Collagenases and their inhibitors : a review / Sijin Wu in COLLAGEN AND LEATHER, Vol. 5 (2023)  

[article]  inCOLLAGEN AND LEATHER > Vol. 5 (2023) . - 20 p. Titre : Collagenases and their inhibitors : a review Type de document : texte imprimé Auteurs : Sijin Wu, Auteur ; Xuewei Zhou, Auteur ; Zhicheng Jin, Auteur ; Haiming Cheng, Auteur Année de publication : 2023 Article en page(s) : 20 p. Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antienzymes Collagénases Les collagénases sont des enzymes capables de rompre les liaisons peptidiques du collagène. Elles facilitent la destruction des structures extracellulaires lors de la pathogenèse bactérienne. Ce sont des exotoxines. La production de collagénases peut être induite lors d'une réponse immunitaire, par les cytokines qui stimulent les cellules telles que les fibroblastes et les ostéoplastes et occasionnent indirectement des lésions tissulaires. Cuirs et peaux Enzymes microbiennes Epilage enzymatique Métalloprotéinases Index. décimale : 675 Technologie du cuir et de la fourrure Résumé : Hide and skin are complex tissue where the most abundant component is collagen. Matrix metalloproteinases and bacterial collagenases are two kinds of collagenases that can cleave the triple-helical domain of native fibrillar collagens. In this paper, the family members and domain composition of matrix metalloproteinases and bacterial collagenases are summarized. The catalytic mechanism of collagen hydrolysis by collagenases is described, and the methods adopted to date for investigating and regulating collagenases and their inhibitors are reviewed. Furthermore, the applications of collagenases and their inhibitors in biomedicine, food processing and the enzymatic unhairing process in the leather-making industry are presented. Note de contenu : - PROGRESS OF RESEARCH ON COLLAGENASES : research on collagenases - MMPs - Bacterial collagenases - Applications of collagenases - REGULATORY APPROACHES USING COLLAGENASE INHIBITORS : Zinc-binding inhibitors - Non zinc-binding inhibitors - Applications of collagenase inhibitors - Table 1 : Classification of MMP family with their domain organization and substrates preference - Table 2 : Applications of collagenases in the biomedical field - Table 3 : List of inhibitors with different inhibitory principles - Table 4 : List of MMP-13 inhibitors for the treatment of OA - Table 5 : List of bacterial collagenases (ColH) inhibitors DOI : https://doi.org/10.1186/s42825-023-00126-6 En ligne : https://link.springer.com/content/pdf/10.1186/s42825-023-00126-6.pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40069 [article]

Exemplaires

Code-barres	Cote	Support	Localisation	Section	Disponibilité
aucun exemplaire

Decoding source of leather odor : a quantitative analysis with heracles NEO / Haonan Shi in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA), Vol. CXIX, N° 4 (04/2024)  

[article]  inJOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA) > Vol. CXIX, N° 4 (04/2024) . - p. 165-173 Titre : Decoding source of leather odor : a quantitative analysis with heracles NEO Type de document : texte imprimé Auteurs : Haonan Shi, Auteur ; Haiming Cheng, Auteur ; Jin Zhou, Auteur Année de publication : 2024 Article en page(s) : p. 165-173 Note générale : Bibliogr. Langues : Américain (ame) Catégories : Analyse quantitative (chimie) Composés organiques volatils -- Analyse Cuir Cuirs et peaux de bovins Cuirs et peaux de moutons Odeurs -- Analyse Olfactométrie Index. décimale : 675 Technologie du cuir et de la fourrure Résumé : Leather products are widely used in our daily life and in close contact with users, but the pleasant feeling during its usage is severely affected by the odor volatilized from the leather surface. In this study, a quantitative analysis method to investigate the differences in the odor profiles among four types of leather was proposed. The primary olfactory constituents of four leather types were examined by Heracles NEO ultra-fast gas-phase electronic nose, including Principal Component Analysis (PCA) and Discriminant Factor Analysis (DFA). In chrome-tanned cattle hide leather, the substance with the highest content was 2,4-Dinitrotoluene, while methyl dodecanoate was the predominant compound in chromefree cattle hide leather. Notably, chrome-tanned sheepskin leather exhibited higher levels of dodecanal, clopyralid, n-octylbenzene, propyl cinnamate, and 3-methylhexadecane. Similarly, chrome-free sheepskin leather contained higher levels of dodecanal, clopyralid, n-octylbenzene, propyl cinnamate, 3-methylhexadecane, and tetradecanol. These findings indicate that each of the four types of leather possesses distinctive compounds, while also sharing common compounds. Furthermore, the results indicate that radar plots along with PCA and DFA analyses can effectively differentiate between the four types of leather. Note de contenu : - EXPERIMENTAL : Materials and sampling process - Heracles NEO instrumentation and settings - Data analysis and comparison - RESULTS : Qualitative analysis of volatile compounds by Heracles NEO e-nose - Chemical pattern recognition analysis - PCA principal component analysis - DFA discriminant factor analysis - Table 1 : The set parameters of Heracles NEO - Table 2 : Possible volatile compounds identified in CTCL and relative contents - Table 3 : Possible volatile compounds identified in CFCL and relative contents - Table 4 : Possible volatile compounds identified in CTSL and relative contents - Table 5 : Possible volatile compounds identified in CFSL and relative contents DOI : https://doi.org/10.34314/yv80gx56 En ligne : https://drive.google.com/file/d/1zb1DL6sd8C_ks6W60OR52x0MHQ4lDigX/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40824 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
24674	-	Périodique	Bibliothèque principale	Documentaires	Disponible

---

1 (1 - 2 / 2)