Titre : |
An integrated approach to optimizing skin delivery of cosmetic and pharmaceutical actives |
Type de document : |
texte imprimé |
Auteurs : |
Steven Abbott, Auteur |
Année de publication : |
2012 |
Article en page(s) : |
p. 217-222 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Absorption cutanée Biomolécules actives Cosmétiques Extraits de plantes:Extraits (pharmacie) Formulation (Génie chimique) Perméation Solubilité
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
The academic literature on skin delivery provides countless examples of scientific insights into specific aspects of the overall process. For the practical formulator, however, it is difficult to know how to combine such insights in a way that fits into the realities of commercial formulations. In this study, five key principles are combined into an integrated approach that can be applied to real-world formulations. Given the complexities of skin science, the integrated approach cannot be expected to be highly precise. Instead, it is intended as a way for a formulation team to balance the many conflicting issues. The predictions are sufficiently specific to be examined by those with the appropriate analytical resources and data on formulation efficacy. It is hoped that such challenges will allow the approach to be refined for the future. |
Note de contenu : |
- Ideal solubility
- Solubility and partition
- Diffusion
- Multiple ingredients
- Finite dose
- The integrated approach
- The basics
- The fate of the formulation on the skin |
DOI : |
10.1111/j.1468-2494.2012.00710.x |
En ligne : |
http://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2012.00710.x |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=15030 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 34, N° 3 (06/2012) . - p. 217-222