| Titre : |
A novel ingredient with 3R effect targeting impure skin |
| Type de document : |
texte imprimé |
| Année de publication : |
2016 |
| Article en page(s) : |
p. 18-27 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons.
Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique...
Anti-inflammatoires
Dermatite sébhorrhéique
Formulation (Génie chimique)
Ingrédients cosmétiques
Peau -- Soins et hygiène
Séborrhée
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
RonaCare® SereneShield (INCI:Butyl Hydroxycyclohexane Carboxylate) is an adequate new solution to an issue well-known from our teenage years and yet rarely associated with adulthood : oily skin and its consequences on the appearance of acne formation. The success of this ingredient is linked to its 3R effect : RonaCare® SereneShield Regulates sebum, Reduces inflammation and Rebalances skin microflora. In order to substantiate the sebum regulation claim, in vitro testings showing the reduction of the enzyme 5-a reductase type but also in vivo ones with determination of skin surface sebum reduction were performed. The reduction of inflammation was supported by colony counting tests showing the growth reduction of P. acnes but also by 3D biofilm model showing the inhibition of P. acnes biofilm. In vivo investigation showed the decrease of the inflammatory metabolites porphyrins. Finally, to support the skin microflora rebalance claim, in vitro colony counting tests were done showing the specificaction of RonaCare SereneShield on non-beneficial bacteria, while marginally affecting beneficial ones. Reduction of non-beneficial bacteria adhesion could be verified on human reconstructed epidermis. Overall, a novel ingredient has been found with a unique mode of refining consumer's skin complexion towards a healthier and more aesthetic look. |
| Note de contenu : |
- REGULATION OF SEBUM : Reduction of 5-α reductase Type I - Reduction of in vivo skin surface sebum
- REGULATION OF INFLAMMATION : P. acnes growth reduction - Inhibition of biofilm (Determination of SMIC - Biofilm inhibition via dynamic fluid exchange 3D biofilm model) - In vivo investigations (Visualization of bacterial porphyrins - Redness and inflammation)
- REGULATION OF SKIN MICROFLORA : In vitro colony counting assay on P. acnes and S. epidermidis - Reduction of adhesion of S. aureus on reconstructed human epidermis (RHE)
- FORMULATIONS |
| En ligne : |
https://drive.google.com/file/d/1QwRAKDhC1dOdfBYMeWhpdNaVAv81o5z3/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26316 |
in SOFW JOURNAL > Vol. 142, N° 5 (05/2016) . - p. 18-27
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A novel ingredient with 3R effect targeting impure skin in SOFW JOURNAL, Vol. 142, N° 5 (05/2016)
