Titre : |
Rice mesistem cultures rejuvenate skin |
Type de document : |
texte imprimé |
Auteurs : |
Philip Ludwig, Auteur ; Suellen Bennett, Auteur ; James V. Gruber, Auteur |
Année de publication : |
2011 |
Article en page(s) : |
p. 67-72 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Antiâge Cellules méristématiques Dermo-cosmétologie Peau -- Soins et hygiène Riz et constituants
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Growing red rice meristem cultures in bioreactors is a sustainable process that reduces residual biomass waste, but the benefits of this technology are not limited to environmental impact. Through elicitation of red rice meristematic cell cultures, we were able to produce appreciable quantities of secondary metabolites in the culture. When the culture was tested on fibroblasts in vitro, we showed a reverse in the age-related increase of methylation in the promoter region of genes. This rejuvenation at the epigenetic level may have multiple benefits to the cells and to the skin. Some benefits include anti-ageing and the renewal of gene and protein expression levels to that found in younger cells. In essence, the skin, through an application of ReGeniStem Red Rice, is pushed to a younger, healthier state. An increased expression of dermatopontin in keratinocytes, besides being a novel finding, implies that ReGeniStem Red Rice may be able to firm the skin and improve the skin barrier function. |
Note de contenu : |
- Plant tissue culture
- Secondary metabolites induced by ozone stress
- Product identification
- Overview of DNA methylation as a type of epigenetic modification : DNA CpG methylation - Global and gene promoter DNA methylation - Epigenetic changes and ageing
- DNA methylation summary and experimentation introduction
- In vitro efficacy studies : Global decrease of CpG methylation in gene promoter regions - CpG methylation at collagen 1A1 (COL1A1) gene - in vitro pro-collagen 1 synthesis - Dermatopontin expression in keratinocytes |
En ligne : |
https://drive.google.com/file/d/1e-P3GKYfBEGRCMLlo0nD6KTlla4KczAZ/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40978 |
in PERSONAL CARE EUROPE > Vol. 4, N° 4 (11/2011) . - p. 67-72