Age-dependent changes in eumelanin composition in hairs of various ethnic origins / S. Commo in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 34, N° 1 (02/2012)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 34, N° 1 (02/2012) . - p. 102-107 Titre : Age-dependent changes in eumelanin composition in hairs of various ethnic origins Type de document : texte imprimé Auteurs : S. Commo, Auteur ; K. Wakamatsu, Auteur ; Isabelle Lozano, Auteur ; S. Panhard, Auteur ; G. Loussouarn, Auteur ; B. A. Bernard, Auteur ; S. Ito, Auteur Année de publication : 2012 Article en page(s) : p. 102-107 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cheveux Dopachrome Tautomerase Eumélanine Mélanine Tags : Âge  'Dopachrome  tautomerase'  'Origine  ethnique'  Eumélanine  'Mélanine  cheveu' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Hair pigmentation is one of the most conspicuous phenotypes of humans. From a chemical point of view, however, data remain scarce regarding human hair pigmentation characteristics. To determine melanin content and composition in human eumelanic hair from individuals of different ethnic origins and at different ages, we collected hair from 56 subjects with eumelanic hair from each group of African-American, East Asian, and Caucasian origin. The 56 subjects consist of 14, seven each of males and females, each from four age classes of younger than 11, between 12 and 19, between 20 and 45, and older than 46. We analysed hair colour scale, total melanin value, and contents of pyrrole-2,3,5-tricarboxylic acid (PTCA) and pyrrole-2,3-dicarboxylic acid (PDCA). We measured age-dependent increases in the relative quantity of eumelanin in pigmented human hairs in the three ethnic groups. Regarding melanin composition, we observed an increase in the PDCA/PTCA ratio with age in African-American and Caucasian hairs until approaching the quite constant level of the ratio in East Asian hairs in the elderly individuals. Our results evidence differences in the content and composition of eumelanin in human hair among African-American, Caucasian and East Asian individuals. Furthermore, we show evidence of age-dependent changes in the quantity and quality of eumelanin in pigmented human hairs. In particular, the age-dependent modification of the PDCA/PTCA ratio, a marker for 5,6-dihydroxyindole units in eumelanin, suggests a chronological evolution of hair follicle melanocyte phenotype (e.g. decrease in dopachrome tautomerase expression). Note de contenu : - MATERIALS AND METHODS : Hair samples - Chemical analyses - Statistical analyses - RESULTS : Pigmentation scores in the three ethnic groups - Effect of age on quantity and quality of eumalenin DOI : 10.1111/j.1468-2494.2011.00691.x En ligne : http://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2011.00691.x Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=13285 [article]

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