| Titre : |
New melanobreaker strategy for skin whitening |
| Type de document : |
texte imprimé |
| Auteurs : |
Eve Bosseboeuf, Auteur ; Gabrielle Moro, Auteur ; Pierre-Yves Morvan, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 43-46 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Agents de blanchiment
Chromophycophytes
Dermo-cosmétologie
Extraits de plantes:Extraits (pharmacie)
Ingrédients cosmétiques
Peau -- Soins et hygiène
Pigmentation de la peau
Taches pigmentaires (dermatologie)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Science and new technology have made molecular data accessible and it is thanks to this informational context that we are able to identify the main players involved in the skin pigmentation process.
Genes that use signalling pathways are this study's ideal targets for assessing the efficacy of the main active agents to be developed. In the laboratory, a new brown algae extract has been revealed to us with potential implications for regulating the expression of genes participating in melanogenesis. The results have indeed come to show that the extract is able to inhibit the expression of those genes responsible for melanin synthesis activation, as well as to activate the genes responsible for their degradation. In addition to possessing uncommon properties by virtue of the alga’s iridescence, this extract, called CyWhite, helps to naturally rebalance skin pigmentation. |
| Note de contenu : |
- Melanogenesis : how does skin get its colour ?
- Genes involved in skin pigmentation regulation : ideal targets
- In vivo efficacy : overall assessment of homogeneity and lightening effect
- Fig. 1 : The rainbow algae in its natural environment and its hand harvesting
- Fig. 2 : Regulatory genes involved in pigment synthesis pathways in the keratinocytes and melanocytes
- Fig. 3 : Expression of POMC and CSTE in reconstituted epidermis models treated or not with CyWhite
- Fig. 4 : Expression of AGRP, DKKA and CTSL2 in reconstituted epidermis model treated or not with CyWhite
- Fig. 5 : Effect of CyWhite on ITA° of pigmentation spots of the face after 8 weeks of application compared to the placebo
- Fig. 6 : Effect of CyWhite on the colour difference ΔE between a pigmentation spot and the "normal" skin of the face
- Fig. 7 : Extract from responses by volunteers to the self-assessment questionnaire |
| En ligne : |
https://drive.google.com/file/d/1X9VZNUNaCJanOJPJelsJq4zB54oRWEri/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34278 |
in PERSONAL CARE EUROPE > Vol. 14, N° 3 (06/2020) . - p. 43-46
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