[article]
| Titre : |
What is the most suitable strategy for stress proteins in cosmetics? |
| Type de document : |
texte imprimé |
| Auteurs : |
Christine Jeanmaire, Auteur ; Vincent Bardey, Auteur ; Louis Danoux, Auteur ; Philippe Moser, Auteur ; Philippe Moussou, Auteur ; Gilles Pauly, Auteur |
| Année de publication : |
2003 |
| Article en page(s) : |
p. 221-226 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Tags : |
Cytoprotection 'Heat shock proteins' Pollution Skin 'Skin defense' Stress UV |
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Under various stress conditions, heat shock protein expression is enhanced in cells. Working on skin pieces, two of the major skin-expressed heat shock proteins, HSP72 and HSP27, were visualized by immunohistochemistry after several stress conditions (UV, pollutants, thermal shocks) and the heat shock protein expression quantified in the epidermis. A strong increase of the epidermal heat shock protein expression, due to these different stresses, was observed. The most suitable cosmetic strategy is discussed: does one need to prevent or to favor heat shock protein induction in cutaneous cells?
A prevention strategy is suitable in the case of acute stress, such as severe UV exposure that provokes cell damage and a strong induction of heat shock proteins. It is demonstrated that, using a photoprotective active ingredient Sunactyl®, suppression of the heat shock protein expression of cells is linked to a protection of the cells against UV induced damages.
An induction strategy is appropriate for chronic daily stress from various sources. Seeing that a small and controlled induction of heat shock proteins in the skin speeds up the response and enhances the cellular resistance to further stress, HSP-Balance® was developed, which boosts the heat shock protein induction in the skin under stress conditions. |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10584 |
in IFSCC MAGAZINE > Vol. 6, N° 3 (07-08-09/2003) . - p. 221-226
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What is the most suitable strategy for stress proteins in cosmetics? in IFSCC MAGAZINE, Vol. 6, N° 3 (07-08-09/2003)
