Elucidation of the anti-aging effects of ectoine using cdna microarray analysis and signaling pathway evaluation / Soheila Anzali in IFSCC MAGAZINE, Vol. 12, N° 4 (10-11-12/2009)

[article]  inIFSCC MAGAZINE > Vol. 12, N° 4 (10-11-12/2009) . - p. 381-385 Titre : Elucidation of the anti-aging effects of ectoine using cdna microarray analysis and signaling pathway evaluation Type de document : texte imprimé Auteurs : Soheila Anzali, Auteur ; Anja von Heydebreck, Auteur ; Thomas Herget, Auteur Année de publication : 2010 Article en page(s) : p. 381-385 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge Cosmétiques Ectoine Index. décimale : 668.5 Parfums et cosmétiques Résumé : A human three-dimensional skin model was treated with ectoine in two different concentrations for four days. Gene expression profiling was performed using cDNA microarray analysis. A network analysis of the deregulated genes yields hypotheses regarding potential molecular mechanisms leading to anti-aging effects of ectoine. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10142 [article]

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Extremolytes : fighting urban stress by the model of nature / Eva Galik in PERSONAL CARE EUROPE, Vol. 12, N° 2 (04/2018)  

[article]  inPERSONAL CARE EUROPE > Vol. 12, N° 2 (04/2018) . - p. 169-172 Titre : Extremolytes : fighting urban stress by the model of nature Type de document : texte imprimé Auteurs : Eva Galik, Auteur ; Janina Kienemund, Auteur Année de publication : 2018 Article en page(s) : p. 169-172 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Actifs anti-pollution Cosmétiques Ectoine Peau -- Effets de la lumière Peau -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : Due to its global skin protection and regenerating efficacy, the extremolyte ectoine became a well-established active ingredient in the part years. Its unique and global anti-pollution activity has been demonstrated in vivo by analysis of barrier lipid oxidisation levels from the skin surface as well as in human lungs, where ectoine reduces inflammations induced by pollution particles. Ectoine's visible light protection property results in the reduction of the cell's oxidative stress response to visible light irradiation and the prevention of hyperpigmentation. In addition, the natural amino acid derivate regenerates environmentally irritated skin including the skin barrier function due to its strong anti-inflammatory benefits. In conclusion, ectoine is a multifunctional and safe active ingredient with clinically proven efficacy - very well-suited for cosmetic formulations, which need to match various consumer demands and market trends. Note de contenu : - Mode of action - Skin barrier repair - Anti-pollution efficacy of ectoine - Visible light and its influence on skin - Ectoine : visible light protection - FIGURES : 1. Ectoine hydro complex - 2. Protection shell around protein formed by ectoin hydro complexes - 3. Average values of TEWL improvement - 4. In vivo study design : smoke applicationon skin with standardised chamber system - 5. Nrf2 immunostaining of the negative control, placebo and 1% ectoine pre-treatment batch with an dwithout visible light irradiation - 6. MC1R immunostaining of the negative control, placebo and 1% ectoine pre-treatment batch with and without visible light irradiation En ligne : https://drive.google.com/file/d/163-6IYHWMsulGGjbHJq3VzuVkDIeOGHq/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30472 [article]

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Natural ectoin : Protecting against air pollution / Janina Kienemund in GLOBAL PERSONAL CARE, Vol. 23, N° 5 (05/2022)  

