Titre : |
Bitter is better : new way to sooth sensitive skin |
Type de document : |
texte imprimé |
Auteurs : |
Bernd Walzel, Auteur ; Anja Herrmann, Auteur ; Ulrike Bätz, Auteur ; Beatrix Senti, Auteur ; Tamina Shah, Auteur ; Stefan Bänziger, Auteur |
Année de publication : |
2023 |
Article en page(s) : |
p. 61-64 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Biomolécules actives Dermo-cosmétologie Ingrédients cosmétiques Peau -- Soins et hygiène Récepteurs du goût Sensibilité cutanée
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Good medicine tastes bitter, said Confucius. Indeed, many active pharmaceutical ingredients taste bitter, manifesting the cross-cultural believe that the bitterness of medicine is correlated with beneficial pharmacological activity. Bitter taste receptors have recently been discovered in skin. Their activation triggers the synthesis of skin barrier lipids, making them novel targets for the treatment of sensitive skin. Amaretine® (hereafter called the bittersweet complex) builds on this new knowledge by combining bitter with sweet components : bitter andrographolide from Andrographis paniculata leaves and sweet glycyrrhetinic acid from Glycyrrhiza glabra roots activate the skin’s bitter receptors and reduce inflammatory responses. Both active components are enclosed in a liposomal carrier system for optimal dermal delivery, to synergistically comfort sensitive skin. The bittersweet complex performs excellently in consumer surveys, where people with sensitive skin report a reduction in redness, itching, stinging, or burning sensations after treatment. This action was further confirmed in clinical studies, as well as in placebo controlled in vivo and in vitro studies. Finally, we could show that improving symptoms of sensitive skin measurably improves the quality of life of affected people. |
Note de contenu : |
- Characteristics of sensitive skin
- Bitter taste receptors in skin - novel cosmetic targets
- Andrographis paniculata - an activator of bitter taste receptors in skin
- Sweet tasting licorice root - a source of natural anti-inflammatory compounds
- The novel approach : first system of bitter and sweet for sensitive skin
- The bittersweet complex restores bitter taste receptor levels in atopic skin
- Bittersweet complex reverses an imbalanced gene expression in atopic skin
- Bittersweet complex regenerates the skin barrier and protects from irritation
- The bittersweet complex eases symptoms of sensitive skin & improves the quality of life |
En ligne : |
https://drive.google.com/file/d/1uXjmaaL3lGPQ1Yv0D7UWff5n2G_TjUe8/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39412 |
in GLOBAL PERSONAL CARE > Vol. 24, N° 4 (04/2023) . - p. 61-64