Investigating the effect of the pH of foot care product formulations on pedal skin in diabetic and non-diabetic subjects / Andreas Fitzner in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° 4 (08/2023)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° 4 (08/2023) . - p. 524-538 Titre : Investigating the effect of the pH of foot care product formulations on pedal skin in diabetic and non-diabetic subjects Type de document : texte imprimé Auteurs : Andreas Fitzner, Auteur ; Katrin Knuhr, Auteur ; Marianne Brandt, Auteur ; Stephan Bielfeldt, Auteur Année de publication : 2023 Article en page(s) : p. 524-538 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques Humidité Justification de l'allégation Peau -- analyse Peau -- Soins et hygiène pH Pieds -- Soins et hygiène Produits hydratants Tests de sécurité Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The use of skin care formulations with acidic pHs is seen as an effective method to maintain the acidic mantel of the skin; however, because the skin pH varies depending on the area of the body and as data are lacking for the skin pH of the feet, there was a need to examine whether this assumption holds true for skin care formulations designed for the foot. Thus, three foot creams formulated with a neutral, acidic or alkaline pH were compared with each other as well as to an untreated control group in order to analyse their impact on skin pH, hydration and general skin condition. - Methods : An exploratory clinical investigation with 60 enrolled subjects, half of whom had a diagnosis of diabetes (type 1 or type 2), was undertaken. The investigation followed a randomized, double-blind, balanced incomplete block design (BIBD) including intra-individual comparison (before and after treatment). Evaluations of skin pH and hydration were carried out using a pH meter and a Corneometer respectively. Objective evaluation of skin condition for efficacy assessment was performed by a trained grader. For tolerability evaluation, objective and subjective dermatological assessments were performed. - Results : At the end of the treatment period, the skin pH was largely unchanged at five out of six of the test areas, with the mean value for each treatment group using test products showing similar fluctuations as the untreated control group. Furthermore, the skin condition parameters studied all improved by a comparable magnitude for each of the treatment groups using the test products, whereas the untreated control group experienced a worsening of the skin condition parameters. - Conclusions : The results of this investigation suggest that where the skin of the foot is concerned, the pH of skin care formulations has no (physiologically) relevant influence on the skin's pH in either diabetic or non-diabetic subjects. Furthermore, the expectation that acidic formulations would be more beneficial for the skin's condition was not found to hold true for the skin of the foot, as no significant difference was observed between the performance of the three test products investigated in this study. Note de contenu : - MATERIALS AND METHODS : Test products - Study design - Subjects - Procedures and assessments - RESULTS : Drop-outs, adverse reactions and deviations - Skin pH following product application - Skin hydration following product application - Objective and subjective evaluation of the condition of the skin following product application - Table 1 : Test product description - Table 2 : Allocation of measurements and test areas - Table 3 : Study schedule - Table 4 : Demographics of analysed subjects - Table 5 : Mean number of callus per treatment group DOI : https://doi.org/10.1111/ics.12861 En ligne : https://drive.google.com/file/d/1AMOS8WcVf-ad0FByOi371Dk_KBNBRu31/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39882 [article]

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