| Titre : |
Next generation dandruff control |
| Type de document : |
texte imprimé |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 8-13 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antimicrobiens
Antipelliculaires
Biomolécules actives
Caprylate de propanediol
Cosmétiques
Cuir chevelu -- Soins et hygiène
Dermo-cosmétologie
Emulsions -- Emploi en cosmétologie
Produits capillaires
shampooings
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Dandruff is a global phenomenon and the need for cosmetic products to relieve symptoms like flaking, itching and redness remains high [1]. Anti-dandruff consumer products in the cosmetics market typically rely on the use of strong anti-fungal ingredients. Three conventional actives are commonly used from a global perspective : zinc pyrithione, climbazole and piroctone-olamine.
Except for a limited selection of multifunctionals, some blends or natural extracts, there has been no major new active launched to market for decades. In this article we present an entirely new solution : propanediol caprylate (Crinipan® PMC green), a novel molecule for cosmetic applications, developed to serve multiple needs: comparable efficacy to conventional anti-dandruff actives, natural origin, green chemistry, sustainability, new mode of action and simple formulating.
|
| Note de contenu : |
- MATERIALS AND METHODS : Production process – Antimicrobial efficacy against malassezia – Determination of microbial ester cleavage – In vivo study assessing reduction of dandruff – Physicochemistry : Effect on foam and sensorial properties
- RESULTS : In vitro efficacy – In vivo efficacy – Physicochemistry : Effect on foam and sensorial properties
- Fig. 1 : Suggested mechanism for propanediol caprylate’s mode of action ; presence of malassezia spp « activates » propanediol caprylate to release the active caprylic acid
- Fig. 2 : The IC values for propanediol caprylate are in a similar range as for caprylic acid. The efficacy of caprylic acid can be used for cosmetic purpose by applying its ester
- Fig. 3 : Rinse off shampoo study : propanediol caprylate reduces dandruff significantly in a 30 days studyvs placebo and achieves comparable results to the established anti-dandruff benchmark climbazole
- Fig. 4 : Physicochemical behavior : Propanediol caprylate improves foam and sensorial experience of skin
- Table 1 : Malassezia test strains
- Table 2 : In vivo shampoo study ; test shampoos
- Table 3 : In vivo shampoo study ; conditioning phase ; mild wash-out shampoo from the market
|
| En ligne : |
https://drive.google.com/file/d/1XABUolaFKuZuk77h_1NEB10nLy23emq0/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35001 |
in SOFW JOURNAL > Vol. 146, N° 12 (12/2020) . - p. 8-13
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Next generation dandruff control in SOFW JOURNAL, Vol. 146, N° 12 (12/2020)
