| Titre : |
A novel ester-bonded gemini quaternary ammonium salt with good antimicrobial activity and anti-mold performance for wet blue leather |
| Type de document : |
texte imprimé |
| Auteurs : |
Tao Zhang, Auteur ; Chunhua Wang, Auteur ; Jun Sang, Auteur ; Long Zhang, Auteur ; Yuanhang Xiao, Auteur ; Wei Lin, Auteur |
| Année de publication : |
2022 |
| Article en page(s) : |
p. 131-140 |
| Note générale : |
Bibliogr. |
| Langues : |
Américain (ame) |
| Catégories : |
Ammoniums quaternaires
Antifongiques
Antimicrobiens
Esters
Evaluation
Toxicologie cellulaire
Wet-blue (tannage)Peau tannée au chrome (le chrome donne une couleur bleue)
|
| Index. décimale : |
675.2 Préparation du cuir naturel. Tannage |
| Résumé : |
Herein, we have developed a kind of novel ester-bonded gemini quaternary ammonium salts microbicides named QAS(n+m) for leather application, in which n and m denotes the number of −CH2 between the ester groups on the spacer, and the length of alkyl chain connected to ester groups on the hydrophobic tail chain, respectively. Results indicate that the hydrophobic tail lengths and the spacer lengths in the QAS(n+m) structures affect their antimicrobial activities very differently. QAS(4+10) was used to investigate the antimicrobial mechanism, cytotoxicity, and antimold performance for wet blue leather as it exhibits the strongest antimicrobial effect. It shows QAS(4+10) is capable of inactivating microorganisms mainly by disrupting the integrity of their cell membranes. Compared to commercial leather microbicide product 2-thiocyanomethylthiobenzothiazole (TCMTB), QAS(4+10) exhibits comparable mold resistance and lower toxicity. The present work gives positive insight into the development of novel candidate microbicides for the preservation of wet blue leather. |
| Note de contenu : |
- MATERIALS AND METHODS : Syntheses of gemini quaternary ammonium salts QAS(n+m) - Antimicrobial activity evaluation
- ANTIMICROBIAL MECHANISM STUDY : Scanning electron microscopy (SEM) observation - Determination of K+ and soluble proteins content - Live/dead bacteria staining assay - Cytotoxicity assay ( CCK-8 test) - Anti-mold performance of QAS(4+10) for wet blue leather
- RESULTS AND DISCUSSION : Antimicrobial activity evaluation - Antimicrobial mechanism study - Citotoxicity evaluation - Anti-mold performance of QAS(4+10) for wet blue leather
- Table 1 : The MIC, MBC and MFC values of QAS(n+m) against different microorganisms
- Table 2 : The K+ content and the soluble proteins content in the supernatant of A. niger spores with different treatment |
| DOI : |
https://doi.org/10.34314/jalca.v117i4 |
| En ligne : |
https://drive.google.com/file/d/1tpOpnHyYmlv6rkLycYRZXVVVJYwuJ4Cz/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37560 |
in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA) > Vol. CXVII, N° 4 (04/2022) . - p. 131-140
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A novel ester-bonded gemini quaternary ammonium salt with good antimicrobial activity and anti-mold performance for wet blue leather in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA), Vol. CXVII, N° 4 (04/2022)
