| Titre : |
Preparation and evaluation of a UV-curing hydrophilic semi-IPN coating for medical guidewires |
| Type de document : |
texte imprimé |
| Auteurs : |
Wenfei Ding, Auteur ; Zheng Zhao, Auteur ; Lingmei Jiang, Auteur ; Xigao Jian, Auteur ; Yuan Song, Auteur ; Jinyan Wang, Auteur |
| Année de publication : |
2021 |
| Article en page(s) : |
p. 1027–1035 |
| Note générale : |
Bibliogr. |
| Langues : |
Américain (ame) |
| Catégories : |
Adhésion
Biocompatibilité
Caractérisation
Copolymère uréthane acrylate
Copolymères -- Synthèse
Durée de vie (Ingénierie)
Enrobage (technologie)
Essais (technologie)
Hydrophilie
Morphologie (matériaux)
Mouillabilité
Mouillage (chimie des surfaces)
Oligomères
Photoréticulation
Polyéthylene glycol diacrylate
Polyvinylpyrrolidone
Réseaux polymères
Revêtements -- Séchage sous rayonnement ultraviolet
Revêtements organiques
|
| Index. décimale : |
667.9 Revêtements et enduits |
| Résumé : |
Guidewires have crucial roles in intravascular, critical care, and urological applications. In recent years, the demand for guidewires with lower friction surfaces has arisen for medical applications. Among various surface lubrication strategies for guidewires, the most promising is the use of a hydrophilic coating. However, obtaining a hydrophilic coating on guidewires with strong adhesion remains difficult owing to the surface energy difference between the substrate and hydrophilic coating. Herein, we present a UV-curing semi-interpenetrating polymer network coating for medical thermoplastic polyurethane (TPU)-sheathed nitinol guidewires. A polyurethane acrylate (PUA) was synthesized and cured as a transition layer on the TPU substrate to provide strong adhesion. Then, polyvinyl pyrrolidone (PVP) and polyethylene glycol diacrylate (PEGDA) permeated into the PUA layer and cured to form the composite coating. The PUA–PEGDA–PVP coating exhibited excellent lubricity and satisfactory adhesion force. The surface coefficient of friction decreased to approximately 0.02 after modification with the coating, and the coating was stable during long-term soaking in water and repeated friction. In vitro toxicity tests revealed that the coating had good biocompatibility. Thus, our PUA–PEGDA–PVP coating has the potential for application as super-lubricity guidewires and other medical devices. |
| Note de contenu : |
- EXPERIMENTAL MATERIALS AND METHODS : Materials - Synthesis of PUA oligomer - Preparation of prepolymer solution - Preparation of PUA–PEGDA–PVP coating on TPU panels and guidewires - Characterization - Cross-cut tests - Wetting tests - Friction tests - Durability tests -In vitro cytotoxicity testsHemolytic test
- RESULTS AND DISCUSSION : Synthesis of the PUA oligomer - Preparation and morphology of the PUA–PEGDA–PVP coating - Adhesion and wetting ability - Lubricating performance of PUA–PEGDA–PVP - guidewires - Durability of the PUA–PEGDA–PVP coating - In vitro toxicity and hemolysis |
| DOI : |
https://doi.org/10.1007/s11998-021-00455-9 |
| En ligne : |
https://link.springer.com/content/pdf/10.1007/s11998-020-00455-9.pdf |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=36210 |
in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH > Vol. 18, N° 4 (07/2021) . - p. 1027–1035
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Preparation and evaluation of a UV-curing hydrophilic semi-IPN coating for medical guidewires in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol. 18, N° 4 (07/2021)
