| Titre : |
Taking a regenerative approach to hair growth |
| Type de document : |
texte imprimé |
| Auteurs : |
Masakazu Hashimoto, Auteur ; Ryo Nishiyama, Auteur ; Arunasiri Iddamalgoda, Auteur ; Ichimaru Pharcos, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 55-58 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cheveux -- Croissance
Cheveux -- Soins et hygiène
Etudes cliniques
Extraits de plantes:Extraits (pharmacie)
Follicule pileux
Ingrédients cosmétiques
Produits capillaires
Régénération (biologie)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Hair loss is an issue that relates to both men and women of all ages. Recent studies for hair growth are being conducted on dermal papilla and there have been several pathways that have been identified such as the Wnt signalling pathway.
RSPO1 is one of the recent novel proteins required for organ development, and is secreted from dermal papilla cells in the hair follicle. It has two functions - a promoter role and a protector role in the hair cycle. Nasturtium officinale Leaf/Stem Extract, a novel hair growth ingredient increases RSPO1 secretion from the derma papilla, and binds to the outer root sheath to promote hair follicle growth, and also neutralises the hair loss factor Dickkopf-related protein 1 (DKK1) to protect hair growth. The result of in vitro, ex vivo, and human clinical trial confirmed the efficacy of the special processed Nasturtium officinaleLeaf/Stem Extract (commercially known as ‘Burgeon-Up’) to effectively promote hair growth through RSPO1 enhancement. |
| Note de contenu : |
- Focusing on RSPO1
- Enhancing RSPO1
- Suppression of DKK1 secretion
- Hair follicle elongation ex vivo
- Human clinical trial
- Fig. 1 : RSPOA action site in human hair
- Fig. 2 : RSPO1 enhancing Wnt activity
- Fig. 3 : Nasturtium officinale Leaf/Stem Extract promoting RSPO1 secretion
- Fig. 4 : Nasturtium officinale Leaf/Stem Extract promoting DKK1 secretion
- Fig. 5 : Elongation of human hair follicle (ex vivo) by Nasturtium officinale Leaf/Stem Extract
- Fig. 6 : Hair parameters of the clinical study volunteers
- Fig. 7 : Phototrichogram analysis of an active group volunteer at 0 month and 3 months
- Fig. 8 : Visual change of hair volume from a 51 year old volunteer from 0 month, 3 months and 6 months |
| En ligne : |
https://drive.google.com/file/d/1TLk_VI8x2MFgIgib_wR9NXqI_0SPOQBx/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34280 |
in PERSONAL CARE EUROPE > Vol. 14, N° 3 (06/2020) . - p. 55-58
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