Bicosomes with β-carotene as free radical scavengers / Estibalitz Fernández in PERSONAL CARE EUROPE, Vol. 8, N° 6 (11/2015)  

[article]  inPERSONAL CARE EUROPE > Vol. 8, N° 6 (11/2015) . - p. 37-39 Titre : Bicosomes with β-carotene as free radical scavengers Type de document : texte imprimé Auteurs : Estibalitz Fernández, Auteur ; Lluís Fajarí, Auteur ; Alfonso De la Maza, Auteur ; Olga López, Auteur ; Gelen Rodríguez, Auteur ; Mercedes Cócera, Auteur ; Lucyanna Barbosa-Barros, Auteur Année de publication : 2015 Article en page(s) : p. 37-39 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antioxydants Carotène Ingrédients cosmétiques Lipides Produits antisolaires Index. décimale : 668.5 Parfums et cosmétiques Résumé : Beta-carotene antioxidant has been incorporated in a new lipid system, bicosomes, and its effectiveness against free radical formation in skin was determined using 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) spin trap and electron paramagnetic resonance spectroscopy (EPR). Dynamic light scattering (DLS) showed that the diameter of these structures is about 250 nm and cryo-transmission electron microscopy (cryo-TEM) imaged that bicosomes are formed by lipid vesicles including discoidal structures. EPR revealed that bicosomes containing β-carotene presented a high free radical scavenging activity in the skin exposed to ultraviolet radiation (UV). Note de contenu : - EXPERIMENTAL : Preparation and characterisation of the lipid systems - Dynamic light scattering (DLS) - Cryo-transmission electron microscopy (Cryo-TEM) - Preparation of skin samples - EPR measurements - RESULTS : Characterisaton of lipid system - EPR and UV radiation En ligne : https://drive.google.com/file/d/1Co5w6BphKnVrY_6ghHTgJyoKoE85To6U/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=24915 [article]

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Multi-target delivery to eliminate dark spots / Mercedes Cócera in PERSONAL CARE EUROPE, Vol. 11, N° 2 (04/2017)  

[article]  inPERSONAL CARE EUROPE > Vol. 11, N° 2 (04/2017) . - p. 137-142 Titre : Multi-target delivery to eliminate dark spots Type de document : texte imprimé Auteurs : Mercedes Cócera, Auteur ; R. Saldaña, Auteur ; Lucyanna Barbosa-Barros, Auteur ; Olga López, Auteur Année de publication : 2017 Article en page(s) : p. 137-142 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Agents de blanchiment Evaluation Peau -- Soins et hygiène Pigmentation, Troubles de la Tests d'efficacité Index. décimale : 668.5 Parfums et cosmétiques Résumé : Bicowhite complex is a sophisticated Bicosome system that works by blocking the main processes involved in the formation of dark spots. The in vitro studies demonstrated that this product is able to decrease melanin content without damaging the skin structure. This effect is explained by the interaction between the innovative Bicosome mechanism and the skin, which allows for adequate delivery and protection of the skin structure. Bicowhite has been proven effective in decreasing skin melanin content even when skin is submitted to UV radiation, which indicates that treatment with this product could a lso be carried out in sunny seasons. The in vivo studies demonstrated that Bicowhite is highly effective and specific in depigmenting dark spots, whitening, brightening, unifying skin tone and also improving the appearance of wrinkles and fine lines. The proposed multi-target delivery strategy opens up new possibilities for treatment and resolves some of the most important limitations of whitening treatments, such as lack of active penetration, disruption of skin structures, irritation, non-specificity, seasonality of treatments and, finally, insufficient efficacy. All results considered, we conclude Bicowhite is an effective and advanced whitening/brightening active ingredient to be used in all seasons. Note de contenu : - Multi-target delivery strategy - In vitro efficacy studies - Protective effect on the skin structure - Whitening activity in skin exposed to UV radiation - In vivo efficacy studies - Clinical evaluation En ligne : https://drive.google.com/file/d/1G64ydHkomIuR0kiS6hdeDHTexFyiVlYx/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28352 [article]

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