| Titre : |
Tackling under-eye dark circles with a responsibly sourced root extract |
| Type de document : |
texte imprimé |
| Année de publication : |
2023 |
| Article en page(s) : |
p. 10-15 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Biomolécules actives
Contour des yeux -- Soins et hygiène
Extraits de plantes:Extraits (pharmacie)
Ingrédients cosmétiques
Peau -- Soins et hygiène
Racines végétales
Vascularisation (dermatologie)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
This paper aims to demonstrate that using an eco-responsible technology called Plant Milking it is possible to produce a new active ingredient from the roots of Ipomoea batatas. Rich in dicaffeoyl quinate esters (DCQEs), this extract efficiently tackles several pathways leading to under eye dark circles to improve the eye contour aspect. A full transcriptomic study was done and demonstrated that genes involved in the main biological pathways leading to dark circles formation were downregulated. This study was completed by an evaluation of the effects of the active on vascularization using an innovative 3D vascularized dermis model, showing the active ingredient helps modulate the formation of new vessels. An ex-vivo assessment demonstrated it can re-densify the dermis. To confirm the benefits for consumers a clinical evaluation showed eye contour color was improved in only 7 days and eye stiffness was increased thanks to this Ipomoea batatas root extract. |
| Note de contenu : |
- Using plant milking technology to responsibly source new active ingredients
- Root-extracted active that takcles under eye dark circles and puffiness
- Proven to act on 5 causes of dark circles : Regulation of genes involved in dark circles etiology - Vascular network control - Dermis densification
- Clinical tests show a strong improvement in under aspect |
| En ligne : |
https://drive.google.com/file/d/1z15BsSV6FvPcL_5xES2wSp_SmSyRcx3Z/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40381 |
in SOFW JOURNAL > Vol. 149, N° 11 (11/2023) . - p. 10-15
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