[article]
| Titre : |
Eriodictyon angustifolium extract, but not Eriodictyon californicum extract, reduces human hair greying |
| Type de document : |
document électronique |
| Auteurs : |
N. Taguchi, Auteur ; T. Hata, Auteur ; E. Kamiya, Auteur ; T. Homma, Auteur ; A. Kobayashi, Auteur ; H. Aoki, Auteur ; T. Kunisada, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 336-345 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cellules -- Cultures et milieux de culture
Cheveux -- Soins et hygiène
Cheveux décolorés
Extraits de plantes:Extraits (pharmacie)
Mélanogénèse
Produits capillaires
Statistique
StérubineLa stérubine (S-7-méthoxy-3',4',5-trihydroxyflavanone) est une flavanone (C16H14O6) qui a la capacité de masquer l'amertume de composé amer.
Cette flavanone a été identifiée dans un extrait des feuilles de l'Herba Santa (Eriodictyon californicum)2, une plante poussant dans le nord du Mexique et dans l'État de Californie3.
Dans cette même plante, trois autres flavonoïdes ont été identifiés avec la même capacité à modifier le goût : l'ériodictyol, l'homoériodictyol et son sel de sodium (homoériodictyol sodique)2.
La flavanone est extraite par un solvant non miscible avec l'eau, ensuite les corps gras sont éliminés. L'extrait est éventuellement préépuré sur charbon actif, puis traité avec une solution à base de sodium ionique. Pour finir, le sel de sodium d'homoériodictyol est précipité et purifié par reprécipitation ou cristallisation à température inférieure à 40 °C. (Wikipedia)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
- Objective : Yerba Santa (Eriodictyon angustifolium and Eriodictyon californicum) has been used for many years in traditional medicine. However, the effect of Yerba Santa on melanogenesis has not yet been investigated. We aimed to assess the biological effects of Yerba Santa on hair pigmentation.
- Methods : Yerba Santa extracts were assessed for their cytological effects following X-ray irradiation treatment and then tested directly for the prevention of human hair greying. Ultra-performance liquid chromatography (UPLC) was utilized to identify the individual extract components.
- Results : Eriodictyon angustifolium extract significantly increased melanin synthesis in the melanoma cell line through activation of the WNT/MITF/tyrosinase-signalling pathway. In contrast, E. californicum had no effect on melanin synthesis. E. angustifolium extract also demonstrated a protective effect against the damage induced by X-ray irradiation in human keratinocytes. Application of the extracts to subjects who had grey beards demonstrated a reduced number of grey beard hair per year specifically with the E. angustifolium extract. A significant decrease in grey head hair was also observed after application of E. angustifolium extract. Upregulation of gene expression related to melanin production and WNT signalling was observed after the application of E. angustifolium extract. Sterubin was the most abundant flavonoid detected by UPLC in E. angustifolium extract. In addition, sterubin showed the highest difference in terms of quantity, between E. angustifolium and E. californicum extract.
- Conclusion : Eriodictyon angustifolium extract, which is abundant in sterubin, may be suitable as a potential cosmetic and medical agent for the prevention and improvement of hair greying. |
| Note de contenu : |
- MATERIALS AND METHODS : Materials - Preparation of the plant extracts - Cell culsture - Measurement of cellular melanin - Immunohistochemistry - Measurement of cH2AX activation in normal human epidermal keratinocytes after irradiation - Measurement of reactive oxygen species (ROS) - Assessment of mitochondrial mass - Clinical testing - Gene expression analysis - Ultra-performance liquid chromatography (UPLC) of Yerba Santa extract - LabCyte MELANO-MODEL - Statistical analysis
- RESULTS : Ea but not Ec extract increases melanin synthesis and WNT, MITF and TYR expression in a human melanoma cell line - Ea extract shows a suppressive effect on radiation-induced DNA damage and cell death in normal human epithelial keratinocytes - Effect of Ea extract for the prevention and improvement of human beard hair greying - Effect of Ea extract on the prevention and improvement of human head hair greying - Gene expression analysis after Ea and Ec extract application to human skin - The flavonoid compound sterubin is the active component of Ea extract for protection against hair greying |
| DOI : |
https://doi.org/10.1111/ics.12620 |
| En ligne : |
https://drive.google.com/file/d/1lDv84Hi8NfsBnbDLNKlJe4ZEbUhOogAs/view?usp=shari [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35285 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 42, N° 4 (08/2020) . - p. 336-345
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Eriodictyon angustifolium extract, but not Eriodictyon californicum extract, reduces human hair greying in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 42, N° 4 (08/2020)
