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Noninvasive in situ assessment of structural alteration of human dermis caused by photoaging using a novel collagen-specific imaging technique / Toyonobu Yamashita in IFSCC MAGAZINE, Vol. 16, N° 1 (01-02-03/2013)

[article]  inIFSCC MAGAZINE > Vol. 16, N° 1 (01-02-03/2013) . - p. 3-7 Titre : Noninvasive in situ assessment of structural alteration of human dermis caused by photoaging using a novel collagen-specific imaging technique Type de document : document électronique Auteurs : Toyonobu Yamashita, Auteur ; Yuki Ogura, Auteur ; Yuji Tanaka, Auteur ; Ryosuke Tanaka, Auteur ; Takeshi Yasui, Auteur ; Tsutomu Araki, Auteur ; Tetsuji Hirao, Auteur Année de publication : 2013 Article en page(s) : p. 3-7 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Collagène Génération de seconde harmonique La génération de seconde harmonique (GSH) également appelé doublage de fréquence) est un processus d'optique non-linéaire dans lequel des photons interagissant avec un matériau non-linéaire sont combinés pour former de nouveaux photons avec le double de l'énergie, donc avec le double de la fréquence ou la moitié de la longueur d'onde des photons initiaux. Imagerie médicale Microscopie Photovieillissement (dermatologie) Index. décimale : 668.5 Parfums et cosmétiques Résumé : Specific visualization and assessment of human collagen fibers were demonstrated using a developed second-harmonic-generation (SHG) microscope equipped with a Cr:forsterite laser (1250 nm). Initially, we examined the specific sensitivity of SHG imaging for collagen fibers using excised human skin specimens. Age-related dermal alterations in female subjects were then evaluated by means of SHG microscopy. The developed SHG microscope enabled us to observe the collagen fibers in the skin sections ; their SHG images correlated well with the Elastica-van-Gieson-stained sections of dermal fibers. In vivo imaging of human skin with a wide field of view as also achieved. En face SHG images of facial skin of female subjects of different ages showed the structural alterations in the collagen fiber network. Additional image analysis of SHG images based on two-dimensional Fourier transformation also reflected age-related alterations. In conclusion, this proposed methodology can be a powerful tool in fields such as anti-aging dermatology and validation of the efficacy of cosmetic products. Note de contenu : - MATERIALS AND METHODS : Optical imaging systems - Specific sensitivity to collagen fibers - Evaluation of human skin - RESULTS AND DISCUSSION : Comparison of SHG images and elastica-van-Gieson stained section images - In vivo visualization of human cheek skin - Age-related alteration of collagen fibers Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=17826 [article]

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Validation of a web-based imaging system for 'at-home' facial skin analysis / Greg. G. Hillebrand in IFSCC MAGAZINE, Vol. 16, N° 1 (01-02-03/2013)

[article]  inIFSCC MAGAZINE > Vol. 16, N° 1 (01-02-03/2013) . - p. 9-14 Titre : Validation of a web-based imaging system for 'at-home' facial skin analysis Type de document : texte imprimé Auteurs : Greg. G. Hillebrand, Auteur ; Bill Halas, Auteur ; Pat Lafleur, Auteur ; Frances Maddin, Auteur ; Mani Thomas, Auteur ; Richard Thomas, Auteur Année de publication : 2013 Article en page(s) : p. 9-14 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Dermatologie Imagerie (technique) Peau -- Rides Pigmentation, Troubles de la Taches pigmentaires (dermatologie) Télédermatologie Vieillissement cutané Index. décimale : 668.5 Parfums et cosmétiques Résumé : Facial imaging and quantitative image analysis of facial skin features, especially of those features associated with aging and beauty such as wrinkles and dark spots, are essential and routine in cosmetic science and aesthetic dermatology. However, these methods and services are reserved primarily for the research lab, clinic, spa or department store counter. Toward the goal of bringing this technology into the home, we have developed a web-based imaging system whereby facial images, captured using ordinary digital cameras and with modest attention to lighting, resolution and zoom, can be uploaded to a central server and analyzed for the severity of facial wrinkles and dark spots. Photographic standardization, essential for reproducible and quantitative image analysis, is aided by a universal headband worn during image capture. Functioning as an internal reference standard, color ships and other graphic information on the headband are employed by server-based software to verify image quality and make corrections for variation in lighting, resolution, and registration prior to image analysis. In this paper, we compare the web-based system's precision, accuracy, and linearity to a benchmark facial imaging system (VISIA). We also assess the system's utility for tracking changes in facial skin hyperpigmentation before and after dermatologic treatment. Note de contenu : - EXPERIMENTAL : Repeatibility - Accuracy and linearity - Differentiation and user acceptance - Image database - RESULTS AND DISCUSSION : Headband design - Image specifications and capture - Image upload - Image analysis - WBIS repeatibility - WBIS accuracy and linearity - WBIS differentiation Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=17827 [article]

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Impact of cleansing products on the skin surface pH / Uwe Aßmus in IFSCC MAGAZINE, Vol. 16, N° 1 (01-02-03/2013)

