Fabrication and characterization of electrospun thermoplastic polyurethane/fibroin small-diameter vascular grafts for vascular tissue engineering / E. Yu in INTERNATIONAL POLYMER PROCESSING, Vol. XXXI, N° 5 (11/2016)  

[article]  inINTERNATIONAL POLYMER PROCESSING > Vol. XXXI, N° 5 (11/2016) . - p. 638-646 Titre : Fabrication and characterization of electrospun thermoplastic polyurethane/fibroin small-diameter vascular grafts for vascular tissue engineering Type de document : texte imprimé Auteurs : E. Yu, Auteur ; J. Zhang, Auteur ; J. A. Thomson, Auteur ; Lih-Sheng Turng, Auteur Année de publication : 2016 Article en page(s) : p. 638-646 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cellules -- Cultures et milieux de culture Electrofilature Fourier, Spectroscopie infrarouge à transformée de Ingénierie tissulaire Polymères en chirurgie Polymères en médecine Polyuréthanes Protéines végétales Prothèses Prothèses vasculaires Soie et constituants Technologie médicale Textiles et tissus à usages médicaux Textiles et tissus à usages techniques Textiles et tissus à usages techniques -- Propriétés mécaniques Index. décimale : 668.4 Plastiques, vinyles Résumé : The demand for small-diameter blood vessel substitutes has been increasing due to a shortage of autograft vessels and problems with thrombosis and intimal hyperplasia with synthetic grafts. In this study, hybrid small-diameter vascular grafts made of thermoplastic polyurethane (TPU) and silk fibroin, which possessed a hybrid fibrous structure of an aligned inner layer and a random outer layer, were fabricated by the electrospinning technique using a customized striated collector that generated both aligned and random fibers simultaneously. A methanol post-treatment process induced the transition of fibroin protein conformation from the water-soluble, amorphous, and less ordered structures to the water-insoluble ?-sheet structures that possessed robust mechanical properties and relatively slow proteolytic degradation. The methanol post-treatment also created crimped fibers that mimicked the wavy structure of collagen fibers in natural blood vessels. Ultrafine nanofibers and nanowebs were found on the electrospun TPU/fibroin samples, which effectively increased the surface area for cell adhesion and migration. Cyclic circumferential tensile test results showed compatible mechanical properties for grafts made of a soft TPU/fibroin blend compared to human coronary arteries. In addition, cell culture tests with endothelial cells after 6 and 60 days of culture exhibited high cell viability and good biocompatibility of TPU/fibroin grafts, suggesting the potential of applying electrospun TPU/fibroin grafts in vascular tissue engineering. Note de contenu : - CELL CULTURE AND SEEDING - RESULTS AND DISCUSSION : Fourier transform infrared spectroscopy - Structure and morphology - Mechanical properties - Cell culture results DOI : 10.3139/217.3247 En ligne : https://drive.google.com/file/d/194seUjb8XJD2n49MLWsSuLnGz-z9Vk8L/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=27401 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
18491	-	Périodique	Bibliothèque principale	Documentaires	Disponible

Study of microcellular injection molding with expandable thermoplastic microsphere / J. Peng in INTERNATIONAL POLYMER PROCESSING, Vol. XXVI, N° 3 (07/2011)  

[article]  inINTERNATIONAL POLYMER PROCESSING > Vol. XXVI, N° 3 (07/2011) . - p. 249-255 Titre : Study of microcellular injection molding with expandable thermoplastic microsphere Type de document : texte imprimé Auteurs : J. Peng, Auteur ; E. Yu, Auteur ; X. Sun, Auteur ; Lih-Sheng Turng, Auteur ; X. F. Peng, Auteur Année de publication : 2011 Article en page(s) : p. 249-255 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Matières plastiques -- Moulage par injection d'expansion Microscopie électronique à balayage Microsphères Polyéthylène basse densité Polypropylène Polystyrène Thermoplastiques -- Moulage par injection Index. décimale : 668.4 Plastiques, vinyles Résumé : Injection molding with expandable thermoplastic microspheres (ETM) containing blowing chemicals is capable of fabricating lightweight, dimensionally stable plastic parts while using less material. This paper presents the study of microcellular injection molding of low density polyethylene (LDPE), polypropylene (PP), and polystyrene (PS) parts with various ETM contents. It was found that the molded parts exhibit relatively better surface quality than conventional foamed parts. The microcellular morphology and cell density of the fractured crosssectional surfaces were characterized using a scanning electron microscope (SEM). As reflected by the testing results, the cell microstructure – such as cell size, cell density, and a layered structure with a foamed core sandwiched by skin layers – play an important role in the weight reduction, surface quality, and mechanical properties. A smaller cell diameter and a thicker skin layer help to improve the surface quality and tensile properties of the injection molded parts with ETM. Finally, an appropriate ETM content has a positive effect on cell microstructure and weight reduction, whereas too high a concentration of microspheres adversely affects the tensile properties and surface quality. DOI : 10.3139/217.2434 En ligne : https://drive.google.com/file/d/15GGYsBMbgCOwpz-kDlc5hH3SkgDhu02q/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=12403 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
013159	-	Périodique	Bibliothèque principale	Documentaires	Disponible

---

1 (1 - 2 / 2)