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Challenges and effective routes for formulating and delivery of epidermal growth factors in skin care / Olivia Eskens in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 2 (04/2021)
[article]
Titre : Challenges and effective routes for formulating and delivery of epidermal growth factors in skin care Type de document : document électronique Auteurs : Olivia Eskens, Auteur ; Samiul Amin, Auteur Année de publication : 2021 Article en page(s) : p. 123-130 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Cosmétiques
Emulsions -- Emploi en cosmétologie
Facteur de croissance (biochimie)
Formulation (Génie chimique)
Peau -- Soins et hygiène
Systèmes de livraison (pharmacie)Index. décimale : 668.5 Parfums et cosmétiques Résumé : Epidermal growth factors are important morphogenetic proteins that instruct cell behaviour. They have many inferred applications within regenerative medicine and have shown promising results in skincare treatments. Many growth factors are known to have skin anti-ageing benefits along with further potential in resolving scarring, acne and other skin disorders. Incorporation of these biologics into skincare formulations has been greatly hindered by low transdermal delivery efficacy, intricate material interactions and protein instability – especially within common cosmetic emulsions. This review explores the cosmeceutical capability of growth factors in skin care, current understandings of constituent interactions and advantageous delivery approaches for more effective topical delivery. The first section highlights the influences growth factor product formulation has on stability and synergy. Current understandings of growth factor formulating techniques in cosmetic products is limited, and the performance of other protein structures is an adequate point of reference. The second section examines emerging drug delivery systems to overcome the challenges of topical growth factor treatment. It is important to consider the coaction and durability of all components in a formulation simultaneously : active ingredients, product format and delivery vehicle, in order to engineer an optimal cosmeceutical product. Note de contenu : - FORMULATION OF EPIDERMAL GROWTH FACTORS IN SKIN CARE : Stability of EGF in formulations - Stability of EGF in manufacturing - Stability of EGF in storage - Bioengineering - Synergistic EGF formulation
- TOPICAL DELIVERY TECHNIQUES FOR EPIDERMAL GROWTH FACTORS : Physical enhancers - Scaffolds - Particulate systems - Liposomes - Smart response
- Table 1 : EGF wound-healing patent formulations
- Table 2 : Stability criteria for EGF product development
- Table 3 : Summary of topical delivery systemsDOI : https://doi.org/10.1111/ics.12685 En ligne : https://drive.google.com/file/d/1nR28nQTZ5sTpP84T27UXkx_flesvh9F8/view?usp=shari [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35752
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 2 (04/2021) . - p. 123-130[article]