| Titre : |
Novel plant growth factor as cosmetic ingredient |
| Type de document : |
texte imprimé |
| Auteurs : |
Hisae Aoshima, Auteur |
| Année de publication : |
2023 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Barrière cutanée
Biomolécules actives
Couche cornée -- Teneur en eau
Dermo-cosmétologie
Facteur de croissance (biochimie)
Formulation (Génie chimique)
Ingrédients cosmétiques
Peau -- Soins et hygiène
Vitamines
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Vitamin C60 BioResearch Corporation has developed 2-aza-8-oxohypoxanthine (AOH) as the first plant growth factor to be used as a cosmetic ingredient under the trade name Repista®. AOH is found in edible plants in small quantities, so a method for producing AOH at an industrial level was developed, producing a high-purity (>99.9 %) product. Previous results of the cellular activating effect and DNA microarray studies suggest that the AOH active ingredient may improve skin barrier function by promoting epidermal turnover, differentiation, and maturation and by stimulating the metabolism of old skin cells. The results of the present long-term continuous use study of applying the AOH active ingredient lotion facial cosmetic to a group of healthy Japanese women showed an increase in stratum corneum water content in the AOH active ingredient-applied group after eight weeks. Transepidermal water loss (TEWL) in the AOH active ingredient-applied group decreased significantly. Furthermore, analysis of skin lightness revealed that the L* value of the AOH active ingredient lotion group increased significantly after eight weeks, while no statistical change was observed in the placebo lotion group. The increase in stratum corneum water content, decrease in TEWL, and increase in skin lightness were suggested to be due to the ability of the AOH active ingredient to improve skin barrier function. |
| Note de contenu : |
- Product information
- Clinical trial of the AOH active ingredient : Clinical trial forumlation - Selection of subjects - Clinical trial study - Skin lightness
- Safety evaluation of the AOH active ingredient
- Table 1 : Product information for the AOH active ingredient
- Table 2 : Composition of the clinical trial formulation
- Table 3 : Comparative results of various AOH safety tests
- Figure : Chemical structure of AHX, ICA and AOH |
| En ligne : |
https://drive.google.com/file/d/1b58VK3wLe95A-vg5Us13IUiVjsjgE9P1/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39414 |
in GLOBAL PERSONAL CARE > Vol. 24, N° 4 (04/2023)
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Novel plant growth factor as cosmetic ingredient in GLOBAL PERSONAL CARE, Vol. 24, N° 4 (04/2023)
