| Titre : |
The effects of Areca catechu L extract on anti-inflammation and anti-melanogenesis |
| Type de document : |
texte imprimé |
| Auteurs : |
Kun-Kook Lee, Auteur ; Jung-Do Choi, Auteur |
| Année de publication : |
1999 |
| Article en page(s) : |
p. 275–284 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Tags : |
'Piégeage des radicaux libres' Hyaluronidase Tyrosinase 'Anti-mélanogénèse' Antioxydants 'Palmier à bétel' |
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Ethanolic extract (CC-516) from Areca catechu L was prepared and its various biological activities were evaluated, CC-516 showed potent anti-oxidative, free radical scavenging, and anti-hyaluronidase activity. Anti-oxidative effect of CC-516 (IC : 45.4 μg/ml) was lower than butylated hydroxytoluene (IC : 5μg ml), but similar to tocopherol and higher than ascorbic acid. Especially, CC-516 exhibited relatively high free radical scavenging activity (IC : 10.2 μg/ml) compared to control. CC-516 inhibited effectively hyaluronidase activity (IC: : 416 μg/ml), showed inhibition in vivo on delayed hypersensitivity as well as croton-oil induced ear edema in mice when it was topically applied. These results strongly suggest that CC-516 may reduce immunoregulatory/inflammatory skin trouble. Also, from the results, we have elucidated that CC-516 showed anti-allergic and anti-cytotoxicity activity. The whitening effect of CC-516 shown by the inhibition of mushroom tyrosinase activity with IC of 0.48 mg/ml and of melanin synthesis in B16 melanoma cells. This study indicates that CC-516 is effective on anti-inflammatory/anti-melanogenesis, and can be used as a new agent for cosmetics. |
| DOI : |
10.1046/j.1467-2494.1999.196590.x |
| En ligne : |
https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.196590.x |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26485 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 4 (08/1999) . - p. 275–284
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The effects of Areca catechu L extract on anti-inflammation and anti-melanogenesis in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 21, N° 4 (08/1999)
