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Ajouter le résultat dans votre panier Affiner la rechercheThe effects of Areca Catechu L extract on anti-aging / Kun-Kook Lee in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 21, N° 4 (08/1999)
Titre : The effects of Areca Catechu L extract on anti-aging Type de document : texte imprimé Auteurs : Kun-Kook Lee, Auteur ; Jung-Do Choi, Auteur Année de publication : 1999 Article en page(s) : p. 285–295 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Cosmétiques
Peau -- Soins et hygièneTags : Elastase 'Anti-âge' 'Synthèse du collagène' 'Palmier à bétel' Inhibition Index. décimale : 668.5 Parfums et cosmétiques Résumé : The anti-aging effects of Areca catechu L extract (CC-516) on skin were investigate both in vitro and in vivo. The CC-516 has a high proportion of proline (13%) of free amino acid content. The inhibitory effect of CC-516 on the elastase exhibited 37 to 90% inhibition by 10 to 250 μg/ml concentration ; the IC values with 40.8 μg/ml for porcine pancreatic elastase (PPE) and 48.1 μg/ml for human leukocyte elastase (HLE), respectively. One of the effects of elastase is that it is known to reduce the number of elastin fibers at the level of the enzyme deposition. The number of elastin fibers was increased when we drift from the deposit number of elastase with 100 mg/ml of CC-516. CC-516 showed protection of elastic fiber against degradation by the enzyme in an ex vivo assay. The CC-516 increased proliferation of human fibroblast cell by 85% at 10 concentration, compared with control, whereas the increase by ascorbic acid was 50%. The collagen synthesis was increased by 40% at 10% concentration of CC-516. The treatment with CC-516 improved skin hydration, the skin elasticity, and skin wrinkles. From this study, we suggest that CC-516 can be used as a new anti-aging component for cosmetics. DOI : 10.1046/j.1467-2494.1999.196563.x En ligne : https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.196563.x Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26486
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 4 (08/1999) . - p. 285–295[article]Exemplaires
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Titre : The effects of Areca catechu L extract on anti-inflammation and anti-melanogenesis Type de document : texte imprimé Auteurs : Kun-Kook Lee, Auteur ; Jung-Do Choi, Auteur Année de publication : 1999 Article en page(s) : p. 275–284 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Piégeage des radicaux libres' Hyaluronidase Tyrosinase 'Anti-mélanogénèse' Antioxydants 'Palmier à bétel' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Ethanolic extract (CC-516) from Areca catechu L was prepared and its various biological activities were evaluated, CC-516 showed potent anti-oxidative, free radical scavenging, and anti-hyaluronidase activity. Anti-oxidative effect of CC-516 (IC : 45.4 μg/ml) was lower than butylated hydroxytoluene (IC : 5μg ml), but similar to tocopherol and higher than ascorbic acid. Especially, CC-516 exhibited relatively high free radical scavenging activity (IC : 10.2 μg/ml) compared to control. CC-516 inhibited effectively hyaluronidase activity (IC: : 416 μg/ml), showed inhibition in vivo on delayed hypersensitivity as well as croton-oil induced ear edema in mice when it was topically applied. These results strongly suggest that CC-516 may reduce immunoregulatory/inflammatory skin trouble. Also, from the results, we have elucidated that CC-516 showed anti-allergic and anti-cytotoxicity activity. The whitening effect of CC-516 shown by the inhibition of mushroom tyrosinase activity with IC of 0.48 mg/ml and of melanin synthesis in B16 melanoma cells. This study indicates that CC-516 is effective on anti-inflammatory/anti-melanogenesis, and can be used as a new agent for cosmetics. DOI : 10.1046/j.1467-2494.1999.196590.x En ligne : https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.196590.x Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26485
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 4 (08/1999) . - p. 275–284[article]Exemplaires
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