| Titre : |
Mild retinol alternative for global compliance |
| Type de document : |
texte imprimé |
| Auteurs : |
Marcie Natale, Auteur ; Stéphanie Clendennen, Auteur |
| Année de publication : |
2023 |
| Article en page(s) : |
p. 31-34 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge:Antirides
Dermo-cosmétologie
Etudes cliniques
Formulation (Génie chimique)
Linoléate de rétinyle
Peau -- Soins et hygiène
Rétinoïdes
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Retinoids are the gold standard for reducing signs of agins when applied topicallly to the skin. Familiar examples of retinoids are retinoic acid, retinol, and retinol esters like retinyl palmitate. Retinol is highly effective, but it can be unstable in formulation and irritating to skin at cosmetically useful levels.
In one review of published studies, retinol was associated with skin redness, dryness and flaking. Derivatizing retinol can reduce its potential for irritation and improve its stability. In particular, fatty acid derivatives of retinol can deliver high efficacy without the irritation.
Retinyl linoleate is a compound composed of retinol and high-purity linoleic acid from safflower oil joined by an ester bond. Retinyl biloleate is a biobased, formulation-stable, easy-to-handle, nonirritating antiaging ingredient. Retinhl linoleate is historically known to be non-irritating and stable in formulation.
|
| Note de contenu : |
- EXPERIMENTAL METHODS : Materials - Formulations for in vitro studies - In vitro gene expression - In vitro permeation and hydrolysis in a skin model - Clinical study - Expression of retinoid marker genes - Retinol binding proteins - Retinoic acid binding proteins - Permeation and hydrolysis of retinyl esters in a skin model - Clinical trial results fonfirm the efficacy of retinyl linoleate |
| En ligne : |
https://drive.google.com/file/d/1CsdXQfGin-JCWR-4TLda_dXm_oo1ADhf/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39406 |
in GLOBAL PERSONAL CARE > Vol. 24, N° 4 (04/2023) . - p. 31-34
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