| Titre : |
Inflammaging : the new theory in skin ageing |
| Type de document : |
texte imprimé |
| Auteurs : |
Philippe Moussou, Auteur ; Louis Danoux, Auteur ; Florence Henry, Auteur |
| Année de publication : |
2012 |
| Article en page(s) : |
p. 47-50 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge
Biomolécules actives
Cosmétiques
Extraits de plantes:Extraits (pharmacie)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Several research studies on aged people carried out by different research teams have highlighted the existence of a new theory in skin ageing named 'inflamming'. Skininflammaging results from a combination of several deleterious pathways inducing a vicious cycle of micro-inflammation. A cascade of inflammatory responses results in chronic low level inflammation and leads to accumulation of molecular and cellular damages, well-known sources of skinageing which can affect the appearance of the skin. Laboratoires Sérobiologiques (LS) -now with Beauty Creations - developed the first cosmetic active - a bark extract from Eperua falcata - which targets inflamming in a comprehensive way, by addressing the consequences of its deleterious effects on the skin in a particularly efficient manner. |
| Note de contenu : |
- MATERIALS AND METHODS : TNFα-induced NF-κB nucelar translocation on human keratinocytes (in vitro test) - TNFα-induced IL-8 release on human keratinocytes (in vitro test) - CGRP release from cultured sensory neurons (in vitro test) - Plasmin inhibition (in vitro test) - Improvement of skin biomechanical properties and barrier function (in vivo test)
- RESULTS AND DISCUSSION : Inhibition of NF-κB pathway and IL-8 release (in vitro test on human keratinocytes) - Inhibition of release of pro-inflammatory neuropeptide CGRP by sensory neurons (in vitro test) - Inhibition of plasmin (in vitro test) - Protection against environmental and oxidative stresses (in vitro test, data not shown) - Improvement of skin biomechanical properties and barrier function (in vivo test) |
| En ligne : |
https://drive.google.com/file/d/1gbQ2Ke_9fRLj6HeiYe98Zwr5bGih6jOE/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=15195 |
in PERSONAL CARE EUROPE > Vol. 5, N° 3 (06/2012) . - p. 47-50
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Inflammaging : the new theory in skin ageing in PERSONAL CARE EUROPE, Vol. 5, N° 3 (06/2012)
