Effect of a cationising agent on the conventional reactive dyeing of cotton / M. Javaid Mughal in COLORATION TECHNOLOGY, Vol. 124, N° 1 (2008)  

[article]  inCOLORATION TECHNOLOGY > Vol. 124, N° 1 (2008) . - p. 62-65 Titre : Effect of a cationising agent on the conventional reactive dyeing of cotton Type de document : texte imprimé Auteurs : M. Javaid Mughal, Auteur ; M. Naeem, Auteur ; Ausaf Aleem, Auteur ; Rehana Saeed, Auteur ; Kamran Ahmed, Auteur Année de publication : 2009 Article en page(s) : p. 62-65 Note générale : Bibliogr. Langues : Anglais (eng) Index. décimale : 667.3 Teinture et impression des tissus Résumé : Cationisation of cotton is emerging as an effective tool that may help to solve the environmental problems associated with the dyeing of cotton with reactive dyes. The efficiency of the cationising agent CA200 has been investigated and was found to be more effective when compared with the usual method for reactive dyeing of cotton. Pretreatment of the cotton fabric with the cationising agent increases the rate of dyeing compared with the existing method of reactive dyeing. The colour yields, in terms of the Kubelka–Munk values as a function of the amount of dye fixed, showed that cationisation enhances the colour strength. It also improves the washing fastness, rubbing fastness and depth of shade. The positive environmental impact of this cationisation process is significant and the cationised cotton shows a similar fabric quality as with the normal dyeing process. DOI : 10.1111/j.1478-4408.2007.00122.x En ligne : http://onlinelibrary.wiley.com/doi/10.1111/j.1478-4408.2007.00122.x/pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=3141 [article]

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Formulation development and characterization of highly water-soluble drug-loaded extended-release pellets prepared by extrusion–spheronization technique / Muhammad Iqbal Nasiri ; Rabia Ismail Yousuf ; Muhammad Harris Shoaib ; Kamran Zaheer ; Tariq Ali ; Kamran Ahmed ; Faaiza Qazia ; Sohail Anwer in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol. 16, N° 5 (09/2019)  

[article]  inJOURNAL OF COATINGS TECHNOLOGY AND RESEARCH > Vol. 16, N° 5 (09/2019) . - p. 1351-1365 Titre : Formulation development and characterization of highly water-soluble drug-loaded extended-release pellets prepared by extrusion–spheronization technique Type de document : texte imprimé Auteurs : Muhammad Iqbal Nasiri, Auteur ; Rabia Ismail Yousuf, Auteur ; Muhammad Harris Shoaib, Auteur ; Kamran Zaheer, Auteur ; Tariq Ali, Auteur ; Kamran Ahmed, Auteur ; Faaiza Qazia, Auteur ; Sohail Anwer, Auteur Année de publication : 2019 Article en page(s) : p. 1351-1365 Note générale : Bibliogr. Langues : Américain (ame) Catégories : Ethylcellulose Extrusion sphéronisation Formulation (Génie chimique) Granulés plastiques Hydrochlorure d'itopride Médicaments Système de libération contrôlée (technologie) Index. décimale : 667.9 Revêtements et enduits Résumé : The objectives of current study were (a) to prepare extended-release plain (without polymers) and matrix pellets of itopride hydrochloride (ITP) by extrusion and spheronization technique, (b) to control the initial fast release of drug from the matrix pellets by coating using ethylcellulose, Eudragit® RL/RS100 (2:1), and Kollicoat® SR 30D, and (c) to investigate the influence of different types and concentration of coating polymers on release of highly water-soluble drug. The plain pellet contained microcrystalline cellulose and lactose without polymer, whereas matrix pellet formulations were composed of hydroxypropyl methylcellulose (HPMC K4M, K15M, and K100M) and ethylcellulose (EC 7 cps). Matrix pellet formulations failed to control the drug release, up to targeted period of 12 h. Five pellet formulations—one without polymer (F1) and one from each polymer category (F4, F7, F10, and F13)—were screened out for coating using different types and levels of polymers. The DDSolver (an add-in software for MS Excel) was used to analyze the dissolution profile data for drug release kinetics. However, drug release from pellet formulation (F7) containing HPMC as a matrix former and coated with EC followed zero-order kinetics (R2 = 0.897–0.998). The release mechanism of EC-coated formulations F7, F10, and F13 was non-Fickian diffusion (anomalous transport), whereas F1 and F4 were Fickian diffusion mechanism. The stability studies of all 5% EC-coated ITP pellet formulations were conducted at room and accelerated temperature as per ICH guidelines, and results were found satisfactory. It is concluded that ethylcellulose other than Eudragit® RL/RS100 (2:1) and Kollicoat® SR 30D was found to be an excellent release controlling agent for ITP which showed good controlled-release characteristics. Note de contenu : - Materials - Methods - Physical and chemical evaluation of pellet formulations - Image analysis - In vitro drug release studies - Effect of EC coating on pellet formulations - Effect of Eudragit RL/RS 100 coating on pellet formulations - Effect of Kollicoat SR 30D coating on pellet formulations - Effect of dissolution medium on drug release - Ethylcellulose-coated pellet formulations - Eudragit RL/RS 100-coated pellet formulations - Kollicoat SR 30D-coated pellet formulations - Drug release kinetic studies - Kinetics of EC-coated pellets - Kinetics of Eudragit RL/RS100-coated pellets - Kinetics of Kollicoat SR 30D-coated pellets - Drug release mechanism - Stability studies DOI : 10.1007/s11998-019-00211-8 En ligne : https://link.springer.com/content/pdf/10.1007%2Fs11998-019-00211-8.pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=33016 [article]