[article]  inIFSCC MAGAZINE > Vol. 16, N° 1 (01-02-03/2013) . - p. 17-24 Titre : Impact of cleansing products on the skin surface pH Type de document : texte imprimé Auteurs : Uwe Aßmus, Auteur ; Bernhard Banowski, Auteur ; Michael Brock, Auteur ; Jessica Erasmy, Auteur ; Andreas Fitzner, Auteur ; Uta Kortemeier, Auteur ; Silke Langer, Auteur ; Sven Munke, Auteur ; Hartmut Schmidt-Lewerkühne, Auteur ; Doerte Segger, Auteur ; Gunja Springmann, Auteur ; Claudia Wood, Auteur ; Jürgen Blaak, Auteur Année de publication : 2013 Article en page(s) : p. 17-24 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques Peau -- Nettoyage Peau -- Soins et hygiène pH -- Mesure Savon Index. décimale : 668.5 Parfums et cosmétiques Résumé : The project was conducted to evaluate the effect on the skin surface pH of application of surfactant systems of different pH. Enhancement of the physiological stratum corneum pH leads to abnormal epidermal barrier function. Skin cleansing products are known to influence the skin surface pH. Studies have shown that various effects on the skin surface pH are related to a pH shift and restoration. Because of the varying results, a literature survey and a multicenter study were performed to evaluate the effect of skin cleansing on skin surface pH. The literature survey was conducted on the topic "Influence of cleansing products on skin pH". Moreover, a controlled and randomized multicenter study was performed with 63 healthy male and female subjects. The skin surface pH was measured before and after a standardized washing procedure with three different cleansing products and water. Publications since 1970 reveal different methods, conditions, panels and effects on skin surface pH. The changes in skin surface pH described after skin cleansing vary ±0 to +3.0 units. Biophysical measurements show that not only the product pH but also the combination of surfactants is a crucial factor in maintaining the natural skin pH. Finding the optimal ratio of surfactants in combination with an acidic product pH between 4 and 5 will be an important challenge for cosmetic chemists in the future. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=17828 [article]

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Tetrapeptide to minimize facial redness and the induced negative effects of an exaggerated inflammatory response / Marta Rull in IFSCC MAGAZINE, Vol. 16, N° 1 (01-02-03/2013)

[article]  inIFSCC MAGAZINE > Vol. 16, N° 1 (01-02-03/2013) . - p. 27-34 Titre : Tetrapeptide to minimize facial redness and the induced negative effects of an exaggerated inflammatory response Type de document : texte imprimé Auteurs : Marta Rull, Auteur ; Cristina Davi, Auteur ; Elena Cañadas, Auteur ; Wim Van Den Nest, Auteur ; Raquel Delgado, Auteur Année de publication : 2013 Article en page(s) : p. 27-34 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques Interleukines Les interleukines (IL) sont un groupe de cytokines, ainsi nommées car les premières observations semblaient montrer qu'elles étaient exprimées par les globules blancs (leucocytes, d'où -leukin) en guise de moyen de communication (d'où inter-). Les interleukines sont produites par une large variété de tissus et cellules, et que, bien que regroupées sous cette terminologie par commodité, elles ne présentent aucune parenté biochimique ni de fonction entre elles. Elles ont été classées par numéro au gré des découvertes. Au début 2006, 31 cytokines sont connues et dénommées sous l'intitulé IL. La fonction du système immunitaire dépend en grande partie des interleukines et de rares déficiences de certaines d'entre elles ont été décrites, conduisant à des maladies auto-immunes ou des immunodéficiences. Peau -- Inflammation Peau -- Soins et hygiène Peptides Index. décimale : 668.5 Parfums et cosmétiques Résumé : Inflammatory overreactions are linked to skin redness, dilated capillaries, skin flushing, hyperpigmentation and other disturbing skin manifestations that affect millions of individuals. Although its etiology is uncertain, the natural response of the immune system to damaging agents has a clearly relevant role, with kallikreins and antimicrobial compounds (like cathelicidins) being key elements. Active cathelicidins trigger a cascade of reactions that lead to a rise in pro-inflammatory cytokines and interleukins, which results in inflammation also alters skin firmness and elasticity by degrading extracellular matrix compounds. In skin with redness, the active cathelicidin LL-37 and the interleukins interleukin-6 and IL-8 present at abnormally high levels, so their diminution should consequently help to decrease the undesired visible effects. Acetyl tetrapeptide-40 not only reduced the LL-37-induced interleukin-6 and IL-8 levels, collagen degradation, melanogenesis and tyrosinase activity (linked to hyperpigmentation) i nvitro but strongly reduced facial redness, erythema and its extent in volunteers with mild rosacea after just one week. After four weeks, it provided excellent results, with visible facial improvements. Additionally, this peptide provided a noticeable photoprotective in vitro effect. Thus, this peptide is an excellent option to reduce skin redness and its associated consequences. Note de contenu : - EXPERIMENTAL : Inhibition of the release of LL-37-induced interleukins - Anti-collagenase assay - Anti-tyrosinase assay - Melanogenesis inhibition on human epidermal melanocytes - Photoprotection test on human dermal fibroblasts - Dermatological evaluation - RESULTS AND DISCUSSION : Inhibition of the release of LL-37-induced interleukins - Anti-collagenase assay - Anti-tyrosinase assay - Melanogenesis inhibition in human epidermal melanocytes - Photoprotection test in human dermal fibroblasts - Dermatological evaluation - Digital analysis of skin redness with the visia TM system Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=17829 [article]

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