In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract / J. Manosroi in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 42, N° 6 (12/2020)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 42, N° 6 (12/2020) . - p. 622-631 Titre : In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract Type de document : document électronique Auteurs : J. Manosroi, Auteur ; C. Chankhampan, Auteur ; W. Kitdamrongtham, Auteur ; J. Zhang, Auteur ; M. Abe, Auteur ; T. Akihisa, Auteur ; W. Manosroi, Auteur ; A. Manosroi, Auteur Année de publication : 2020 Article en page(s) : p. 622-631 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Anti tyrosinase Antiâge Antioxydants Cosméceutique Etude in vivo Niosomes Peau -- Soins et hygiène Riz et constituants Statistique Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : To evaluate the anti-ageing activity of cream containing the methanolic purple glutinous rice extract loaded in niosomes. - Methods : The in vitro biological activities of the purple glutinous rice extracted by methanol maceration were determined. The extract loaded in niosomes and the cream containing the niosomes were developed. The in vivo anti-ageing activity in 20 human volunteers including skin hydration, pigmentation, roughness and elasticity after daily application for 28 days compared to at initial was evaluated by Corneometer, Mexameter, Visiometer and Cutometer, respectively. - Results : The purple glutinous rice extract showed free radical scavenging (SC50), lipid peroxidation inhibition (IPC50), metal ion chelating (CC50) and tyrosinase inhibition (IC50) values at 32.31 ± 1.28, 57.40 ± 2.12, 85.05 ± 5.43 and 43.89 ± 2.14 mg/mL which were 0.00031, 0.011, 0.0078 and 0.0016 times of the standards (0.01 ± 0.00, 0.62 ± 0.14, 0.66 ± 0.05 and 0.07 ± 0.01), respectively. The purple glutinous rice extract contained 0.35 µg of anthocyanin/1 mg of the extract determined by HPLC. After loaded in niosomes, the solubility of the extract was not only increased in various solvents, but also the chemical stability in different environments (weak base, reducing agent and acid salt) was improved. The cream formulation containing niosomes loaded with 1%w/v of the purple glutinous rice extract indicated the anthocyanin remaining percentages after 6 cycles of heating and cooling test at 52.28% of the initial. For in vivo anti-ageing activities, cream containing niosomes loaded with the extract gave significant decreased melanin index and skin roughness reduction of −14.05 and −9.95% of the initial, respectively. The % changes of the increased skin hydration, skin elastic extension and skin elastic recovery when applied on human volunteers’ skin with this formulation were +48.73, -24.51 and +35.98%, respectively. - Conclusion : The cream containing niosomes loaded with the 1%w/v methanolic purple glutinous rice extract gave not only the suitable in vitro antioxidant activity and physical stability of the active anthocyanin, but also the superior in vivo anti-ageing activity on human skin compared to the cream base and before application which can be further developed as a novel anti-ageing cosmeceutical product. Note de contenu : - MATERIALS AND METHODS : Materials - Preparation of the purple glutinous rice extract - Antioxidant activities - Tyrosinase inhibition assay - Physical characteristics of the niosomal dispersion - Preparation of cream containing niosomes loaded with the purple glutinous rice extract - Anti-ageing activities in human volunteers of cream containing niosomes loaded with the purple glutinous rice extract - Statistical analysis - RESULTS AND DISCUSSION : Antioxidant activities of the purple glutinous rice extract - Characteristics of niosomes loaded with the purple glutinous rice extract - Physical characteristics of cream containing niosomes loaded with the purple glutinous rice extract - Anti-ageing activities in human volunteers of cream containing niosomes loaded with the purple glutinous rice extract DOI : https://doi.org/10.1111/ics.12658 En ligne : https://drive.google.com/file/d/1tZ9AG6JtucAx9VZbquCRTcHbUJk6iU27/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35429 [article]

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