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Investigation on release of highly water soluble drug from matrix-coated pellets prepared by extrusion–spheronization technique / Muhammad Iqbal Nasiri in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol. 13, N° 2 (03/2016)  

[article]  inJOURNAL OF COATINGS TECHNOLOGY AND RESEARCH > Vol. 13, N° 2 (03/2016) . - p. 333-344 Titre : Investigation on release of highly water soluble drug from matrix-coated pellets prepared by extrusion–spheronization technique Type de document : texte imprimé Auteurs : Muhammad Iqbal Nasiri, Auteur ; Rabia Ismail Yousuf, Auteur ; Muhammad Harris Shoaib, Auteur ; Muhammad Fayyaz, Auteur ; Faaiza Qazi, Auteur ; Kamran Ahmed, Auteur Année de publication : 2016 Article en page(s) : p. 333-344 Note générale : Bibliogr. Langues : Américain (ame) Catégories : Cellulose La cellulose est un glucide constitué d'une chaîne linéaire de molécules de D-Glucose (entre 200 et 14 000) et principal constituant des végétaux et en particulier de la paroi de leurs cellules. Diffusion (physique) Enrobage pharmaceutique Ethylcellulose Extrusion sphéronisation Hydroxypropyl méthylcellulose Médicaments Polymères cristallins Polymères en médecine Index. décimale : 667.9 Revêtements et enduits Résumé : The objective was to formulate itopride HCl (ITP) extended release matrix-coated pellets by extrusion–spheronization and to investigate the influence of concentration and viscosity grade of different polymers on release of a highly water soluble drug. The matrix pellet formulations consisted of polymers (10–30%) like hydroxypropyl methylcellulose (HPMC K4M, K15M, and K100M), ethyl cellulose (EC-7 cps), microcrystalline cellulose (10–30%) and a fixed quantity of lactose (10%). The initial fast drug release from the matrix pellets was effectively controlled by coating with 5% ethyl cellulose (10 cps) dispersion. The dissolution studies of coated formulations were carried out at different pH, and data were analyzed for drug release kinetics. Scanning electron microscope was used to examine the surface morphology and cross section of pellets. Kinetics of all coated formulations were best explained by Higuchi model (R 2 = 0.94–0.99). However, HPMC matrix-coated pellets (F1, F4 and F7) also followed Baker and Lonsdale model (R 2 = 0.96–0.99), whereas, EC matrix-coated pellets (F10) followed zero-order kinetics (R 2 = 0.99). Release mechanism of all coated formulations was non-fickian. Both uncoated and coated pellets were found to be spherical. Fourier transform infrared spectroscopy was conducted on the coated formulations and no drug–excipients interaction was found. Note de contenu : - Physical and chemical evaluation of uncoated ITP matrix pellet formulation - Image analysis - Scanning electron microscopy (SEM) - Fourier transform infrared spectroscopy (FTIR) - In vitro drug release studies - Drug release kinetics - Drug release mechanism - Stability studies DOI : 10.1007/s11998-015-9749-1 En ligne : https://link.springer.com/content/pdf/10.1007%2Fs11998-015-9749-1.pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26118 [article]

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