Mussel-inspired principle for prosthesis coatings / Wolfdietrich Meyer in ADHESION - ADHESIVES + SEALANTS, Vol. 21, N° 3/2024 (2024)  

[article]  inADHESION - ADHESIVES + SEALANTS > Vol. 21, N° 3/2024 (2024) . - p. 30-32 Titre : Mussel-inspired principle for prosthesis coatings Type de document : texte imprimé Auteurs : Wolfdietrich Meyer, Auteur Année de publication : 2024 Article en page(s) : p. 30-32 Note générale : Bibliogr. Langues : Multilingue (mul) Catégories : Chimie biomimétique Colles:Adhésifs Dopa La 3,4-dihydroxyphénylalanine (abréviée en DOPA ou dopa) est une substance intermédiaire dans la synthèse des catécholamines. Elle possède deux isomères optiques, la L-DOPA ou L-dopa (ou lévodopa, dénomination pharmacologique internationale), lévogyre, et la D-DOPA ou D-dopa, dextrogyre. La L-DOPA est la forme stéréo-isomérique lévogyre métabolisable par l'organisme. Sa décarboxylation par la DOPA-décarboxylase produit la dopamine. La L-DOPA est capable de franchir la barrière hémato-encéphalique. C'est une substance qui est utilisée dans le traitement de la maladie de Parkinson en augmentant le taux de dopamine. Prothèses de hanche Index. décimale : 668.3 Adhésifs et produits semblables Résumé : The number of people receiving artificial hip joints is increasing. Unfortunately, conventional prostheses often fail to adapt to the dynamic changes of the bone. They loosen and surgery is subsequently required. This problem may be solved by a biomimetic adhesive that supports ingrowth and enables permanent adhesion. Note de contenu : - A synthetic, yet biomimetic coating - Enhanced stability and bone integration - Comparison with other prosthesis coating technologies - Future research direction - Magnetic nanoparticles for future applications - Fig. 1 : Using 3D printing, the dopamine-based tissue adhesive is applied to a three-dimensional titanium stem of a hip joint - Fig. 2 : Mussel glue is based on dopamine-containing proteins ; the "DOPA" ensures excellent adhesive properties on surfaces En ligne : https://drive.google.com/file/d/1WFDuBPZ4Z0uxwoo3XR8exakrToVw4cSj/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=41397 [article]

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Static, fatigue and stress-shielding analysis of the use of different PEEK based materials as hip stem implants / Mustafa Guven Gok in INTERNATIONAL POLYMER PROCESSING, Vol. 37, N° 2 (2022)  

[article]  inINTERNATIONAL POLYMER PROCESSING > Vol. 37, N° 2 (2022) . - p. 152-163 Titre : Static, fatigue and stress-shielding analysis of the use of different PEEK based materials as hip stem implants Type de document : texte imprimé Auteurs : Mustafa Guven Gok, Auteur Année de publication : 2022 Article en page(s) : p. 152-163 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Eléments finis, Méthode des Matériaux -- Fatigue Matières plastiques -- Propriétés mécaniques Polyéther éther cétone Polymères en médecine Prothèses de hanche Statique Index. décimale : 668.4 Plastiques, vinyles Résumé : There is a possibility that hip joints may become dysfunctional due to age, wear or some accidents, and in this case they need to be replaced with hip implants. However, after conventional hip stem implantation, the load transferred to the bone usually decreases due to the high stiffness of the metallic (most commonly Ti6Al4V, CoCr or stainless steel) hip stem implant, and as a result, mineral loss occurs in the bone which weakens. On the other hand, PEEK is an advantageous material with its low cost, ease of production, corrosion resistance and biocompatibility. More importantly, it has the potential to be a good alternative to metallic materials in load-bearing bone replacements, thanks to its mechanical properties and density close to that of the bone. In this study, hip stem implants having three different commercial PEEK materials and four different metallic main spar designs were modeled. Their behavior under static and dynamic loading conditions was analyzed according to ASTM-F2996-20 and ISO-7206-4:2010 standard test methods, and the stress-shielding effect of hip stems modeled as implanted into the femur was simulated using ANSYS commercial finite element analysis software. According to the results, it was observed that CFP based hip stem models meet the five million life time criteria and increase the stress on the femur bone by up to 57%. Note de contenu : - MATERIALS AND METHODS : Hip stem implant design - Meshing and boundary conditions - Material properties - RESULTS AND DISCUSSION : Analysis of hip stems under static load - Fatigue analysis - Stress-shielding analysis - Table 1 : Mesh parameters of finite element modelling - Table 2 : Mechanical properties of the materials - Table 3 : Maximum equivalent (Von Mises) stresses on body and main spar of hip stem, and total weights of the hip stems - Table 4 : Minimum number of cycles, minimum safety factor and maximum equivalent alternating stress values DOI : https://doi.org/10.1515/ipp-2021-4133 En ligne : https://drive.google.com/file/d/1qjmiTwYMmyJlIf2FysRVP1dmA0nw6nT2/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37621 [article]

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