| Titre : |
Sebum regulation, the ethical way ! |
| Type de document : |
texte imprimé |
| Auteurs : |
Romain Reynaud, Auteur ; Yohan Rolland, Auteur ; Bénédicte Sennelier-Portet, Auteur ; Amandine Scandolera, Auteur ; Mélanie Pélican, Auteur ; Morgane de Tollenaere, Auteur ; Emilie Chapuis, Auteur |
| Année de publication : |
2021 |
| Article en page(s) : |
p. 16-21 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antibactériens
Biomolécules actives
Dermo-cosmétologie
Etudes cliniques
Ingrédients cosmétiques
Manguier et constituants
Peau -- Soins et hygiène
Séborrhée
Sébum
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Derived from the green fractionation of mango leaves, Mangixyl™ (also referred as 'Mangifera Indica leaves active') is an effective cosmetic ingredient that is microbiome-friendly with proven efficacy targeting oil skin through sebum regulation. The cosmetic innovation activates specific receptors of gene’s pathway normally regulated by the highly potent retinoic acid.
In an era where sustainability and traceability are top of mind for consumers, the sourcing story of Mangixylâ„¢ highlights our commitment to our Company Purpose. The mango leaves are collected in collaboration with the Association Bendia, based in Koro village (Burkina Faso, Africa). The association is a women-led initiative to contribute to the improvement of the living conditions of the community. Thus, Mangifera Indica leaves active is an ingredient good for the consumers, good for the planet and good for the people.This ingredient aims to relieve consumers from the discomfort caused by oily skin. It activates some receptors of the retinoic acid-regulated genes pathway and decreases in vitro, ex vivo and in vivo the synthesis of lipids on all skin ethnicities. Additional clinical data showed efficacy against prone-to-acne skin, and on the regulation of sebum on scalp hair. Amidst the current COVID-19 crisis, it also provides an effective response to the "maskne" phenomenon which has been gaining momentum lately. |
| Note de contenu : |
- Sourced responsibly
- Botanical expertise in phytochemistry
- Mangifera indica active and its anti-bacterial effect
- Stretegy to reduce sebum overexpression
- Regulation of same transcription factors than retinoids : Indentification of the inhibition pathway by RT-qPCR : (Inverse) molecular docking determination
- Biological activities of the ingredient : Reduction of sebum production (in vitro) - Lipogenesis inhibition ve retinoic acid on 3 ethnicities (in vitro) - Reduction of the volume of sebaceous glands (ex vivo)
- Clinical efficacy : sebum reduction on 3 skin complexion (in vivo)
- Clinical efficacy : Improvement of the quality of the skin (in vivo)
- A microbiome-friendly active ingredient |
| En ligne : |
https://drive.google.com/file/d/1TBGARRKZKlPZ4ZqSaYvQVJUgwJehQHsy/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35888 |
in SOFW JOURNAL > Vol. 147, N° 5 (05/2021) . - p. 16-21
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Sebum regulation, the ethical way ! in SOFW JOURNAL, Vol. 147, N° 5 (05/2021)
