Titre : |
Nature's know-how and plant cell technology to combat infrared- and ultraviolette-induced photoaging |
Type de document : |
texte imprimé |
Auteurs : |
Hagen Döring, Auteur ; Emilio Rubio, Auteur ; Miguel Perez-Aso, Auteur ; Blanca Martinez-Teipel, Auteur ; Jordi Bosch, Auteur ; Ricard Armengol, Auteur |
Année de publication : |
2016 |
Article en page(s) : |
p. 2-8 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Anti-inflammatoires Antiâge:Antirides Antioxydants Biomolécules actives Cosmétiques Dermo-cosmétologie Extraits de plantes:Extraits (pharmacie) Peau -- Soins et hygiène Vieillissement cutané -- Prévention
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
The term Photoaging describes the ageing process of our skin that is caused by ultraviolet (UV) and infrared (IR) solar radiation. UV - and IR - induced damage to our skin includes, but is not limited to, DNA alterations, an increased level of cellular oxidative stress and inflammatory reaction in our skin. All of these processes lead to premature ageing and poor biomechanical characteristics.
Our laboratory has developed the active ingredient Lingostem, which is based on a polyphenolrich lingonberry (Vaccinium vitis-idaea) cell line. The anti-oxidative capacity was 11 times higher than that of the natural berries. Lingostem counteracts the negative effects of IR and UV radiation by potentiating the antioxidant response, decreasing the inflammatory reaction and reducing MMP-1 production.
Two independent in vivo studies showed the protective and restorative capacity of Lingostem. Especially impressive were the improvement of the sub-epidermal echogenic band and a significant wrinkle reduction relative to placebo. |
Note de contenu : |
- PLANT CELL TECHNOLOGY
- METHODS : DPPH Free Radical Scavenging activity - Cell Culture and Irradiation Conditions - Quantitative RT-PCR after UV-B Irradiation - Evaluation of p38 phosphorylation after IR-A Irradiation - Evaluation of Hydrogen Peroxide Production after IR-A Irradiation - Quantitative RT-PCR: MMP-1 after IR-A Irradiation - In vivo Photoaging Studies
- RESULTS : DPPH Free Radical Scavenging Activity - Anti-inflammatory Effect after UV-B: Quantitative RT-PCR - Effect on p38 Activation Induced by IR-A - Cellular Oxidative Stress: Evaluation of Hydrogen Peroxide after IR-A Irradiation - Effect on Gene Expression after IR-A Irradiation: MMP-1 - In vivo Photoaging Studies |
En ligne : |
https://drive.google.com/file/d/1mmwV2v9Rv8QgRNfIXQoI1tfq43a1Pdjf/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=27851 |
in SOFW JOURNAL > Vol. 142, N° 11 (11/2016) . - p. 2-8