[article]  inGLOBAL PERSONAL CARE > Vol. 23, N° 5 (05/2022) . - p. 29-32 Titre : Natural ectoin : Protecting against air pollution Type de document : texte imprimé Auteurs : Janina Kienemund, Auteur Année de publication : 2022 Article en page(s) : p. 29-32 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Actifs anti-pollution Biomolécules actives Dermo-cosmétologie Ectoine Peau -- Effets de la pollution atmosphérique Peau -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : Air pollution is not only a major threat to global climate, but also to our health. According to the World Health Organization (WHO), 99 % of the world’s population breathes air with excessive pollutant concentrations. Defined by the WHO as 'contamination of the indoor or outdoor environment by any chemical, physical or biological agent that modifies the natural characteristics of the atmosphere', air pollution negatively affects every organ of the body, including the skin, so there is a great need for products that provide protection against pollutants. In cosmetic applications, the market for active ingredients reducing skin damage induced by air pollution has been growing continually for the last seven years. bitop’s natural Ectoin is a well-known multifunctional active whose anti-pollution and protection efficacy was proven in clinical, placebo-controlled in vivo and ex vivo studies. Furthermore, natural Ectoin has been suggested by independent experts for the use as an anti-pollution active and was also approved for medical treatment and prevention of lung diseases such as pollution-induced chronic obstructive pulmonary disease (COPD) and asthma. Chronic exposure to environmental conditions such as UV, blue light and air pollution has been shown to have a significant impact on skin health and aging. It is an indisputable fact that cutaneous aging is mainly driven by external stress factors, promoting the formation of reactive oxygen species (ROS), encouraging inflammation processes in tissues and cells, and compromising the natural skin barrier. This results in an increase of transepidermal water loss, along with a decrease in skin thickness, skin elasticity and the occurrence of wrinkles and pigment spots. In addition, dermatoses like rash, eczema, allergies, psoriasis, and atopic dermatitis are caused or reinforced by external influences. Protecting the skin from external stress factors and the prevention of cell damage are therefore logical and effective strategies for decelerating premature skin aging and treating disease-affected skin. Note de contenu : - Pollution and its impact on skin - Studies demonstrate negative impact of air pollution - Skincare rides to the rescue - Natural Ectoin : a bioactive with comprehensive protection efficacy En ligne : https://drive.google.com/file/d/1qx9zFeW1C0J83P1EYfmQkBQNjJmcDGZK/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37729 [article]

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Natural molecule offering anti-pollution benefits / Janina Kienemund in GLOBAL PERSONAL CARE, Vol. 23, N° 10 (11/2022)  

[article]  inGLOBAL PERSONAL CARE > Vol. 23, N° 10 (11/2022) . - p. 25-28 Titre : Natural molecule offering anti-pollution benefits Type de document : texte imprimé Auteurs : Janina Kienemund, Auteur ; Eva Galik, Auteur ; René Schmitz, Auteur Année de publication : 2022 Article en page(s) : p. 25-28 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Actifs anti-pollution Agents de blanchiment Barrière cutanée Dermo-cosmétologie Ectoine Ingrédients cosmétiques Lumière bleue Peau -- Soins et hygiène Protection cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : German active ingredient supplier bitop explains why the natural extremolyte Ectoin is suited for cosmetic formulations for all skin types, matching various consumer demands and market trends such as anti-pollution, blue light protection and whitening. Human skin is situated at the interface of the organism and its environment and is therefore constantly exposed to numerous extrinsic stress factors. Chronic exposure to environmental conditions, including ultraviolet light (UV), blue light and air pollution has been shown to have a significant impact to skin health and ageing. It is an indisputable fact that cutaneous ageing is mainly driven by external stress factors, promoting the formation of reactive oxygen species (ROS), encouraging inflammation processes in tissues and cells and compromising the natural skin barrier. This results in an increase of trans-epidermal water loss (TEWL), along with a decrease of skin thickness, skin elasticity and the occurrence of wrinkles and pigment spots. Additionally, dermatoses like rash, eczema, allergies, psoriasis and atopic dermatitis are caused or exacerbated by external influences. Protecting the skin from external stress-factors and the prevention of cell damage thus are logical and effective strategies to slow down premature skin ageing and treat disease affected skin. In recent years, stress-protection molecules, so-called extremolytes, have become popular as cosmetic active ingredients, e.g. bitop Ectoin® natural (hereafter referred to by its INCI name, Ectoin). Note de contenu : - Skin barrier repair - Pigmentation against pollution induced pigmentation - Protection against blue light induced pigmentation - Whitening and lightening efficacy - Table 1 : Depigmenting effect and skin lightening - Table 2 : Reduction of different pigmentation En ligne : https://drive.google.com/file/d/1t9suX9WYTGg1n9kpnxZutDXRqXDGdd2f/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38702 [article]

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