| Titre : |
Innovative approach to control acne-prone skin |
| Type de document : |
texte imprimé |
| Auteurs : |
M.L. Và zquez-Gonzà lez, Auteur ; M. Cócerra, Auteur ; J. Nestor, Auteur ; G. RodrÃguez, Auteur ; R. Saldaña, Auteur ; Lucyanna Barbosa-Barros, Auteur ; O. López, Auteur |
| Année de publication : |
2018 |
| Article en page(s) : |
p. 153-156 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons.
Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique...
Cosmétiques
Dermo-cosmétologie
Etude in vivo
Evaluation
Evaluation visuelle
Peau -- Soins et hygiène
Statistiques
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Excessive sebum production can give rise to oily skin, shiny appearance, enlarged pores and favour the development of acne lesions. The care of acne-prone skin involves the use of harsh molecules, wash out and multi-step products that irritate the skin and limit user compliance. This study describes the development of a bicosome system that targets the epidermis and follicles to effectively deliver a sebostatic active compound and potentiate its effects on sebum production and acne lesion prevention. This is an alternative approach to that offered by current products, which can be included in the daily care of acne-prone skin. |
| Note de contenu : |
- METHODOLOGY : Skin penetration studies - In vivo studies - Instrumental evaluation - Clinical evaluation - Statistical studies
- RESULTS AND DISCUSSIONS : Skin penetration studies - In vivo studies: assessment of sebum excretion - Prevention of acne lesions - Clinical evaluation: prevention of new acne lesions - Visual evaluation of the volunteers by the dermatologist - Tolerance study
- FIGURES : 1. Cryo-TEM (Transmission Electron Microscopy) image of a Bicosome showing internal disc structures and the surrounding vesicle. Bar ) 200nm - 2. Microscope images from skin samples treated with a control solution of niacimide labelled with fluorescein and skin samples treated with the bicomide system labelled with fluorescein - 3. Average sebum amount ± SE at different experimental days (0,15 and 30) during the treatment with bicomide - 4. Visiopor photographs of the skin under UV light from different volunteers before and after the treatment with bicomide - 5. Decreases of the average % area covered by porphyrins ± SE at different experimental times during the treatment with bicomide - 6. Reduction of acne lesions after 30 days using bicomide - 7. Evaluation of the level of acne evaluated by the dermatologist (n=20) - 8. Visioface macrophotographs of volunteers showing the evolution of relevant acne lesions before and after the use of bicomide |
| En ligne : |
https://drive.google.com/file/d/1LeQIgcjUyNV75AmoiPo2UdLbbDCOwDAz/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30468 |
in PERSONAL CARE EUROPE > Vol. 12, N° 2 (04/2018) . - p. 153-156
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