A study of anti-wrinkle functions and improvement of cream with Phaseolus angularis / Sarang Oh in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 46, N° 2 (04/2024)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 46, N° 2 (04/2024) . - p. 318-332 Titre : A study of anti-wrinkle functions and improvement of cream with Phaseolus angularis Type de document : texte imprimé Auteurs : Sarang Oh, Auteur ; Jeehaeng Jeong, Auteur ; Myeongju Kim, Auteur ; Xiangji Jin, Auteur ; Shengdao Zheng, Auteur ; Yong-Min Kim, Auteur ; Tae-Hoo Yi, Auteur Année de publication : 2024 Article en page(s) : p. 318-332 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge:Antirides Biomolécules Biomolécules actives Cosmétiques Dermo-cosmétologie Extraits de plantes:Extraits (pharmacie) Matériaux -- Propriétés fonctionnelles Phaseolus angularis - Qu'est-ce que Phaseolus angularis ? : Les haricots Adzuki ou Aduki sont des légumineuses de couleur rouge, originaires du sud-est de l'Asie, principalement du Japon et de la Chine. En tant que légumineuses, elles sont riches en hydrates de carbone et en protéines. - Utilisation et avantages : Les haricots Adzuki séchés sont broyés, puis utilisés comme pâte à appliquer sur le visage, ce qui donne une action exfoliante douce à la peau. Il est utilisé comme ingrédient dans les masques pour le visage et le corps, le beurre corporel et les gommages nettoyants. (Lesielle) Index. décimale : 668.5 Parfums et cosmétiques Résumé : Chronic exposure to ultraviolet (UV) radiation from sunlight accelerates skin ageing, which is followed by harsh, thick, dry and loose conditions. One of the most demonstrative symptoms is deep wrinkles induced by skin barrier disruption. Our previous research showed that Phaseolus angularis seed extract (PASE) effectively inhibits skin ageing through UVB protection in HaCaT cells by suppressing skin damage. However, its efficacy has not been evaluated in clinical trials so far. PASE cream's effectiveness was initially tested on the artificial skin model, revealing an increase in filaggrin and defence against skin damage. Based on these results, in this single-centred, randomized, double-blind study, we investigated the anti-ageing effect of PASE in human eye wrinkle areas. For these 21 healthy adult women aged 30 to 59, a PASE cream was applied to the right eye wrinkle area and a placebo to the left eye wrinkle area twice a day (morning and evening) for 12 weeks. The change in thick, deep crease wrinkles around the eyes was confirmed by visual evaluation, skin measurements and a questionnaire. As a result, the surface roughness (R1), maximum roughness (R2), average roughness (R3), smoothness depth (R4) and arithmetic mean roughness (R5) values in the group using the PASE cream all decreased. Particularly, R1, R4 and R5 significantly decreased by 18.1%, 18.6% and 25.0%, respectively. Subjects who applied PASE cream also experienced an improvement in skin moisture nearly twice the time compared to the placebo group. In addition, no participants reported side effects. Our study showed that PASE cream led to clinically significant levels of wrinkle improvement. In conclusion, as PASE is a natural, safe food with no side effects, it can be a good resource for natural anti-wrinkle functional cosmetics in the future. Note de contenu : - MATERIALS AND METHODS : Preparation of Phaseolus angularis seed extract cream - High-performance liquid chromatography (HPLC) analysis - Immunohistochemistry staining with artificial skin model - Subjects and study design - Treatment - Manufacturing of the replica - Visual assessment - Photography - Non-invasive skin measurements - Moisturization assessment - Questionnaire study - Skin safety assessment - Statistical analysis - RESULTS : Analysis of chemical contents of PASE cream - H&E and fillagrin staining - Visual evaluation and photography - Skin measurement and analysis - Moisturization assessment after treatment - Self-satisfaction assessment after treatment - Safety results DOI : https://doi.org/10.1111/ics.12932 En ligne : https://drive.google.com/file/d/1z5E9rSPW16H0IEtVoaRGgUhChL6r46Mh/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40915 [article]

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