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Diverse skin benefits of an amphiphilic AsA derivative / Takeshi Nagata in GLOBAL PERSONAL CARE, Vol. 22, N° 7 (07/2021)
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Titre : Diverse skin benefits of an amphiphilic AsA derivative Type de document : texte imprimé Auteurs : Takeshi Nagata, Auteur ; Yui Oshida, Auteur ; Yoshiki Yamaguchi, Auteur ; Toshiya Tsujino, Auteur ; Shinobu Ito, Auteur Année de publication : 2021 Article en page(s) : p. 47-49 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons.
Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique...
Agents de blanchiment
Antiâge:Antirides
Antimicrobiens
Antioxydants
Ascorbique, Acide -- Dérivés
Barrière cutanée
Biomolécules actives
Peau -- Soins et hygiène
Régénération (biologie)Index. décimale : 668.5 Parfums et cosmétiques Résumé : 2-O-glyceryl-3-O-octyl ascorbate (GO-VC) is a stable amphiphilic ascorbic acid (AsA) derivative in which AsA is bound with octanol, which has antibacterial activity, and glycerin, which has a moisturising effect. GO-VC has effects that have not been confirmed with conventional AsA derivatives, such as antibacterial / antiviral effects and epidermal barrier function-reinforcing effect, and many clinical results of acne, wrinkle and pigmentation improving effects by doctors have been obtained. In recent years, an epidermal regeneration-enhancing effect has also been found, which leads to improvement of skin problems such as dryness, acne, wrinkles and pigmentation. In other words, GO-VC has a wide variety of skin physiological effects. Therefore, GO-VC could add various skin physiological effects by blending it in cosmetics and other preparations, and can be said to be an epoch-making AsA derivative. Note de contenu : - Physical characteristics
- Antioxidant effect, chlorine-removal effect, and antibacterial/antiviral effect
- Epidermal barrier function reinforcing effect
- Anti-acne effect, anti-wrinkle effect, and skin-lightening effect
- Epidermal regeneration-enhancing effect
- Fig. 1 : Chemical structure of 2-O-glyceryl-3-O-octyl ascorbate (GO-VC). INCI name Caprylyl 2-glyceryl ascorbate
- Fig. 2 : Stabilities of ascorbic acid (AsA), ascorbyl glucoside (AA2G), ascorbyl phosphate (AP, trisodium ascorbyl palmitate phosphate (APPS) and 2-O-glyceryl-3-O-octyl ascorbate (GO-VC)
- Fig. 3 : Effect of 2-O-glyceryl-3-O-octyl ascorbate (GO-VC) on the porcine epidemic diarrhea (PED) virus
- Fig. 4 : Effect of 2-O-glyceryl-3-O-octyl ascorbate (GO-VC) on the skin surface water content (SWC) and the trans-epidermal water loss (TEWL)En ligne : https://drive.google.com/file/d/1_PT4jRS4-RSnej9EXxk2aTxgx3LmotuV/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=36299
in GLOBAL PERSONAL CARE > Vol. 22, N° 7 (07/2021) . - p. 47-49[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 22813 - Périodique Bibliothèque principale Documentaires Disponible A new nonionic ascorbic acid derivative / Takeshi Nagata in PERSONAL CARE EUROPE, Vol. 7, N° 1 (02/2014)
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Titre : A new nonionic ascorbic acid derivative Type de document : texte imprimé Auteurs : Takeshi Nagata, Auteur ; Yoshiki Yamaguchi, Auteur ; Toshiya Tsujino, Auteur ; Shinobu Ito, Auteur ; Takahiro Fujimoto, Auteur ; Masato Yoshioka, Auteur Année de publication : 2014 Article en page(s) : p. 36-38 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Antibactériens
Biomolécules actives
Composés amphiphiles
Cosmétiques
Fibroblastes
Ingrédients cosmétiques
Peau -- Soins et hygiène
Tests de toxicité
Vitamine CIndex. décimale : 668.5 Parfums et cosmétiques Résumé : In cosmetic products, ascorbic acid derivatives are widely used, because of the instability of ascorbic acid (AsA) (called vitamin C as its alias). As a new nonionic and amphiphilic ascorbic-acid derivative, 2-glyceryl-3-octyl ascorbate (GO-VC), which is synthesised by introducing an octyl and a glyceryl group into ascorbic acid structure, has been recently developed. Due to its unique chemical structure, in addition to the effects of AsA, GO-VC is expected to have a humectant effect derived from glycerin and an anti-bacterial property derived from octanol, and also is highly likely to have a fibroblast activation ability, and a melanogenesis-suppressing and skin pore and wrinkle improving effect. GO-VS's safety tests, which include a human skin-sensitivity test [repeat insult patch test (RIPT)], ocular irritation test [bovine corneal opacity and permeability (BCOP) assay], genetic toxicity (Ames test), and clinical human skin patch test, have been performed, confirming the safety of GO-VC. Note de contenu : - FUNCTIONS OF GO-VC : The fibroblast proliferating ability of GO-VC - The melanogenesis-suppressing ability of GO-VC - The result of closed patch test of GO-VC - The beautifying effect of GO-VC En ligne : https://drive.google.com/file/d/1TRdaSTdHfD1FQGirbml92r5-a_XYG6BA/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=20469
in PERSONAL CARE EUROPE > Vol. 7, N° 1 (02/2014) . - p. 36-38[article]Réservation
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