémie, température, taux de sel dans le sang, etc.). Produits hydratants Prurits Sensibilité cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : Sensitive scalp is an extension of the concept of sensitive facial skin, and is associated with dry skin, reactivity to climatic/environmental factors, and topical agents. Vitalab’s scientists have harnessed the power of the medicinal plant Portulaca oleracea, developing an ingredient clinically tested for its efficacy to soothe the skin, reduce the perception of itch intensity for both skin and scalp, and restore the skin barrier function. The multifunctional ingredient improved cellular ability to scavenge free radicals, while reducing the release of pro-inflammatory messengers, helping to relieve sensitive-prone skin and scalp. Note de contenu : - The perks of Portulaca oleracea - Performance backed by science - Maintaining epidermal hydric homeostasis - Improving skin protection targeting redox imbalance - Decreasing discomfort messenger's release - Attenuating skin itchiness - Effect on skin comfort and soothing efficacy - Soothing and anti-itching effect on the scalp - Materials and methods : In vitro testing - Soothing effect on sensitized skin - Evaluation of the scalp itchiness flaking and hydration - Table 1 : Erythema value percentage variation after treatment application (T10 ; T30 ; T60) versus to - Table 2 : Wheal diameter percentage variation after treatment application (T30 ; T60) versus T10 En ligne : https://drive.google.com/file/d/1p7onNGphuxlonkrRuIbmiAn-kAO5j55-/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38773 [article]

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